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NCT ID: NCT05360875 Recruiting - Endometriosis Clinical Trials

The Effect of Endometrial Scratching on Patients With Endometriosis

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

We aimed to investigate whether endometrial scratching could improve IVF outcomes by enhancing endometrial receptivity in patients with endometriosis.

NCT ID: NCT05360446 Recruiting - Clinical trials for Coronary Artery Disease

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

V-PLAQUE
Start date: July 8, 2022
Phase: Phase 3
Study type: Interventional

CKJX839D12303 is a research study to determine if the study treatment, called inclisiran, in comparison to placebo taken in addition to statin medication can effectively reduce the total amount of plaque formed in the heart's vessels as measured by coronary computed tomography angiography (CCTA) from baseline to month 24. This study is being conducted in eligible participants with a diagnosis of non-obstructive coronary artery disease (NOCAD), where the coronary arteries are blocked less than 50%, and with no previous cardiovascular events.

NCT ID: NCT05360420 Recruiting - Liver Cancer Clinical Trials

Diagnosis of Nodules ≤2 cm Based on US and CEUS Compared With Current Clinical Procedure

Start date: October 26, 2022
Phase: N/A
Study type: Interventional

Due to different etiologies, diagnosis and treatment of HCC in China is different from that in Western countries.US is an important screening method for HCC in patients with liver cirrhosis. CEUS, as an enhanced imaging method based on US, has the advantages of convenience, non-radiation, low cost, short examination time, and the diagnostic performance of HCC is comparable to that of CECT, CEMRI, and hepatobiliary-specific MRI. It is of great significance to consider the cost-effectiveness of each examination based on the principle of cost minimization. Therefore, we propose immediate CEUS examination for suspicious lesions ≤2 cm screened by US, and determine the diagnostic process of further diagnostic methods based on the CEUS results. The aim of this study is to establish a screening and diagnosis process for HCC ≤2 cm suitable for China considering time effect, economic effect and diagnostic efficiency.

NCT ID: NCT05360290 Recruiting - Breast Cancer Clinical Trials

CTCs in Breast Cancer After Neoadjuvant Treatment and Surgery: a Multicenter, Prospective Clinical Trial

CTCNeoBC-E
Start date: September 14, 2022
Phase: N/A
Study type: Interventional

The GILUPI CellCollector® is the first in vivo CTC isolation product worldwide, which is CE approved. This is a prospective, multicenter study to evaluate the prognostic value of circulating tumor cells in breast cancer patients who completed surgery after neoadjuvant treatment.

NCT ID: NCT05360277 Recruiting - Clinical trials for Metastatic Colorectal Cancer,NED

Maintenance Tislelizumab + Capecitabine to Treat Metastatic Colorectal Cancer

CAMCO2
Start date: August 22, 2023
Phase: Phase 2
Study type: Interventional

Surgery with integrated treatment for metastatic colorectal cancer (mCRC) has created a new clinical setting known as mCRC with no evidence of disease (NED). However, these patients have a high risk of developing persistent cancer. This study aimed to investigate the efficacy and safety of Tislelizumab combined with capecitabine as a maintenance treatment for patients with mCRC-NED.

NCT ID: NCT05360251 Recruiting - Clinical trials for Erythematotelangiectatic Rosacea

Pulsed Dye Laser and Intense Pulsed Light Configured With Different Wavelength Bands in Improving Erythematotelangiectatic Rosacea

Start date: March 27, 2022
Phase: N/A
Study type: Interventional

Pulsed dye laser(PDL) and intense pulsed light(IPL) has been widely used in improving rosacea. To compare the efficacy and safety of PDL and IPL configured with different wavelength bands(Delicate Pulsed Light, M22 590, M22 vascular filter) in the treatment of rosacea, we designed a prospective, randomized controlled trial. We hope to make a comparison between PDL and IPL,between broad-spectrum IPL and narrow-spectrum IPL, between single-band IPL and dual-band IPL, and also provide clinical basis for clinicians and patients to develop individualized treatment plans.

NCT ID: NCT05360069 Recruiting - Clinical trials for Postoperative Complications

Linear Stapler Versus Circular Stapler in Esophagojejunostomy

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

With the development of stapler devices, various methods of esophagojejunostomy after laparoscopic total gastrectomy were evoluated. Which stapler is more advantageous has not been determined. At present, the most commonly used is linear stapler or Circular stapler in esophagojejunostomy. However, there is still a lack of reliable evidence for the selection of the two staplers. The purpose of this study is to explore the advantages of linear staper versus circular stapler in esophagojejunostomy for patients with gastric cancer who underwent total gastrectomy.

NCT ID: NCT05360043 Recruiting - Clinical trials for Enlarged Facial Pores

Efficacy and Safety of 1565-nm Non-ablative Fractional Laser Versus Long-pulsed 1064-nm Nd:YAG Laser in the Treatment of Enlarged Facial Pores

Start date: October 27, 2018
Phase: N/A
Study type: Interventional

Facial pores are visible openings of pilosebaceous follicles, it is one of the important factors that affect the appearance of facial skin. This study aims to evaluate and compare the Efficacy and safety of 1565 nm non-ablative fractional laser (NAFL) and long-pulsed 1064 nm Nd:YAG laser (LPNY) in the treatment of enlarged facial pores.

NCT ID: NCT05359796 Recruiting - Type 1 Diabetes Clinical Trials

Clinical Characteristics of People With Long-term Type 1 Diabetes

Start date: May 1, 2022
Phase:
Study type: Observational

Type 1 diabetes (T1D) is characterized by absolute insulin deficiency. Although the discovery and application of exogenous insulin has prolonged the lifespan of T1D patients, the chronic diabetic complications caused by long-term poor glycemic control will still reduce patients' quality of life and the overall life expectancy. According to the studies focused on long-term T1D, part of the patients with long disease duration showed resistance to microvascular complications, and several protective factors have been identified. The prevalence of T1D in China is extremely low compared to that in the western world, and little is known about the characteristics of patients with long-term T1D in China. Therefore, this study is designed to collect variable clinical and laboratory features of patients with long-term T1D, explore the risk and protective factors for the development of microvascular complications, and provide reference for the prediction and prevention of these complications.

NCT ID: NCT05359601 Recruiting - Critical Illness Clinical Trials

Infusion Set Replacement Intervals for Critically Ill Patients

Start date: May 15, 2022
Phase: N/A
Study type: Interventional

This study aimed to evaluate the efficacy of 24-hour versus 96-hour infusion set replacement to prevent central line-associated bloodstream infection (CLABSI) in critically ill adults with central venous access devices.