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NCT ID: NCT01249261 Completed - Clinical trials for Postmenopausal Women With Osteoporosis

Effect of Stopping Risedronate After Long Term Treatment on Bone Turnover

Start date: October 2001
Phase: Phase 3
Study type: Interventional

The effects of stopping long-term (7 years) and short term (2 years) risedronate therapy on BMD (bone mineral density) and BTMs (bone turnover markers) will be summarized.

NCT ID: NCT01248195 Completed - Schizophrenia Clinical Trials

Optimization of Treatment and Management of Schizophrenia in Europe

OPTIMISE
Start date: May 2011
Phase: Phase 4
Study type: Interventional

The purpose of the study is optimising current treatments in schizophrenia and explore novel therapeutic options for schizophrenia. The study intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new interventions. It is expected that the project will lead to evidence that is directly applicable to treatment guidelines, and will identify potential mechanisms for new drug development.

NCT ID: NCT01248039 Completed - Arthroplasty Clinical Trials

Preoperative Pain, Function, and Activity for Total Hip and Knee Arthroplasty Patients

Start date: January 2011
Phase: N/A
Study type: Observational

This study wish to show if the preoperative level of pain, function or activity for hip and knee arthroplasty patients has any predictive value of the time it takes to fulfill the well-defined discharge criteria.

NCT ID: NCT01247675 Completed - Clinical trials for Growth Hormone Deficient Adults

A Safety, Pharmacokinetic and Pharmacodynamic Study of ACP-001 (TransCon PEG hGH) in Adults With Growth Hormone Deficiency

Start date: November 2010
Phase: Phase 2
Study type: Interventional

This study investigates the pharmacokinetic profile (PK) and pharmacodynamic response (PD) of three different doses of ACP-001 given once-a-week compared to one dose-level of an approved daily human growth hormone product over a period of 4 weeks (4 weekly administrations versus 28 daily administrations).

NCT ID: NCT01247337 Completed - Cholangiocarcinoma Clinical Trials

Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Cholangiocarcinoma

Start date: February 2, 2011
Phase: Phase 2
Study type: Interventional

A phase II trial evaluating intra-hepatic chemotherapy with oxaliplatin every second week in combination with systemic gemcitabine and capecitabine in combination with cetuximab in patient with non-resectable liver metastases from cholangiocarcinoma.

NCT ID: NCT01247194 Completed - Clinical trials for Chronic Genotype 1 Hepatitis C Virus Infection

A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1

Start date: October 2010
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the safety, tolerability, antiviral effects, and pharmacokinetics of PPI-461 in patients with chronic hepatitis C virus genotype 1 infection.

NCT ID: NCT01246674 Completed - Clinical trials for Osteoarthrosis Patients With Total Hip Arthroplasty

Thigh Swelling, Hip-muscle Strength, and Functional Performance Following Total Hip Arthroplasty

THA
Start date: January 2011
Phase: N/A
Study type: Observational

By this study the investigators wish to (1) quantify hip strength and functional-performance deficits at discharge after fast-track total hip arthroplasty (THA), and (2) investigate if changes in thigh circumferences, or hip pain are correlated to changes in hip strength and functional-performance after fast-track THA.

NCT ID: NCT01246167 Completed - Clinical trials for Humeral Fractures, Proximal

Treatment of Proximal Humeral Fractures

TPHF
Start date: January 2011
Phase: N/A
Study type: Interventional

This trial is designed to compare head-to-head conservative with operative treatment in 2 stratum. Stratum 1: In 2 part fractures the comparison is between conservative treatment and operative treatment with plate fixation with Philos. Stratum 2: In multi-fragmented fractures (MFF) meaning 3 and 4 part fractures, the comparison is between conservative treatment, operative treatment with Philos plate and operative treatment with Epoca prosthesis. Subgroup analysis will be performed in an effort to obtain limit values for specific treatment of different age and fracture groups. A cost-effectiveness analysis and comparison between different treatment modalities will be carried out. The primary outcome measure will be the DASH score and the secondary outcome measure the EQ-5D value. Recruitment period is 3 years and follow-up 2 years.

NCT ID: NCT01245894 Completed - Clinical trials for Myocardial Infarction [C14.907.585.500]

Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment

Start date: November 2007
Phase: Phase 4
Study type: Interventional

The aim of this study was to measure the effect of low- and high-dose lipid-lowering treatment with rosuvastatin on the coronary physiology parameters.

NCT ID: NCT01245868 Completed - Spinal Anesthesia Clinical Trials

Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine

Start date: November 2009
Phase: Phase 4
Study type: Interventional

The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.