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NCT ID: NCT04963959 Recruiting - Clinical trials for Peripheral Blood Mononuclear Cell

PBMC Collection for Production of UCAR T Cells

Start date: July 14, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to collect peripheral blood mononuclear cells (PBMC) from healthy volunteers for the research and production of UCAR T cells used for Clinical trails.

NCT ID: NCT04963621 Recruiting - Emotional Stress Clinical Trials

RCT of CESIP for Children With Emotional and Stress Problems

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

To explore the effect of Child-Adolescent Emotion and Stress Intervention Program for children with emotional and stress problems, providing early social psychological intervention for aiming the core impairments of emotional and stress problems.

NCT ID: NCT04963361 Recruiting - Clinical trials for Total Knee Arthroplasty

Study on Fear of Movement After Total Knee Arthroplasty

Start date: March 25, 2021
Phase:
Study type: Observational

Total knee arthroplasty is one of the effective methods for the treatment of end-stage osteoarthritis. Postoperative rehabilitation exercise is an important method for the recovery of knee joint function. Exercise fear refers to an enlarged psychological phenomenon that patients are afraid of sports leading to injury, which is not conducive to the functional exercise of patients and hinders the recovery of knee joint function

NCT ID: NCT04963257 Recruiting - OCD Clinical Trials

Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive Disorder

Start date: January 1, 2020
Phase: Phase 4
Study type: Interventional

To verify that sertraline combined with fluvoxamine is superior to sertraline combined with aripiprazole

NCT ID: NCT04963101 Recruiting - Transcriptome Clinical Trials

RNA-seq Analysis of PBMC in Patients With OPLL

Start date: June 25, 2021
Phase:
Study type: Observational

In this study, we planned to identify transcriptome expression profiles (circRNAs, lncRNAs, and mRNAs) from peripheral blood mononuclear cells (PBMCs) of 30 patients with OPLL and 30 other non-OPLL patients by high-throughput sequencing.Sequence analysis was used to predict miRNAs that might bind circRNAs and lncRNAs.Through bioinformatics analysis, competitive endogenous RNAs (cerRNAs), as well as coexpression networks among circRNAs, lncRNAs, miRNAs, and mRNAs, were constructed to provide key molecules and signaling pathways associated with OPLL.

NCT ID: NCT04963088 Recruiting - Gastric Cancer Clinical Trials

TISLELIZUMAB Combined With Anlotinib and Chemotherapy(XELOX) in the Treatment of Advanced Gastric Carcinoma

TAXE-GC
Start date: March 6, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 2, multi-cohort study to investigate safety, anti-tumor activity of the monoclonal antibody BGB A317 in combination with Anlotinib and standard chemotherapy as first-line treatment in Gastric, or Gastroesophageal Junction Carcinoma. The study includes a screening (up to 28 days), treatment (until disease progression, intolerable toxicity, or treatment withdrawal for another reason), safety follow-up (up to 30 days following last study drug treatment), and survival follow-up phase.

NCT ID: NCT04963010 Recruiting - Clinical trials for Adenoma Detection Rate

Impact of SFV of Proximal Colon on ADR

Start date: June 14, 2021
Phase: N/A
Study type: Interventional

To evaluate the impact of second forward view examination of the proximal colon on adenoma detection rate Inclusion criteria:Patients ≥18 years of age undergoing screening, follow-up monitoring, and diagnostic colonoscopy Exclusion criteria:①Cecal intubation failed. ②Have a history of colorectal surgery. ③Insufficient bowel preparation, inadequate bowel preparation quality (Boston Bowel Preparation Scale (BBPS)scores < 2 in any segment of the colon). ④Inflammatory bowel disease or intestinal tuberculosis. ⑤Familial polyp syndrome. ⑥polyp retrieval failure. ⑦Patients with coagulation dysfunction. Patients ≥ 18 years of age who came to our hospital's Digestive Endoscopy Center for screening, follow-up monitoring and diagnosis of colonoscopy. After successfully insert the cecum, colonoscope withdrawal to the splenic flexure, all polyps found during the withdrawal process were resection,then they were randomized to standard withdrawal colonoscopy or second forward view according to the random number table (1:1) to perform.

NCT ID: NCT04962945 Recruiting - Clinical trials for Central Venous Catheterization

Comparison of the Oblique-axis and Long-axis Approaches for Axillary Vein Catheterization Under Ultrasound Guidance

Start date: July 6, 2021
Phase: N/A
Study type: Interventional

Ultrasound-guided axillary vein catheterization can be performed via the oblique-axis and long-axis approaches of the axillary vein. The aim of our study is to compare the first puncture success rate and safety between the two approaches of ultrasound-guided axillary vein catheterization in cardiac surgical patients with high bleeding risk

NCT ID: NCT04962763 Recruiting - Clinical trials for To Search for Biomarkers Associated With Ischemic Heart Failure

Correlation of Intestinal Flora and Metabolomics in Patients With Ischemic Heart Failure

Start date: June 30, 2021
Phase:
Study type: Observational

To provide new ideas for the treatment of patients with ischemic heart failure, this study is to search for differential metabolic markers associated with ischemic heart failure and to study the influence of fecal flora on the course of heart failure in patients with ischemic heart failure.

NCT ID: NCT04962555 Recruiting - Meniscus Injury Clinical Trials

Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

Start date: August 1, 2016
Phase:
Study type: Observational

Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender difference and ratio of medial and lateral meniscus injuries. Differences, differences in locations, differences in tearing methods, differences in surgical methods, and the course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection, subtotal resection and meniscus regeneration after total resection, imaging and secondary arthroscopic exploration (Second-Look) were studied.