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NCT ID: NCT00927810 Completed - Gouty Arthritis Clinical Trials

Long Term Study of Canakinumab (ACZ885) in Patients With Gout

Start date: June 5, 2009
Phase: Phase 2
Study type: Interventional

This 24-week open-label extension study is designed to provide additional long-term safety data up to a total of 1-year for patients rolling over from the core study, and to collect further efficacy and tolerability data for all the patients, irrespective whether they have an acute flare of gout or not. Patients will be treated on demand with canakinumab (ACZ885) in this extension study.

NCT ID: NCT00927667 Completed - Hemophilia A Clinical Trials

Joint Status in Subjects With Severe Hemophilia A in Relation to Different Treatment Regimens

Start date: June 2009
Phase: Phase 4
Study type: Interventional

The joint status (knees, ankles) of patients suffering from severe Hemophilia A (too little blood clotting factor VIII in blood) is evaluated in a single magnetic resonance imaging session. No study medication is given.

NCT ID: NCT00927420 Completed - Bipolar Disorder Clinical Trials

Epidemiological Study to Evaluate Adherence to Treatment in Bipolar Disorder: Adherence Study

Start date: July 2009
Phase: N/A
Study type: Observational

The purpose of this study is to estimate adherence to treatment in bipolar patients, to characterize patients based on adherence degree and to describe the variables linked to poor adherence to treatment in real-life practice.

NCT ID: NCT00927043 Completed - Clinical trials for Carcinoma, Renal Cell

Study Evaluating Renal Cell Carcinoma Risk Factors

MICRA
Start date: May 2009
Phase: N/A
Study type: Observational

This is an epidemiological, prospective, multicenter study designed to identify the pre-treatment clinical, molecular and genetic prognostic factors associated with progression free survival in patients naïve to renal cell carcinoma (RCC) treatment.

NCT ID: NCT00926328 Completed - Gingivitis Clinical Trials

Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis

Start date: June 2007
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.

NCT ID: NCT00925860 Completed - Clinical trials for Acute Respiratory Failure

Non-Positive Pressure Ventilation in Hypoxemic Patients

Start date: June 2001
Phase: Phase 4
Study type: Interventional

The study is aimed to assess the possible benefit of non-positive pressure mechanical support in front of conventional ventilation in patients admitted to the intensive care unit (ICU) because of pure hypoxemic respiratory failure.

NCT ID: NCT00925587 Completed - Anemia Clinical Trials

Evaluation of Monthly Darbepoetin Alfa Dosing for Correction of Anemia in Non-dialysis Chronic Kidney Disease

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether once monthly (QM) dosing of darbepoetin alfa is non-inferior to that of once every 2 week (Q2W) dosing of darbepoetin alfa for the correction of anemia in patients with Chronic Kidney Disease who are not receiving dialysis.

NCT ID: NCT00925301 Completed - Fabry Disease Clinical Trials

Study of the Effects of Oral AT1001 (Migalastat Hydrochloride) in Patients With Fabry Disease

Start date: October 23, 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to compare the effect of migalastat (123 milligrams [mg] of migalastat [equivalent to 150 mg of migalastat hydrochloride]) (migalastat) versus placebo on kidney globotriaosylceramide (GL-3).

NCT ID: NCT00924937 Completed - Diabetes Mellitus Clinical Trials

CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention

CORDIOPREV
Start date: November 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effects of the consumption of two different dietary patterns (low fat versus Mediterranean Diet) on the incidence of cardiovascular events of persons with coronary disease.

NCT ID: NCT00924638 Completed - Clinical trials for Cryptogenic Ischemic Stroke

Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke

CRYSTAL-AF
Start date: June 2009
Phase: Phase 4
Study type: Interventional

The 2006 American Heart Association / American Stroke Association Council on Stroke Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic recommended that patients with cryptogenic stroke take antithrombotic drugs (i.e. aspirin) in order to prevent a second stroke. When a stroke patient is found to have atrial fibrillation (AF), the guidelines recommend oral anticoagulation due to its superior efficacy over aspirin for stroke prevention. Physicians can best optimize the use of medicines only if they can precisely and correctly diagnose a patient's AF. The purpose of this study is to evaluate the time to first AF by 6 months' continuous rhythm monitoring versus control treatment in subjects with a recent cryptogenic stroke or Transient Ischemic Attack (TIA) without history of AF.