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NCT ID: NCT02183870 Completed - Lung Cancer Clinical Trials

EUCROSS: European Trial on Crizotinib in ROS1 Translocated Lung Cancer

EUCROSS
Start date: May 2014
Phase: Phase 2
Study type: Interventional

EUCROSS is a phase II trial to evaluate the efficacy and safety of crizotinib in patients with adenocarcinoma of the lung harbouring ROS1 translocations. Patients will be treated with 250mg crizotinib bid until progression or intolerable toxicity.

NCT ID: NCT02182440 Completed - Acute Kidney Injury Clinical Trials

A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI

STOP-AKI
Start date: December 18, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether recombinant Alkaline Phosphatase (recAP) is effective and save, and to determine the most effective dose, in the treatment of patients with acute kidney injury caused by sepsis.

NCT ID: NCT02181738 Completed - Hodgkin Disease Clinical Trials

Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational)

CheckMate 205
Start date: August 12, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Nivolumab in previously treated (cohorts, A, B & C) or newly diagnosed (cohort D) classical Hodgkin Lymphoma participants.

NCT ID: NCT02181686 Completed - Heart Failure Clinical Trials

Iperia/Sentus QP Study

Start date: July 2014
Phase: N/A
Study type: Observational

The objective of this study is to confirm the safety and efficacy of the new Sentus OTW QP LV lead and Iperia ICD family. The study focuses on the safety and efficacy of the QP device system.

NCT ID: NCT02181673 Completed - Clinical trials for Arthritis, Psoriatic

A Study of Golimumab in Participants With Active Psoriatic Arthritis

Start date: September 8, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of intravenously (administration of a fluid into the vein) administered golimumab 2 milligram per kilogram (mg/kg) in participants with active psoriatic arthritis (a chronic inflammatory arthritis that is associated with psoriasis).

NCT ID: NCT02180386 Completed - Clinical trials for Global Behaviour Measure

Effect of PlayStation Distraction in the Dental Setting

Start date: June 2014
Phase: N/A
Study type: Interventional

The aim of the study was to assess whether the behavior, anxiety, and dental pain of pediatric patients during dental treatment improves when a video game is played as method of distraction.

NCT ID: NCT02180217 Completed - Cushings Disease Clinical Trials

Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease

Start date: October 6, 2014
Phase: Phase 3
Study type: Interventional

The study aimed to confirm long-term efficacy and safety of LCI699 for the treatment of patients with Cushing's disease. It was a pivotal trial which supported the registration of LCI699 for the treatment of patients with Cushing's disease in the US and the EU. This is a phase lll, multi-center, double-blind, randomized withdrawal study of LCI699 following a 24 week, single-arm, open-label dose titration and treatment period which evaluated the safety and efficacy of LCI699 for the treatment of patients with Cushing's disease.

NCT ID: NCT02178956 Completed - Gastric Cancer Clinical Trials

A Study of BBI608 Plus Weekly Paclitaxel to Treat Gastric and Gastro-Esophageal Junction Cancer

BRIGHTER
Start date: October 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out whether it is better to receive a new drug, BBI608, in addition to paclitaxel chemotherapy or better to receive paclitaxel chemotherapy alone as second line treatment for gastric and gastroesophageal junction cancer after prior first line platinum and fluoropyrimidine based chemotherapy.

NCT ID: NCT02178657 Completed - Ischemic Stroke Clinical Trials

Intra-arterial Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke

Start date: April 2015
Phase: Phase 2
Study type: Interventional

This trial aims to test that intra-arterial injection of autologous bone marrow mononuclear cells in acute ischemic stroke patients is safe and improves neurological outcomes.

NCT ID: NCT02178371 Completed - Hemiplegia Clinical Trials

Constraint Induced Movement Therapy on Infantile Hemiplegia

Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the functionality of the affected upper limb in infantile hemiplegia by applying a protocol of modified constraint-induced movement therapy.