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NCT ID: NCT02680938 Recruiting - Clinical trials for Postpartum Hemorrhage

Prophylactic Use of Intraumbilical Vein Oxytocin Injection in The Management of Third Stage of Labor

Start date: January 2015
Phase: Phase 1
Study type: Interventional

The third stage is the interval between delivery of the infant and delivery of the placenta. This stage averages 10 minutes and is considered prolonged if it lasts longer than 30 minutes, placental separation occurs as a result of continued uterine contractions, continued contractions control blood loss by compression of spiral arteries and also result in migration of the placenta into the lower uterine segment and then through the cervix. The intra-umbilical vein injection of 10 IU of oxytocin is recommended as a first line of treatment for retained placenta. Despite this recommendation, the method has yet to make its way into routine practice, probably because of the lack of a large substantive randomized controlled trial, and lingering doubts over which uterotonic to use and at what dosage. The purpose of this study is to evaluate the effect of intraumbilical vein injection of oxytocin on reducing the duration of the third stage of labor and the need for manual delivery of placenta, ,in addition to reduce blood loss during third and fourth stage of labor and decrease incidence of rtained placenta in comparison with inraumblical injection of normal saline. This is a prospective randomized control trial conducted at Ain Shams University Maternity Hospital. This study included 240 term pregnant women in labor admitted to the labor ward, They were divided into Two groups : Group (A): The experimental group, 10 units of oxytocin will be injected into the umbilical vein at the most proximal site to the placenta after clamping and cutting of the umbilical cord. Group (B): The control group, 1 mL normal saline will be injected into the umbilical vein at the most proximal site to the placenta after clamping and cutting of the umbilical cord.

NCT ID: NCT02675595 Recruiting - Pregnancy Clinical Trials

5D Versus Conventional 2D Fetal Echocardiography During Second Trimester of Pregnancy

Start date: January 2016
Phase: N/A
Study type: Observational [Patient Registry]

Hypothesis: In Women in the second trimester of pregnancy 5D offers an alternative method for fetal Echocardiography compared to conventional 2D scanning Question: Does 5D software technology is as efficient as 2D scanning in fetal echocardiography of second trimesteric fetuses? Aim: This study aims at assessing the accuracy of performance of the 5D as a new scanning technology in fetal Echocardiography compared to the conventional use of 2D scanning.

NCT ID: NCT02673359 Recruiting - Premature Labour Clinical Trials

Vaginal Progesterone Versus Cervical Cerclage for Pregnant Women With Short Cervix and History of PTL and/or MTM

Start date: February 2016
Phase: Phase 4
Study type: Interventional

The aim of this study to compare vaginal progesterone supplementation to cervical cerclage for prevention of preterm labor in women with short cervical length and history of previous midtrimester miscarriage and/or preterm labor.

NCT ID: NCT02669277 Recruiting - Clinical trials for Newly Diagnosed Pediatric ITP

Safety, Tolerability and Efficacy of Single Dose Low Cost Minipool Intravenous Immunoglobulins in Moderately Severe Newly Diagnosed ITP

Start date: August 2015
Phase: Phase 2
Study type: Interventional

To demonstrate the efficacy of new product IVIG prepared by minipool technology as assessed by Bleeding Score and platelet count at 3 days, 1 week, 2 weeks and 4 weeks. The platelet response rate is defined as the percentage of subjects responding to treatment with an increase of platelet count from ≤ 20 x 10^9/L to ≥ 100 x 10^9/L and absence of bleeding (complete response) or platelet count ≥ 50 x 10^9/L and at least 2-fold increase the base line count with absence of bleeding (partial response), within the specified time frame.

NCT ID: NCT02668354 Recruiting - Infantile Neoplasms Clinical Trials

Cancer in Infants: South Egypt Cancer Institute Experience

Start date: February 1, 2017
Phase:
Study type: Observational

The aim of this study is to investigate the spectrum of various types of malignant neoplasms of infancy, according to the experience of South Egypt Cancer Institute, which represents the largest referral site in Upper Egypt.

NCT ID: NCT02665676 Recruiting - Clinical trials for Neoplasms, Embryonal

Embryonal Tumors of Infancy & Childhood: South Egypt Cancer Institute Experience

Start date: July 1, 2019
Phase:
Study type: Observational

The aim of this study is to investigate demographic & disease characteristics of pediatric cancer patients diagnosed with one of embryonal tumors to identify the prevalence, the spectrum of these disease entities & treatment outcomes in these patients.

NCT ID: NCT02665572 Recruiting - Clinical trials for Renal Transplantation Into a Defunctionalized Bladder

Outcome of Renal Transplant on a Defunctionalized Bladder

Start date: August 2015
Phase: N/A
Study type: Interventional

In this study, investigators will prospectively evaluate the outcome of renal transplantation into a defunctionalized bladder by comparing direct transplantation into this defunctionalized bladder and pre-transplant programmed bladder cycling.

NCT ID: NCT02660658 Recruiting - Lower Limb Surgery Clinical Trials

Optimal Single Dose Intrathecal Dexmedetomidine for Postoperative Analgesia

Start date: January 2016
Phase: N/A
Study type: Interventional

Spinal anesthesia is a commonly used technique for lower limb surgeries offering better quality of postoperative analgesia, lower incidence of side effects, and shorter post-anesthesia care unit stay than general anesthesia. However, the relatively short duration of action of the currently available local anesthetics (LAs) make these advantages short-lived. The risk for local anesthetic toxicity (LAST) increases with the trials to use higher concentrations or volumes of intrathecal local anesthetics to increase the duration of analgesia. Dexmedetomidine has the potential to prolong the duration of perioperative analgesia without the need for using high doses of local anesthetics and hence with decreasing the potential risk of local anesthetic, but the increased likelihood adverse effects such as short term bradycardia and prolonged duration of motor block may offset these benefits.

NCT ID: NCT02658695 Recruiting - Infertility History Clinical Trials

Evaluation of the Relationship Between Air Bubbles Depth and Pregnancy Rate in ICSI Cycles

Start date: April 2015
Phase: N/A
Study type: Observational [Patient Registry]

The aim of this work is to assess the effect of air bubbles localization inside the uterus on embryo transfer outcome in ICSI cycles. Is there a relationship between embryo transfer outcome and the distance between fundal endometrial surface and air bubbles assessed by trans-abdominal ultrasound?

NCT ID: NCT02656108 Recruiting - Labor Stage, Third Clinical Trials

Omission of Controlled Cord Traction During Active Management of Third Stage of Labor

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This is a comparative study which will be conducted in Ain Shams University Maternity hospital to assess the individual and specfic role of controlled cord traction as a part of active management of third stage of labor