Clinical Trials Logo

Filter by:
NCT ID: NCT04971434 Recruiting - Fatty Liver Clinical Trials

Fatty Liver Response of Cardio-metabolic Risk Factors to Laser Acupuncture Versus Cupping

Start date: July 11, 2021
Phase: N/A
Study type: Interventional

Every-two-week applied cupping (with scarification) session within one month on back of upper thorax is not compared previously regarding its effect on cardio-metabolic risk factors to the daily application of laser on acupoints (for month, except Fridays) in fatty liver patients. This trial will compare the two procedure effects on cardio-metabolic risk factors in fatty liver.

NCT ID: NCT04970095 Recruiting - Clinical trials for Cleft Lip and Palate

Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

Evaluate the treatment outcome of Alternate Rapid Maxillary Expansion and Constriction Alt-RAMEC protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and recorded by cone beam computed tomography (CBCT).

NCT ID: NCT04970017 Recruiting - Clinical trials for Ischemic Heart Disease

Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease

Start date: January 1, 2021
Phase:
Study type: Observational

To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.

NCT ID: NCT04966572 Recruiting - Clinical trials for Cleft Lip and Palate

Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Grayson Acrylic Formed Nasoalveolar Molding Appliances.

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either presurgical vacuum-formed nasoalveolar molding aligners VF (NAM) or conventional Grayson acrylic formed nasoalveolar molding appliances in order to evaluate their effect on the maxillary arch.

NCT ID: NCT04964349 Recruiting - Alopecia Areata Clinical Trials

Efficacy of Jessener Solution Versus Intralesional Steroid in Treatment of Alopecia Areata

AA
Start date: April 21, 2021
Phase: Early Phase 1
Study type: Interventional

Alopecia areata is believed to be an autoimmune disease. Treatment primarily relies on intralesional and topical corticosteroids. This study was conducted to evaluate Jessener Solutionas a potential therapeutic modality of Alopecia Areataversusintralesional steroid as regards the efficacy, safety, tolerability, and patients' satisfaction.

NCT ID: NCT04962789 Recruiting - Infertility, Female Clinical Trials

Endometrial Compaction in Assissted Reproduction

Start date: August 20, 2021
Phase:
Study type: Observational

To record the dynamic change of endometrial thickness (Day of embryo transfer Versus. Day of ovulation trigger administration in case of fresh cycles or end of estrogen phase in frozen cycles), and to investigate the impact of endometrial thickness change on pregnancy outcomes

NCT ID: NCT04962776 Recruiting - Clinical trials for Length of Hospital Stay

Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries

Start date: August 1, 2021
Phase: Phase 4
Study type: Interventional

Surgery is known to be associated with stress response affecting in a negative way the clinical outcome and patient experience. The stress response includes both sympathetic nervous system activation and systemic inflammatory response. The pituitary- sympathetic one leads to a number of metabolic changes as hyperglycemia, nitrogen loss and lipolysis on the other hand the systemic inflammatory response aggravates the perioperative metabolic changes. One of components of ERAS is preoperative carbohydrate load. Oral carbohydrate was associated with attenuation of the postoperative metabolic stress response. Nitrate rich drinks before exercises have a promising impact due to improving blood flow, mitochondrial efficiency, glucose uptake and the sarcoplasmic calcium handling all of which maximize resistance to fatigue and improved exercise performance.

NCT ID: NCT04961996 Recruiting - Early Breast Cancer Clinical Trials

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

Start date: August 27, 2021
Phase: Phase 3
Study type: Interventional

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with endocrine therapy of physician's choice in participants with medium- and high-risk Stage I-III histologically confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative early breast cancer. In addition, an open-label exploratory substudy will explore the safety and efficacy of giredestrant in combination with abemaciclib in a subset of the primary study population.

NCT ID: NCT04961034 Recruiting - Biliary Atresia Clinical Trials

Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop

Start date: January 2015
Phase: N/A
Study type: Interventional

the study of the effect o the hanging of the jejunal loop to the peri KPE Glisson capsule on the rate of bile drainage and requirement of liver transplantation

NCT ID: NCT04959786 Recruiting - COVID-19 Pneumonia Clinical Trials

MANS-NRIZ Trial for COVID-19 Treatment : Extension Study

Start date: April 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This search will focus on patients with COVID 19 infection this study is a prospective cohort study based on the analysis of response in comparative panel between two arm Nitazoxanide, Ribavirin and Ivermectin plus Zinc arm and other arm without any intervention as regards the safety and efficacy and cost effective result. Two years duration of the project would be enough to cover the stages of the work as shown below in the time plan. Initial stage of collecting materials and patients' clinical data, each patient will undergoes strict follow up period to reveal the clinical, laboratory and radiological response. The procedures are to be approved by the institutional ethical committee.