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NCT ID: NCT00331604 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Safety and Efficacy of Inhaled Insulin in Type 2 Diabetes

Start date: August 31, 2006
Phase: Phase 3
Study type: Interventional

This trial is conducted in Asia, Europe and South America. The aim of this research is to compare the efficacy (reduction in HbA1c and blood glucose) and pulmonary safety (pulmonary function tests, chest x-rays) of mealtime inhaled insulin with subcutaneous insulin aspart both in combination with insulin detemir in Type 2 Diabetes.

NCT ID: NCT00329108 Terminated - Clinical trials for Bipolar Disorder, Manic

Ziprasidone And Olanzapine's Outcomes In Mania

ZOOM
Start date: November 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy and tolerability of ziprasidone versus olanzapine in the treatment of acute mania. An open label extension will further evaluate the efficacy, safety, and tolerability of ziprasidone compared with olanzapine. Study recruitment was stopped due to difficulty in enrolling the targeted number of patients on July 30, 2007. Subjects that were enrolled at the time completed the study as per protocol. There were no safety concerns involved in the decision to stop enrollment. The Last Subject Last Visit was January 10, 2008.

NCT ID: NCT00327470 Terminated - Clinical trials for Macular Degeneration

An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD

PERSPECTIVES
Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the benefits of treating subjects with neovascular age-related macular degeneration (AMD) at an earlier stage of choroidal neovascularization (CNV) as compared to those with established CNV. Additionally, the study would like to determine the efficacy of Macugen in preserving visual function in those subjects having CNV secondary to neovascular AMD.

NCT ID: NCT00327379 Terminated - Clinical trials for Blood Loss, Surgical

Effect of Aprotinin on Transfusion Requirements in Patients Undergoing Elective Spinal Fusion Surgery

Start date: February 27, 2006
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety and efficacy of aprotinin as compared to placebo, in reducing the need for blood transfusion in adult subjects undergoing elective spinal fusion surgery involving 3 to 7 vertebral levels with instrumentation

NCT ID: NCT00325000 Terminated - Major Depression Clinical Trials

Interpersonal Psychotherapy for Severely Depressed Inpatients

Start date: November 2000
Phase: N/A
Study type: Interventional

We examined the hypotheses that severely depressed inpatients treated for 5 weeks with IPT-S plus pharmacotherapy have 1) a higher reduction in depressive symptoms and 2) higher response- and remission rates compared to pharmacotherapy plus CM. For the follow-up period (12 months) we hypothesized a better symptomatic and psychosocial longterm outcome and lower rates of relapse for patients initially treated with combination therapy.

NCT ID: NCT00322803 Terminated - Panic Disorder Clinical Trials

ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment

Start date: May 2006
Phase: Phase 2
Study type: Interventional

This study is designed to investigate if 600 mg ELB139 given orally t.i.d. to patients suffering from panic disorder is effective in reducing anxiety evoked by inhalation of 35% CO2 measured by a visual analogue scale after the first intake and after approximately one week of treatment as compared to placebo treatment.

NCT ID: NCT00322218 Terminated - Clinical trials for Lymphoma, Large Cell, Diffuse

Study Comparing Zevalin Regimen With no Further Treatment in Patients With Diffuse Large B-cell Lymphoma.

Start date: May 2006
Phase: Phase 3
Study type: Interventional

This study treats patients with diffuse large B-cell lymphoma whose disease is in complete remission due to previous treatment with Cyclophosphamide Doxorubicin hydrochloride Vincristine Prednisolone- Rituximab (CHOP-R). Half of the patients received Zevalin and the other half receive no further anti-cancer treatment. The two patient groups compared to determine if Zevalin given after CHOP-R therapy provides greater benefits than receiving no additional anti-cancer therapy after CHOP-R.

NCT ID: NCT00322036 Terminated - Alzheimer Disease Clinical Trials

Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's

Start date: May 2006
Phase: Phase 3
Study type: Interventional

This is a multinational, randomized, double blind, placebo controlled, parallel group study comparing the safety and efficacy of daily dosing of 800 mg twice daily MPC-7869 to placebo. Study subjects will have the diagnosis of mild dementia of the Alzheimer's type. Subjects may be taking approved medication for Alzheimer's disease provided the dose has been stable for at least 6 months.

NCT ID: NCT00321308 Terminated - Clinical trials for Carcinoma, Non-Small Cell Lung

Trial of Pemetrexed With or Without PF-3512676 in Advanced Non-Small Cell Lung Cancer

Start date: September 2006
Phase: Phase 2
Study type: Interventional

To assess the efficacy and safety of PF-3512676 administered in combination with pemetrexed for the treatment of patients with locally advanced or metastatic NSCLC who have failed one prior chemotherapy regimen

NCT ID: NCT00320190 Terminated - Clinical trials for Leukemia, Myeloid, Chronic

Study of Dasatinib in Patients With Chronic Phase Chronic Myeloid Leukemia and a Suboptimal Response to Imatinib

Start date: August 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the efficacy of dasatinib with that of high-dose (800-mg) imatinib in participants with chronic phase chronic myeloid leukemia who achieved only a suboptimal response after at least 3 months of monotherapy with 400-mg imatinib. The safety of these treatments will also be evaluated.