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NCT ID: NCT04960475 Active, not recruiting - Clinical trials for Chronic Ankle Sprain

Study of Negative Emotion, Fear-Avoidance Belief and Quality of Life in Patients With Ankle Sprain

Start date: January 1, 2021
Phase:
Study type: Observational

This study intends to investigate the negative emotions, fear-avoidance beliefs, and quality of life in patients with chronic ankle sprains to explore the relationship between negative emotions such as anxiety and depression, fear-avoidance beliefs, and their impact on quality of life.

NCT ID: NCT04958382 Active, not recruiting - Chronic Insomnia Clinical Trials

Study for Evaluating the Efficacy of Ciprofol in Patients Under Narcotic Sleep With Chronic Insomnia

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

This is a single center, randomized, single blind, exploratory clinical study.About 30 patients with chronic insomnia are planned to be enrolled in this study and randomized into two groups by a ratio of 4:1 (Figure 1), with group 1 (24 subjects) for ciprofol and group 2 (6 subjects) for placebo (fat emulsion). Cognitive behavioral therapy (CBT) will be given to these patients during the treatment.

NCT ID: NCT04957888 Active, not recruiting - Clinical trials for Acute Gastrointestinal Injury

Microbial Markers for AGI

Start date: July 1, 2020
Phase:
Study type: Observational

AGI is very common in ICU and sometimes will trigger the development of gut derived sepsis. Thus, to find out the biomarker in early stage is very important to improve the overall prognosis of critically ill patients. In this project we try to find out the microbial biomarker of AGI through multi-omic technology.

NCT ID: NCT04956432 Active, not recruiting - Gout Clinical Trials

A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout

Start date: June 15, 2021
Phase: Phase 3
Study type: Interventional

This study will assess the serum uric acid lowering effects and safety of SHR4640 compared to Allopurinol in subjects with gout.

NCT ID: NCT04956419 Active, not recruiting - Clinical trials for Acute Vulvovaginal Candidiasis

A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Acute Vulvovaginal Candidiasis

Start date: April 24, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole In Subjects with Acute vulvovaginal Candidiasis

NCT ID: NCT04954131 Active, not recruiting - COVID-19 Clinical Trials

Immunogenicity and Safety Study of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adultsin China

Start date: August 10, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this clinical study, CLO-SCB-2019-010, is to assess the immunogenicity, reactogenicity and safety of the SCB-2019 vaccine in Chinese participants, and to show the comparability of the immune response versus randomly selected individuals who participated in the large-scale efficacy study with the SCB-2019 vaccine (Study CLO-SCB-2019-003).

NCT ID: NCT04954001 Active, not recruiting - Neurofibromatosis 1 Clinical Trials

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

Start date: March 26, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

FCN-159 is a highly active MEK1/2 inhibitor that was designed, synthesized and screened on the basis of the structure of trametinib. FCN-159 is an orally available and highly potent selective inhibitor of MEK1/2, which is expected to be a targeted therapy for the treatment of advanced solid tumors and neurofibromatosis type 1.

NCT ID: NCT04951440 Active, not recruiting - Clinical trials for Acute Ischemic Stroke

Study on the Effectiveness and Safety of Nitrone for Injection in Patients With Acute Ischemic Stroke

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The main purpose of the study: To evaluate the effect of nitrosone 1 special for patients with acute ischemic cerebral stroke. The secondary purpose of the study: To evaluate the effectiveness of the injection of nitrosone I. T for loyal patients with acute ischemic stroke All women think.

NCT ID: NCT04951050 Active, not recruiting - Clinical trials for Coronary Artery Disease

TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatment

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Start date: February 28, 2022
Phase: N/A
Study type: Interventional

The aim of the TARGET PREMIER trail in to demonstrate the safety and efficacy of the rapamycin target eluting stent in the treatment of subjects with ischemic heart disease (asymptomatic myocardial ischemia , table or unstable angina), with target lesion(s) in coronary arteries with visually estimated reference vessel diameter ≥2.25mm and ≤4.0 mm.

NCT ID: NCT04950322 Active, not recruiting - Clinical trials for Gastric or Gastroesophageal Junction Cancer

A Trial of SHR1701 Plus Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Start date: December 6, 2021
Phase: Phase 3
Study type: Interventional

This study is a randomized, Double-Blind, multi-center Phase III clinical study, aimed to evaluate the efficacy and safety of SHR1701 combined with chemotherapy in the treatment of Previously Untreated, Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer. For Part 1 study,the tolerability of SHR-1701 will be evaluated and determine the recommended dose for Part 2.For Part 2 study, all enrolled patients will be randomized to 2 groups and continuously treated until the end criteria of treatment was met.