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NCT ID: NCT04957459 Recruiting - Macular Holes Clinical Trials

The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes

Start date: January 1, 2020
Phase:
Study type: Observational

This study retrospectively analyzed the relationship between the preoperative optical coherence tomography(OCT) and optical coherence tomography angiography(OCTA) software related parameters of patients with idiopathic macular hole, the patient's own clinical data and the best corrected visual acuity (BCVA) for at least one month after surgery.

NCT ID: NCT04957420 Recruiting - Parkinson's Disease Clinical Trials

The Practical Effect of Neupro

Start date: July 1, 2021
Phase:
Study type: Observational

This is a multicenter, prospective, non intervention post marketing surveillance study conducted in Chinese mainland. The main objective was to evaluate the safety characteristics of rotigotine patch in the treatment of Chinese adult patients with idiopathic Parkinson's disease in real world clinical practice.

NCT ID: NCT04957407 Recruiting - Gastric Cancer Clinical Trials

The Research of Constructing a Risk Assessment Model for Gastric Cancer Based on Machine Learning

Start date: January 1, 2019
Phase:
Study type: Observational

Based on the gastric cancer database established earlier, this project explored the PG standard suitable for Chinese people, and further explored the establishment of machine learning model to stratify gastric cancer risk in the population, guide the frequency of gastroscopy screening, and extract important gastric cancer risk factors from it.Establish electronic health records of gastric organs, track the development and outcome of gastric diseases through deep learning method, in order to predict the development and outcome of gastric diseases;Then, the simulation hypothesis deductive method is used to compare the outcomes that may be caused by different lifestyles with the help of deep learning model, so as to guide patients to develop a better lifestyle and explore the establishment of health management paths for gastric cancer patients and high-risk groups in China.

NCT ID: NCT04957056 Recruiting - Intraspinal Tumor Clinical Trials

Finite Element Study of Biomechanical Changes After Unilateral Hemilamina and Facet Joint Resection of Cervical Spine

Start date: February 1, 2018
Phase:
Study type: Observational

Finite element method was used to simulate unilateral hemilaminectomy of cervical spine and facet joint resection of different degrees, and the range of motion and the stress changes of ligament, intervertebral disc and endplate were calculated immediately after operation

NCT ID: NCT04956926 Recruiting - Clinical trials for Patients With Advanced Malignant Tumors

Clinical Study of JS201 in Patients With Advanced Malignant Tumors

Start date: July 29, 2021
Phase: Phase 1
Study type: Interventional

This is an open label, phase I clinical study to evaluate the safety, tolerability, pharmacokinetic (PK) profile, pharmacodynamic (PD) profile, immunogenicity and preliminary efficacy of JS201 in the patients with advanced malignant tumors who have progression after or during the standard of care, or no effective standard therapeutic regimen. This study is divided into three phases: dose-escalation phase, dose expansion phase, and clinical expansion phase.

NCT ID: NCT04956822 Recruiting - Clinical trials for Amyotrophic Lateral Sclerosis

Application of Motor Unit Estimation Index in Amyotrophic Lateral Sclerosis and Related Diseases

Start date: June 1, 2018
Phase:
Study type: Observational

This was a cross-sectional study in which patients were divided into 20 patients with amyotrophic lateral sclerosis, 20 patients with peroneal muscular dystrophy, 20 patients with Kennedy's disease and 30 healthy controls, in which patients with amyotrophic lateral sclerosis continued to be followed up for 1 year and the results of 4 cross-sectional examinations were taken.

NCT ID: NCT04956679 Recruiting - Family Clinical Trials

Family-based Screening and Treatment of Helicobacter Pylori:A Real World Study

Start date: July 10, 2021
Phase:
Study type: Observational [Patient Registry]

The habit of family meals makes the infection rate of Helicobacter pylori high in China, which is also the main cause of reinfection of Helicobacter pylori. Eating together can easily cause family members to be infected with Helicobacter pylori. We used a real-world study to understand the risk factors, epidemiological characteristics, and safety and effectiveness of eradication therapy for helicobacter pylori infection in family-based screening and treatment.

NCT ID: NCT04956328 Recruiting - Clinical trials for Primary Biliary Cirrhosis

Study of Obeticholic Acid(OCA) Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)

Start date: July 22, 2021
Phase: Phase 3
Study type: Interventional

Obecholic acid is a modified bile acid and Farnesoid X receptor (FXR) agonist. FXR is a key regulator of bile acid synthesis and transport. Bile acids are used by the body to help with digestion. Conventional therapy with obecholic acid will improve liver function of patients with PBC.

NCT ID: NCT04956146 Recruiting - Clinical trials for Carcinoma, Non-Small-Cell Lung

Fruquintinib Combined With Sintilimab and Chemotherapy in the Treatment of Non-Small Cell Lung Cancer

Start date: February 2, 2022
Phase: Phase 2
Study type: Interventional

A phase II study to assess the efficacy and safety of Fruquintinib Combined With Sintilimab and Chemotherapy as a first-line treatment in patients with unresectable or metastatic advanced Wild-type Genotype non-squamous Non-small Cell Lung Cancer.

NCT ID: NCT04955834 Recruiting - Type 2 Diabetes Clinical Trials

A Clinical Study of Insulin Degludec Injection in Subjects With Type 2 Diabetes

Start date: July 27, 2021
Phase: Phase 3
Study type: Interventional

This study is a multi-center, randomized, open-label, parallel, positive-controlled registered clinical study,to evaluate the efficacy and safety of insulin degludec injection developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd.