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NCT ID: NCT06419556 Recruiting - Anesthesia Clinical Trials

Analgesic Efficacy of an Intermediate CPB in Neck Surgeries.

Start date: March 5, 2023
Phase: N/A
Study type: Interventional

This study aims to investigate the analgesic efficacy of Intermediate Cervical Plexus Block combined with GA using two bupivacaine concentrations in patients undergoing neck surgeries (total thyroidectomy or total laryngectomy)

NCT ID: NCT06418347 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females

Start date: April 1, 2024
Phase: Phase 3
Study type: Interventional

This research study aims to investigate the effect of adding Alpha lipoic acid (ALA) supplement to letrozole treatment in infertile women with polycystic ovary syndrome (PCOS). The study will include 150 PCOS participants seeking fertility treatment. They will be randomly divided into two groups - control and intervention. Both groups will receive standard PCOS care including lifestyle counseling. The control group will be treated with letrozole only. The dose will start at (2.5 mg) for 5 days and can increase up to (7.5 mg) based on response. The intervention group will take ALA supplements along with letrozole treatment. ALA tablets (600mg) will be given three times daily starting from day 3 of the menstrual cycle till human chorionic gonadotropin (HCG) injection day. Letrozole dose for the intervention group will also follow the same incremental protocol as the control group. Patient monitoring will involve trans-vaginal ultrasound scans on certain cycle days to check follicle growth and the thickness of uterus lining. Once a follicle reaches 18mm in size, an intramuscular HCG injection will be given. Couples will be asked to have intercourse 36 hours after the injection. Pregnancy will be tested two weeks later if menstruation does not occur. Metabolic, hormonal, and ultrasound parameters will be recorded at baseline and follow-ups. All adverse effects of the treatment will be noted. The study period will be a maximum of 3 treatment cycles or untill pregnancy is achieved. Outcome measures include ovulation and pregnancy rates. The effect of ALA on metabolic parameters (fasting glucose, fasting insulin, BMI and HOMA-IR), hormone levels (mid-luteal progesterone and serum estradiol), and follicular growth will also be assessed. Proper sample size and randomization methods will be followed. A Statistical analysis of collected data will help determine if ALA has additional benefits when combined with letrozole for PCOS fertility treatment. Finally, the results will be statistically analyzed. Statistical analysis will be done using the SPSS statistical software package.

NCT ID: NCT06417593 Recruiting - Clinical trials for Pseudomonas Aeruginosa Infection

Phenotypic and Genotypic Characteristics of Pseudomonas Aeruginosa Isolates in Sohag University Hospitals

Start date: April 1, 2024
Phase:
Study type: Observational

Isolation and identification of Pseudomonas aeruginosa using basic microbiological methods, such as Gram staining, cultivation on cetrimide agar and biochemical reactions from Samples from patients with different types of health care associated infections as urinary tract infections, infected burn, ventilator associated pneumonia, blood stream infections and surgical site infections that will be obtained under complete aseptic precautions.

NCT ID: NCT06417463 Recruiting - Thyroid Nodule Clinical Trials

Role of TIRADS and Bethesda Scoring Systems in Management of Thyroid Nodules

Start date: May 12, 2024
Phase:
Study type: Observational

role of TIRADS and Bethesda scoring system in management of thyroid nodules as these methods are ultrasound clasification that helps increase the diagnostic effectiveness of thyroid nodules and reduces the use of preopeative FNA .that nodules are usually divided into diffent categories based on TIRADS and are then referred to FNA and follow up according to variable risk of maligneny.

NCT ID: NCT06417320 Recruiting - Clinical trials for Nephrotic Syndrome in Children

Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years

Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of ACE inhibitors and SGLT-2 inhibitors on: 1. Proteinuria 2. Renal survival indices

NCT ID: NCT06417268 Recruiting - Clinical trials for Pericapsular Nerve Group Block

Combined Pericapsular Nerve Group Block and Lateral Femoral Cutaneous Nerve Block for Pediatric Hip Surgeries

Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

combined pericapsular nerve group PENG block and lateral femoral cutaneous nerve block may be effective in reducing post-operative pain after open hip surgery in children.

NCT ID: NCT06416917 Recruiting - Clinical trials for Internal Rotation Contracture-shoulder

Glenohumeral Internal Rotation Deficit Among Professional Athletes

Start date: June 1, 2024
Phase:
Study type: Observational [Patient Registry]

The study aimed to identify the prevalence of GIRD among elite Egyptian volleyball players in selected clubs in Egypt.

NCT ID: NCT06416904 Recruiting - Clinical trials for Orthodontic Appliance Complication

Evaluation Of Anchorage Control During Canine Retraction Using Arch Wire Stopper Versus Mini-Screws

Start date: February 13, 2024
Phase: N/A
Study type: Interventional

The study aims to compare the anchorage control during canine retraction using arch wire stopper versus mini-screws in post-pubertal patients with maxillary dentoalveolar protrusion

NCT ID: NCT06416033 Recruiting - Leprosy Clinical Trials

Serum Irisin Level In Leprosy Patients

Start date: January 1, 2024
Phase:
Study type: Observational

- Measurement of plasma irisin level in leprosy patients. - Correlation of plasma irisin level between leprosy patients and healthy controls. - Correlation of plasma irisin level in different leprosy types.

NCT ID: NCT06414525 Recruiting - Clinical trials for Constipation Chronic Idiopathic

Effect of Abdominal Massage Versus Visceral Manipulation on Constipation

Start date: May 7, 2024
Phase: N/A
Study type: Interventional

The study compares the effect of abdominal massage vs. visceral manipulation on constipation status and quality of life in adults. Chronic idiopathic constipation (CIC) is considered a common functional bowel disorder characterized by difficult, infrequent, and/or incomplete defecation. It has a great impact on the quality of life and on the healthcare system and represents an important financial strain .