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NCT ID: NCT01176682 Completed - Clinical trials for Rheumatoid Arthritis

Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder

EVIDENCE
Start date: August 2010
Phase: N/A
Study type: Observational

The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients comply with their treatment and how satisfied they are with their treatment.

NCT ID: NCT01176266 Completed - Hypophosphatasia Clinical Trials

Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)

Start date: July 2010
Phase: Phase 2/Phase 3
Study type: Interventional

This clinical trial was conducted to study hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone. The purpose of this study was to test the safety and efficacy of a study drug called asfotase alfa (human recombinant tissue non-specific alkaline phosphate fusion protein) to see what effects it has on patients 5 years of age or less with HPP.

NCT ID: NCT01176032 Completed - Hypertension Clinical Trials

ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling

ALLMARK
Start date: June 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess efficacy of aliskiren for reducing circulating levels of biomarkers of left ventricular (LV) remodeling associated with LV hypertrophy (LVH) in hypertensive patients.

NCT ID: NCT01175824 Completed - Clinical trials for Diabetes Mellitus, Type 2

Comparison of the Efficacy and Safety of Two Insulin Intensification Strategies

Start date: April 2011
Phase: Phase 4
Study type: Interventional

The study is a comparison of twice-daily insulin lispro low mixture versus once-daily basal insulin glargine and once-daily prandial insulin lispro, in participants with Type 2 Diabetes.

NCT ID: NCT01175421 Completed - Sleep Apnea Clinical Trials

Multidimensional System as Predictor of Outcomes in Obstructive Sleep Apnea: The OSA-SCORE

OSA-SCORE
Start date: May 2010
Phase: N/A
Study type: Observational

Purpose: In a retrospective cohort the investigators will validate, the goodness of a multidimensional index to classified the severity of patients with sleep disordered breathing that has been previously developed in a prospective longitudinal cohort.

NCT ID: NCT01175304 Completed - Sleep Clinical Trials

Study of Sleep Habits and Prevalence of Sleepiness in a Health Care Environment in Barcelona

Start date: August 2010
Phase: N/A
Study type: Observational

The purpose of this study is the description of sleeping habits in a working population in the investigators health care environment, analyzing the prevalence of daytime sleepiness and symptoms compatible with the sleep apnea syndrome and finally to analyze predictors of daytime sleepiness.

NCT ID: NCT01174446 Completed - Hemophilia B Clinical Trials

Pivotal Study (Pharmacokinetics, Efficacy, Safety) of BAX 326 (rFIX) in Hemophilia B Patients

Start date: July 29, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this pivotal Phase 1/3 study is to determine the pharmacokinetic (PK) parameters, the hemostatic efficacy, and the safety of BAX 326, a recombinant factor IX, in previously treated patients (PTPs) with severe and moderately severe hemophilia B.

NCT ID: NCT01173614 Completed - Clinical trials for Normal Subjects, Ametropia

Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes

Gullstrand
Start date: January 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine the average values of human ocular biometry and to correlate these values with visual function.

NCT ID: NCT01172938 Completed - Psoriatic Arthritis Clinical Trials

Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis

PALACE-1
Start date: June 2, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis, specifically in improving signs and symptoms of psoriatic arthritis (tender and swollen joints, pain, physical function) in treated patients.

NCT ID: NCT01172483 Completed - Chronic Disorders Clinical Trials

Effectiveness of Community-Based Physiotherapy Versus General Practice

ECACOM
Start date: December 2009
Phase: N/A
Study type: Interventional

Summary: (Objectives and methodology of the project) AIM: To evaluate the clinical effectiveness of Community physiotherapy intervention on chronic diseases (heart disease, chronic obstructive pulmonary disease, back pain, mechanical neck pain, fibromyalgia, osteoarthritis lower limbs, neurological and cancer survivors) and a group of healthy patients cardiovascular risk factors. DESIGN: Randomized, controlled, prospective study. SUBJECTS OF STUDY: Patients with chronic disease go to the Local Sports Torremolinos Center INTERVENTION: Establishment of a control group that give you some advice education care (brief advice) and a group common experimental multimodal program of 12 weeks therapeutic exercise with health education (brief advice). It will follow up complete with ratings pre and post intervention to both groups and follow up at 6 and 12 months for long-term effect through specific questionnaires for each subgroup chronic disease and pain score (visual scale analog), quality of life (EuroQol-5D) and state health general (Short-Form 12, SF-12) VARIABLES: The intervention physical therapy Community. Result: Specific questionnaires for each subgroup, pain (Visual analogue scale), quality of life (EuroQoL) and general health status (SF-12). DATA ANALYSIS: descriptive statistics, measuring central tendency and dispersion of the variables study. Inferential statistics will be made between intervention of key variables and outcome (Chi square, Student t, ANOVA, Mann-Whitney, Wilcoxon, by type and normal variables). Likewise, establish measures of effect size in main outcome variables, by reduction relative risk, absolute risk and odds ratio with their respective confidence intervals.