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NCT ID: NCT03655275 Recruiting - Clinical trials for Temporomandibular Joint Disorders

Effects of Platelet-rich Plasma Prolotherapy of Temporomandibular Joint Subluxation

Start date: August 24, 2018
Phase: Early Phase 1
Study type: Interventional

The aim of this study is to clinically assess the efficacy of PRP prolotherapy for treatment of TMJ subluxation

NCT ID: NCT03653065 Recruiting - Clinical trials for Mechanical Ventilation Outcomes

Assiut University Children Hospital Egypt

Start date: August 2018
Phase:
Study type: Observational

Frequency and outcomes of mechanical ventilation In intensive care unit at Assiut university children hospital.

NCT ID: NCT03648190 Recruiting - Bleeding Clinical Trials

Platelet Glycoproteins in Inherited Thrombocytopathy: Association With Aggregation Studies and Bleeding Severity

Start date: December 1, 2018
Phase:
Study type: Observational

Disorders of platelet function are characterized by variable mucocutaneous bleeding manifestations and excessive hemorrhage following surgical procedures or trauma. Generally, most patients have mild to moderate bleeding manifestations with a prolonged bleeding time. Platelet aggregation and secretion studies using platelet-rich plasma (PRP) provide evidence for platelet dysfunction but are neither predictive of severity of clinical manifestations nor the molecular mechanisms. Glanzmann's thrombasthenia (GT) is a rare autosomal recessive genetic bleeding syndrome characterized by defects in platelet aggregometry. The clinical phenotype of patients with GT is variable. Some suffer from severe bleeding, while others have only mild bleeding. Some studies found bleeding severity in GT was influenced by the abundance and functioning of platelet receptors involved in aggregation and adhesion. In addition to a complete medical history, a GT diagnosis requires a comprehensive laboratory workup, including platelet aggregation analysis, and a confirmation by flowcytometry or western blotting with monoclonal antibodies that recognize the GPIIb/IIIa complex. Platelet flow cytometry is an emerging tool in diagnostic and therapeutic hematology. It is eminently suited to study the expression of platelet surface receptors both qualitatively as well as quantitatively. Aim of the study:- - Determine the role of flowcytometry as a quantitative measurement tool of platelets surface glycoproteins in patients with inherited thrombocytopathies and its correlation with bleeding severity of these patients. - To compare the efficacy, advantages and disadvantages between platelets flowcytometry and aggregometer in diagnosing various inherited thrombocytopathies.

NCT ID: NCT03647865 Recruiting - Microgenia Clinical Trials

Evaluation of The Accuracy of CAD-CAM Custom Made Titanium Miniplates In Positioning of the Genial Segment in Computer Guided Genioplasty

Start date: September 2018
Phase: N/A
Study type: Interventional

In patients with chin deformeties, will using a custom made titanium plate in the positioning of the genial segments give an accurate results in comparison to the preoperative planned osteotomy and move of the Genioplasty.

NCT ID: NCT03647072 Recruiting - Lymphoma Clinical Trials

PPI Versus Histamine Antagnists as Adjuvant to Chemotherapy

Start date: August 1, 2018
Phase: Phase 3
Study type: Interventional

The study is a Comparative Clinical and Biochemical Study Evaluating the effect of Proton Pump I nhibitors versus histamine 2 Receptor antagonists as an adjuvant with chemotherapy in patients with Non-hodgkin Lymphoma.

NCT ID: NCT03646396 Recruiting - HCV Coinfection Clinical Trials

Effect of Sofosbuvir-daclatasuvir on Angiogenesis

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The study aimed at study of the Effect of Daclatasvir Plus Sofosbuvir on Angiogenesis in Egyptian Patients With Chronic HCV Infection

NCT ID: NCT03645187 Recruiting - Colon Cancer Stage Clinical Trials

Celecoxib as Adjuvant Therapy to Chemotherapy in Patients With Metastatic Colorectal Cancer

Start date: August 1, 2018
Phase: Phase 4
Study type: Interventional

The study aimed at evaluation of anticancer effect of celecoxib as adjuvant therapy to chemotherapy in patients with metastatic colorectal cancer

NCT ID: NCT03644537 Recruiting - Root Resorption Clinical Trials

Correlation Between Root Resorption and Dentin Sialoprotein Upon Application of Different Orthodontic Forces.

Start date: October 7, 2017
Phase: N/A
Study type: Interventional

Since root resorption is a frequent consequence of orthodontic treatment, DSP are non-collagenous dentin-specific matrix proteins postulated to be involved in the mineralization of pre-dentin into dentin. Calculating the amount of DSP -Dentine Sialo Protein- produced upon root resorption might be an indicative biological marker for root resorption

NCT ID: NCT03643471 Recruiting - Clinical trials for Temporal Lobe Epilepsy

Advanced Magnetic Resonance Imaging in Temporal Lobe Epilepsy

Start date: January 2019
Phase:
Study type: Observational

We aim to o evaluate the role of conventional and advanced MRI sequences in diagnosis of idiopathic temporal lobe epilepsy including identification and lateralization of epileptogenic focus.

NCT ID: NCT03640091 Recruiting - Clinical trials for Randomized Clinical Trial

Pre-extractive Inter-radicular Implant Bed Preparation Versus Conventional Post-extractive Inter-radicular Implant Bed Preparation in Mandibular Molars

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Pre-extractive Inter-radicular Implant Bed Preparation versus Conventional Post-extractive Inter-radicular Implant Bed Preparation in Mandibular Molars