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NCT ID: NCT05691881 Recruiting - Cancer Clinical Trials

68Ga-labeled NY105 PET Imaging in Patients

Start date: September 28, 2022
Phase: Early Phase 1
Study type: Interventional

This is a single arm study to evaluate the safety and biodistribution of 68Ga-labeled NY105 PET Imaging in patients

NCT ID: NCT05691855 Recruiting - Cancer Clinical Trials

89Zr-labeled NY009 PET Imaging in Patients

Start date: June 1, 2022
Phase: Early Phase 1
Study type: Interventional

This is a single arm study to evaluate the safety and biodistribution of 89Zr-labeled NY009 PET Imaging in patients

NCT ID: NCT05691712 Active, not recruiting - Diabetes Mellitus Clinical Trials

A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes

SURPASS-CN-INS
Start date: February 5, 2023
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to compare the effect of the addition of tirzepatide or placebo to titrated basal insulin on glycemic control in Chinese participants with type 2 diabetes.

NCT ID: NCT05691621 Recruiting - Sepsis Clinical Trials

Galectin-3 in Septic and Non-septic Acute Kidney Injury

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

Acute kidney injury (AKI) is a common critical condition with high morbidity and mortality. The level of circulating Galectin-3 (Gal3) largely depends on renal function, so it is elevated in patients with AKI or CKD; elevated Gal3 also aggravates the progression of CKD after the onset of AKI. The proinflammatory and profibrotic properties of Gal3 may render it to be one of the key molecules mediating AKI, CKD, and cardiorenal syndrome. In this prospective observational study, the investigators will explore the differences of Gal3 levels among septic AKI, non-septic AKI, and non-AKI patients and its correlation with prognosis, inflammation, and disease severity in the ICU.

NCT ID: NCT05691296 Active, not recruiting - Myopia Clinical Trials

The Monitoring and Intervention of Refractive Changes in Children and Teenagers in Tianjin

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The study aimed to collect multi-factor information on school-age children with pre-clinical myopia, and to identify the initial factors and warning signs of myopia.

NCT ID: NCT05691179 Recruiting - Clinical trials for Idiopathic Membranous Nephropathy

COVID-19 Infection and Idiopathic Membranous Nephropathy

Start date: December 10, 2022
Phase:
Study type: Observational [Patient Registry]

Infection is one of common risk factors for relapsing of idiopathic membranous nephropathy (IMN). However, it is still unclear wheather COVID-19 infection can induce the relapsing of IMN. Herein, in this prospective, multi-center, cohort study, the investigator enrolled the IMN patients with COVID-19 infection. All subjects will be followed for three months with four visits at 1, 2 and 3 months. Then the investigator will compare the rate of replase of IMN in the two groups to evaluate the association of COVID-19 infection and replapse of IMN.

NCT ID: NCT05691153 Recruiting - B Cell Lymphoma Clinical Trials

ThisCART19A for B-NHL Relapsed After Auto-CAR T

Start date: December 1, 2022
Phase: Phase 1
Study type: Interventional

This is a phase 1, single-center, dose selection study to evaluate the efficacy, safety, and pharmacokinetics of ThisCART19A (allogeneic CAR-T targeting CD19) in patients with Auto-CAR T relapsed B-cell non-Hodgkin's lymphoma.

NCT ID: NCT05691114 Recruiting - Clinical trials for Idiopathic Parkinson's Disease

Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's Disease

Start date: February 2023
Phase: Phase 1
Study type: Interventional

This is a single-center, single-arm, dose escalation study, to explore the safety, tolerability and efficacy of human amniotic epithelial stem cells (hAESCs) for idiopathic Parkinson's disease (PD).

NCT ID: NCT05691088 Recruiting - Clinical trials for Acetaminophen,Mechanical Ventilation,Critically Ill Children

Clinical Efficacy of Acetaminophen in Mechanical Ventilation in Children With New Coronary Pneumonia

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

Patients were randomized to receive either paracetamol during mechanical ventilation. When patients were randomized to receive paracetamol (40 mg/kg per day in 4 doses), a placebo infusion of normal saline was administered continuously at the same rate as an equivalent infusion. Placebos could not be distinguished from the active study drug in color, odor, or viscosity. In both study groups, IMV was maintained with sufentanil (0-0.2 mcg/kg/h), propofol (0-4 mg/kg/h), and dexmedetomidine (0-1 mcg/kg/h). Assessment of sedation levels by the bedside nurse using the FLACC pain scale to determine if the child is adequately comfortable or in need of more or less medication to maintain adequate ventilation. Assessment of sedation levels by the bedside nurse using the FLACC pain scale (every 6 hours as a minimum time interval).

NCT ID: NCT05690906 Recruiting - Clinical trials for Uterine Cervical Neoplasms

Evaluate the Effect of ReSpaceā„¢ Hydrogel on Reducing Rectal Radiation Dose in Radiotherapy for Cervical Cancer

Start date: July 12, 2022
Phase: Phase 2
Study type: Interventional

This phase II clinical study plan to recruit 100 subjects, 1:1 divide them into experimental group and control group, and the cumulative D2cc dose for rectum during brachytherapy will be recorded and compared.