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NCT ID: NCT04962438 Recruiting - Clinical trials for Endothelial Dysfunction

Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function

Start date: July 5, 2019
Phase:
Study type: Observational

Explore the effects of anti-VEGF targeted drugs on blood pressure and endothelial function in cancer patients.

NCT ID: NCT04962425 Recruiting - Breast Cancer Clinical Trials

Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients

Start date: January 8, 2021
Phase:
Study type: Observational

According to the existing clinical data in our hospital, retrospective study was conducted to screen the risk factors with predictive value for TRC(trastuzumab-related cardiotoxicity) risk, and to construct the risk prediction model for TRC.

NCT ID: NCT04962412 Recruiting - Critical Illness Clinical Trials

Predicting Poor Outcomes of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers

Start date: May 12, 2021
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to identify and validate novel biomarkers including functional tests for detecting AKI, AKI progression and other poor outcomes.

NCT ID: NCT04962386 Recruiting - Clinical trials for Meibomian Gland Dysfunction

Clinical Efficacy of Hormone Replacement Therapy in Treating Perimenopausal Women With MGD

Start date: March 6, 2019
Phase:
Study type: Observational

This project aims to evaluate the possible relationship between MGD and HRT in perimenopausal women

NCT ID: NCT04962308 Recruiting - COVID-19 Clinical Trials

Clinical Trial of Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Healthy Adults

Start date: June 19, 2021
Phase: Phase 4
Study type: Interventional

This study is an open-label phase Ⅳ clinical trial of the inactivated SARS-CoV-2 vaccine(CoronaVac)manufactured by Sinovac Research & Development Co., Ltd. The purpose of this study is to evaluate the immunogenicity and safety of the Inactivated SARS-CoV-2 Vaccine (Vero Cell) in Healthy Population Aged From 18 to 59 Years.

NCT ID: NCT04962295 Recruiting - Clinical trials for Cerebral Small Vessel Diseases

China Imaging-based Biobank of Cerebral Small Vessal Diseases

Start date: October 1, 2020
Phase:
Study type: Observational

The purpose of this study is to build a national image-based comprehensive evaluation platform of CSVD through longitudinal collection of imaging based medical data of patients with cerebral small vessel diseases (CSVD). On this basis, the new classification and diagnostic criteria of CSVD are proposed, and the risk prediction model of CSVD is established. By evaluating the prognostic factors of CSVD, early identification of high-risk CSVD population.

NCT ID: NCT04962282 Recruiting - Clinical trials for Non-specific Chronic Low Back Pain

Research on Influencing Factors of Compliance of Spinal Exercise Therapy

Start date: January 1, 2019
Phase:
Study type: Observational

Explore the many factors that affect the compliance of home exercise therapy in patients with non-specific chronic low back pain, establish a theoretical model of the factors affecting compliance behavior, in order to guide rehabilitation clinical practice, and improve the compliance of patients with non-specific chronic low back pain to home exercise prescriptions.

NCT ID: NCT04962178 Recruiting - Clinical trials for ST-segment Elevation Myocardial Infarction (STEMI)

Evaluate Early Invasive Strategy for Patients With STEMI Presenting 24-48 Hours From Symptom Onset

Start date: September 9, 2021
Phase: N/A
Study type: Interventional

The primary objective of the trial is to evaluate the efficacy of early invasive strategy for STEMI patients within 24-48h of symptom onset.

NCT ID: NCT04961996 Recruiting - Early Breast Cancer Clinical Trials

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

Start date: August 27, 2021
Phase: Phase 3
Study type: Interventional

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with endocrine therapy of physician's choice in participants with medium- and high-risk Stage I-III histologically confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative early breast cancer. In addition, an open-label exploratory substudy will explore the safety and efficacy of giredestrant in combination with abemaciclib in a subset of the primary study population.

NCT ID: NCT04961970 Recruiting - Clinical trials for Intrahepatic Cholangiocarcinoma

HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICC

Start date: July 9, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin, 5-fluorouracil and leucovorin compared systemic chemotherapy of gemcitabine and cisplatin in patients with unresectable intrahepatic cholangiocarcinoma.