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NCT ID: NCT01303029 Completed - Clinical trials for Metastatic Pancreatic Cancer

Safety and Efficacy Study of Gemcitabine-erlotinib Versus Gemcitabine-erlotinib-capecitabine in Patients With Metastatic Pancreatic Cancer

GECA
Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy of the combination of gemcitabine-erlotinib versus gemcitabine-erlotinib-capecitabine in patients with metastatic pancreatic cancer.

NCT ID: NCT01302860 Completed - Clinical trials for Familial Cold Autoinflammatory Syndrome

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Start date: November 2010
Phase: Phase 3
Study type: Interventional

This trial will assess the safety, efficacy and tolerability of ACZ885 in patients aged 4 years and younger with cryopyrin associated periodic syndromes (CAPS)

NCT ID: NCT01302392 Completed - Multiple Myeloma Clinical Trials

A Study of Carfilzomib vs Best Supportive Care in Subjects With Relapsed and Refractory Multiple Myeloma

FOCUS
Start date: September 2010
Phase: Phase 3
Study type: Interventional

This is a Phase 3, randomized, open-label, multicenter study comparing two treatment regimens for subjects with multiple myeloma who have received all available approved treatment options and may therefore be considered candidates for palliative care.

NCT ID: NCT01301716 Completed - Solid Cancers Clinical Trials

A Study of the Safety and Pharmacology of GDC-0980 in Combination With Either Paclitaxel and Carboplatin (With or Without Bevacizumab) or Pemetrexed and Cisplatin in Patients With Solid Tumors

Start date: September 2011
Phase: Phase 1
Study type: Interventional

This is an open-label, multicenter, Phase Ib dose-escalation study to assess the safety, tolerability, and pharmacokinetics of GDC-0980 administered with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin to patients with locally advanced or metastatic solid tumors.

NCT ID: NCT01300819 Completed - Clinical trials for Idiopathic Parkinson's Disease

Placebo-controlled Study in Patients With Parkinson's Disease to Evaluate the Effect of Rotigotine on Non-motor Symptoms

Start date: February 2011
Phase: Phase 4
Study type: Interventional

The primary objective of this study was to demonstrate that Rotigotine improves non-motor symptoms compared to Placebo in subjects with Parkinson's Disease.

NCT ID: NCT01299480 Completed - Clinical trials for Meningococcal Vaccine

A Trial To Assess The Safety, Tolerability, And Immunogenicity Of Rlp2086 Vaccine When Administered In Either 2- Or 3-Dose Regimens In Healthy Subjects Aged ≥11 To <19 Years

Start date: March 3, 2011
Phase: Phase 2
Study type: Interventional

This study is to look at a new vaccine that might prevent meningococcal disease, and to look at the safety of the new vaccine as well as how well it is tolerated. This study will also look at this vaccine being given 2 or 3 times. This study will be done in healthy adolescents.

NCT ID: NCT01299350 Completed - Heart Failure Clinical Trials

Nt-proBNP Versus Clinical Guided Discharge in Acute Heart Failure

Start date: November 2010
Phase: Phase 4
Study type: Interventional

Our objective is to compare a policy of hospital discharge guided by NT-proBNP levels versus discharge guided by conventional clinical criteria, in patients admitted with acute heart failure. The hypothesis is that the Nt-proBNP guided discharge will shorten hospital stay without worsening the outcome

NCT ID: NCT01299272 Completed - Clinical trials for Major Depressive Disorder

A Study in Prevention of Re-emergence of Depression Symptoms

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to assess the maintenance of efficacy of LY2216684 compared with placebo as adjunctive therapy to selective serotonin reuptake inhibitors (SSRIs) as measured by the time-to-symptom reemergence among participants with major depressive disorder (MDD) who met randomization criteria with adjunctive LY2216684 during the stabilization period. This trial consists of two distinct periods: an open-label treatment period, which consists of two parts, 8 weeks acute open-label with movement to 12 weeks open-label stabilization if participants are in remission at end of 8 weeks (open-label for 20 weeks total) followed by a randomized, double-blind, placebo-controlled period for 24 weeks.

NCT ID: NCT01299155 Completed - Cataract Clinical Trials

A Comparison of Visual Function After Bilateral Implantation of Presbyopia Correcting Intraocular Lenses

Start date: March 2011
Phase: N/A
Study type: Interventional

To prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with AcrySof ReSTOR +3 vs. those bilaterally implanted with LENTIS MPlus Intraocular Lens (IOL).

NCT ID: NCT01298700 Completed - Glaucoma Clinical Trials

Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Start date: May 31, 2011
Phase: Phase 4
Study type: Interventional

This study will evaluate the long-term safety of bimatoprost 0.01% ophthalmic solution compared with bimatoprost 0.03% ophthalmic solution in patients with glaucoma or ocular hypertension.