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NCT ID: NCT03926676 Recruiting - Clinical trials for the Clinical Performance of Indirect Restoration Fabricated From Nanohybrid Cad Cam Composite Blocks and Ceramic Blocks

Comparing Nano Hybrid Composite Blocks With Ceramic Blocks in Indirect Restorations 2. Protocol Registration:

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

comparing nano hybrid composite blocks grandio blocks (VOCO) with ceramic blocks (Emax) in indirect restorations using modified USPH criteria (marginal integrity) to see if there will be a significant different between two blocks

NCT ID: NCT03926663 Recruiting - Clinical trials for Intranasal Dexmedetomidine

Intranasal Injection of Dexmedetomidine and Bupivacaine in Septoplasty Surgeries

Start date: July 20, 2019
Phase: Phase 4
Study type: Interventional

Pain is particularly common after nasal surgery, especially when bone manipulation and periosteal irritation are involved. Appropriate pain control is an important consideration in the post-surgical management of patients.

NCT ID: NCT03925714 Recruiting - DM Clinical Trials

Impact of P53 and SIRT1 in Type 2 Diabetes

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

Investigating the impact of p53 and SIRT1 in the development of type 2 DM

NCT ID: NCT03925701 Recruiting - dm Clinical Trials

Clinical Study Evaluating Vildagliptin Versus Vildagliptin/Metformin on NAFLD With DM

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

Clinical study evaluating vildagliptin versus vildagliptin/metformin on NAFLD with DM.

NCT ID: NCT03925662 Recruiting - Colorectal Cancer Clinical Trials

Mebendazole as Adjuvant Treatment for Colon Cancer

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

mebendazole treating colon cancer

NCT ID: NCT03922438 Recruiting - Clinical trials for Nasoalveolar Fistula (Defect)

Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually occur and remain in those patients post-operatively.

NCT ID: NCT03921125 Recruiting - Fluid Response Clinical Trials

Pleth Variability Index for Directed Fluid Optimization in Donors in Living Donor Liver Transplantation

Start date: October 9, 2018
Phase:
Study type: Observational

In this Study we are trying to validate the accuracy of Plethogram variability index in predicting fluid responsiveness compared to pulse pressure variation in donors of liver transplantation

NCT ID: NCT03921099 Recruiting - Acute Kidney Injury Clinical Trials

Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty

Start date: January 17, 2019
Phase: Phase 4
Study type: Interventional

A Randomized controlled trial aiming to investigate whether ascorbic acid has a role in preventing vancomycin induced nephrotoxicity or not in critically ill patients.

NCT ID: NCT03920449 Recruiting - Clinical trials for Chronic Anal Fissure

Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

We hypothesized that optimization of the dose of the Botulinum toxin injection (BT) and standardization of the technique of lateral internal sphincterotomy to posterolateral internal sphincterotomy (PIAS) could, in turn, report a conclusive result which helps to provide better care to patients with chronic anal fissure. So, we will conduct this trial as a prospective randomized, controlled, intervention, open-label trial with two parallel groups, and a primary endpoint of fissure healing during 6 months after the initial intervention, with the randomization, will be performed by an online software with a 1:1 allocation. Eligible patients will be randomized in equal proportions between BT injection and PIAS.

NCT ID: NCT03915990 Recruiting - Clinical trials for Diabetes Mellitus, Type 1

Middle Cerebral and Umbilical Arteries Doppler Indices in the Prediction of Adverse Neonatal Outcome Among Diabetic Pregnant Women

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

120 patients will be included and divided into two groups; Control group that will include 60 healthy pregnant women and Study group that will include 60 pregestational diabetic pregnant patients which furtherly will be subdivided into two groups according to HbA1C levels namely; controlled diabetics ( will include 30 diabetic pregnant women with controlled DM - HbA1C < 6.5 %) and uncontrolled diabetics (will include 30 diabetic pregnant women with uncontrolled DM - HbA1C ≥ 6.5 %). Umbilical and middle cerebral arteries Doppler indices (resistance index and pulsatility index) and Cerebroplacental Doppler ratio will be measured for every patient. The recorded neonatal outcomes will include neonatal birth weight, neonatal blood sugar, Apgar score at 1 & 5 min and neonatal intensive care unit admission.