Clinical Trials Logo

Filter by:
NCT ID: NCT04267458 Recruiting - Clinical trials for Investigate the Renal Effect of DAAs on Egyption Patients After Completion of Treatment

Prevalence of Kidney Injury in Patients With HCV Treated With Sofuspovir Containing DAA Therapy

Start date: July 1, 2019
Phase: Phase 4
Study type: Interventional

this study aims is to investigate the occurrence of AKI during antiviral therapy, defined as an increase of 0.3 mg/dL or 50% at least in serum creatinine level when compared with baseline values or more than a 25% reduction in (eGFR) when compared with baseline eGFR in Egyptian patients.In addition to evaluate the change in insulin resistance value after treating patients from HCV.

NCT ID: NCT04266652 Recruiting - Augmentation Clinical Trials

Using the Roots of a Non Restorable Wisdom Tooth as a Block for Augmentation of Localized Defects

Clinical
Start date: January 6, 2018
Phase: Phase 4
Study type: Interventional

assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.

NCT ID: NCT04266132 Recruiting - Inguinal Hernia Clinical Trials

Ultrasound Guided Retrolaminar Block for Pediatric Inguinal Hernia

Start date: May 17, 2020
Phase: N/A
Study type: Interventional

Regional analgesia for inguinal hernia repair in children has attracted increasing interest and different techniques like Caudal block, lumbar epidural block, wound infiltration, Ilio-inguinal nerve block and paravertebral block have been used with varying success. Ilio-inguinal nerve blockade has been widely used in this context but the duration of the block is also limited to the early postoperative period. Paravertebral blockade has been shown to produce long lasting postoperative analgesia when used in combination with general anaesthesia in paediatric herniorrhaphy . Ultrasound-guided retrolaminar block is one of the newer and technically simpler alternatives to the traditional PV block . The aim of this study is to test the efficacy and safety of ultrasound guided retrolaminar block(RLB) as an analgesic technique in surgery of pediatric inguinal hernia in comparison with with ilioinguinal nerve block(INB). It is hypothesized that RLB block will provide longer duration of postoperative analgesia than INB with few side effects.

NCT ID: NCT04264507 Recruiting - Acute Kidney Injury Clinical Trials

Prevalence , Risk Factors and Outcomes of AKI in ICU Patients

Start date: January 1, 2020
Phase:
Study type: Observational

Early recognition of AKI is essential to ensure prompt and appropriate management, and to avoid progression to late stages of the disease (2) AKI requiring renal replacement therapy occurs in 5-6% of ICU patients, with an extremely high in hospital mortality rate of 60%.6 It is estimated that about 2 million people die of AKI every year. Those who survive AKI have a higher risk for later development of CKD(3). Epidemiology of AKI is understudied in developing countries so further studies are needed to estimate the burden of AKI among ICU patients. Few studies about the epidemiology of AKI in Egypt were done;

NCT ID: NCT04263753 Recruiting - Clinical trials for Placenta Accreta With Bladder Invasion

Bladder Conservative Surgery in r Abnormally Invasive Placenta With Bladder Invasion

Start date: February 5, 2020
Phase: N/A
Study type: Interventional

Placental borders and mapping by ultrasonography and Doppler ultrasonography (placental mapping) preop. And verified intraoperatively . bladder peritoneal dissection till the level of internal Os Uterus is incised away from the placenta - Baby was delivered , the uterus is exteriorised and 4-5 towel clips are applied rapidly control uterine incision site bleeding . Twenty units of diluted oxytocin and 100 to 200 cc, 37°C of heated saline were infused from here, and then the cord was clamped . Then we proceed to systemically devascularize the uterus with the placenta in site After control of both superior vesical vessels Finding a fresh noninvaded plan between isthmocervical junction and posterior bladder wall aided by filling the bladder 150 cc saline Then cervical stump control sutures and severing the specimen above the clamps Now the placenta is only attached to the bladder , apply intestinal clamp or foley cath on the bladder below the level of invasion if feasible to reduce bleeding - cut through the placenta, heavy back flow bleeding of old blood stored in the placenta will be noticed , but there is no hemodynamic change since the cervical stump is already severed , dissect the bladder with a large safety margin cutting through the placenta.. Then in cases with hematuria saline irrigation of the bladder is usually enough to clear the hematuria 15 out of 20 In cases with larger blood clots in the bladder cystoscope is done avoiding the need for cystotomy - lastly removal of excessive placental tissues from the bladder wall by gentle swabbing or trimming, then individual control of bleeders and plication of the invaded area with seromuscular purse string sutures around said area , in cases of large areas , bladder mobilization is imperative to increase bladder capacity

