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NCT ID: NCT04944641 Recruiting - Epilepsy Clinical Trials

Epilepsy Prevalence and Intervention Study in Zhejiang Province, China

Start date: September 13, 2013
Phase: N/A
Study type: Interventional

To carry out the epidemiological investigation on epilepsy in Zhejiang Province, China, and then establish early comprehensive intervention to help patients with epilepsy to improve seizure control and the quality of life.

NCT ID: NCT04944615 Recruiting - Clinical trials for Chronic Total Occlusion of Coronary Artery

To Evaluate Whether IVUS-guided Drug-eluting Stent (DES) Implantation Leads to Better Clinical Outcomes Compared to Conventional Angiography in the Treatment of Chronic Complete Occlusion (CTO) Disease.

CRUISE-CTO
Start date: October 21, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the treatment of Chronic total occlusion (CTO) disease. Whether Intravascular Ultrasonography (IVUS) guiding the implantation of drug-eluting stents (DES) will provide better long-term clinical outcomes compared with conventional angiography

NCT ID: NCT04944563 Recruiting - Surgery Clinical Trials

Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field

Start date: July 20, 2021
Phase: N/A
Study type: Interventional

This study aims to investigate whether segmentectomy had non-inferiority long-term oncological effects (disease-free survival and overall survival) compared with lobectomy in the treatment of patients with early-stage non-small cell lung cancer ≤ 2 cm in the middle third of lung field.

NCT ID: NCT04944524 Recruiting - Clinical trials for Granulomatosis With Polyangiitis

Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA

Start date: July 1, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to identify the optimal maintenance therapy for granulomatosis with polyangiitis (GPA) by comparing the MTX (standard regimen) with Tofacitinib in terms of efficacy, i.e. in preventing relapses.

NCT ID: NCT04943939 Recruiting - Clinical trials for Postoperative Delirium

Correlation of Electroencephalogram With Postoperative Delirium During Cardiac Surgery

Start date: July 1, 2020
Phase:
Study type: Observational

The purpose of this study is to explore characteristic changes of EEG epileptiform discharges in patients under CPB and correlation with POD

NCT ID: NCT04943913 Recruiting - Glioma Clinical Trials

Study on TIL for the Treatment of Brain Glioma

Start date: May 6, 2021
Phase: Early Phase 1
Study type: Interventional

This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with malignant glioma . Autologous TILs are expanded from tumor resections and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide.

NCT ID: NCT04943783 Recruiting - Clinical trials for Inflammation Vascular

Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms

ATREAT-VBD
Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This study was designed to whether there is a measurable reduction in inflammation in walls of unruptured vertebrobasilar dissecting aneurysms with atorvastatin.

NCT ID: NCT04943718 Recruiting - Malignant Glioma Clinical Trials

Personalized Vaccine for Patients With Recurrent Malignant Glioma

Start date: July 15, 2021
Phase: Phase 1
Study type: Interventional

A single-arm, single-center, open-labeled study will be conducted with an aim to investigate the feasibility, safety, and efficacy of the personalized vaccine for patients with recurrent malignant glioma.

NCT ID: NCT04943679 Recruiting - Clinical trials for Hepatocellular Carcinoma

Anti-PD-1/PD-L1 Antibodies Plus Pegylated Interferon Alfa-2b Treatment in Patients With Advanced-Stage HCC

Start date: June 15, 2021
Phase:
Study type: Observational

This study is being done to analyze the safety, tolerability, and efficacy of treatment using combination of Pegylated Interferon Alfa-2b and anti-PD-1/PD-L1 antibodies for patients with advanced hepatocellular carcinoma.

NCT ID: NCT04943146 Recruiting - Thyroid Diseases Clinical Trials

An Assessment of Aspirin Plus Prednisone Treatment for Euthyroid Women With Thyroid Autoimmunity

Start date: March 1, 2021
Phase:
Study type: Observational

Thyroid autoimmunity(TAI) per se have adverse effect on pregnancy outcomes,and aspirin and prednisone were used frequently in antithyroid antibodies(ATA) positive infertile women in clinical practice, but the impact of these medicines is still controversial. Therefore, aim of the study was to investigate whether or not the treatment of prednisone in addition to aspirin was capable of improving reproductive outcomes in euthyroid infertile women.