NCT ID: NCT04262037 Recruiting - Clinical trials for Pulmonary Hypertension

A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergoing Congenital Heart Surgeries

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Aim of Work: The aim of this randomized, double-blinded, study is to compare between three modes of ventilation during cardiopulmonary bypass in pediatric patients with pulmonary hypertension undergoing corrective cardiac surgeries. Hypothesis: The hypothesis of the present study is that high frequency low volume positive pressure ventilation is better than continous positive airway pressure (CPAP)and passive deflation on direct PAP (pulmonary artery pressure ) reading and immediate oxygenation after cardiopulmonary bypass CPB in pediatric patients undergoing cardiac surgeries for congenital heart defects.

NCT ID: NCT04258696 Recruiting - Clinical trials for Endodontically-Treated Teeth

Assessment of Lateral and Vertical Tissue Displacement Obtained by the Retraction Cord and Diode Laser

Start date: June 30, 2020
Phase: N/A
Study type: Interventional

In fixed prosthodontic treatment, deflection of gingival tissues for diagnosis or making an impression is one of the important phases. Gingival displacement is defined as "displacement of gingival tissues both in vertical and lateral dimensions". Lateral retraction displaces the tissues so that an adequate bulk of impression material can be interfaced with the prepared tooth. Vertical retraction exposes the uncut portion of the tooth apical to the finish line Conventional gingival retraction cord technique may injure the healthy epithelial lining and result in postoperative gingival recession The diode laser has been used for displacing gingiva to make a definitive impression. Rather than displacing gingival tissue, it removes the epithelial lining from the sulcus. The aim of the Study is to compare between the Ultrapak retraction cord and diode laser regarding the amount of vertical and lateral retraction and patient comfort.

NCT ID: NCT04257786 Recruiting - Advanced Cancer Clinical Trials

Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer

ovarian cancer
Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Assessment of efficacy of primary cyto-reductive surgery in patients with advanced primary epithelial ovarian cancer in Comparison to patients receiving neo-adjuvant chemotherapy (NAC) followed by surgery in complete excision of the tumor reaching R0 without significant morbidity.

NCT ID: NCT04256824 Recruiting - Clinical trials for Surgical Site Infection

Triclosan-antibacterial Sutures Efficacy on the Incidence of Surgical Site Infection in Clean-contaminated Wounds

Start date: February 5, 2020
Phase: Phase 4
Study type: Interventional

Comparing the incidence of SSI in cases using coated Polyglactin 910 suture with Triclosan and cases using Polyglactin 910 suture without Triclosan in clean-contaminated wound surgery

NCT ID: NCT04256109 Recruiting - Oral Health Clinical Trials

Women's Access to Mobile Phones and Willingness to Utilize mHealth Interventions for Oral Health Promotion in Egypt

Start date: January 11, 2020
Phase:
Study type: Observational

In 2019, it was reported that there were 27.9 million smart phone users and 93.7 million phone subscribers in Egypt. This means that mHealth (which is the use of mobile phones in delivering health-care and public health services) could be a major asset to delivering oral health education to the secluded rural areas or the more under privileged remote areas in the future. However, in order to employ mHealth effectively, it's essential to estimate the percentage of users who, not only have access to mobile technology, but are also willing to utilize mHealth interventions. It is also of great importance to understand the patients' preferences regarding its use. This is in order to tailor an intervention that satisfies their needs for oral health related services. Therefore the aim of this study is to determine the access of Egyptian women to mobile phones, as well as their willingness to utilize mHealth interventions for oral health promotion.