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NCT ID: NCT05603039 Recruiting - Clinical trials for Advanced Liver Cancer

A Phase Ib/II Trial to Evaluate the Safety and Efficacy of QL1706 in Patients With Advanced Hepatocellular Carcinoma

Start date: July 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase Ib/II trial to evaluate the safety, pharmacokinetics and preliminary efficacy of QL1706 or QL1604 combined with bevacizumab in patients with advanced hepatocellular carcinoma.

NCT ID: NCT05602922 Recruiting - Stroke Clinical Trials

Liu-Zi-Jue Exercise Combined With Conventional Rehabilitation Treat Dysphagia in Post-stroke

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

In this study, a prospective, randomized controlled method was adopted, with patients with post-stroke dysphagia as the main research objects, applying "Liu-Zi-Jue" to the patients for rehabilitation intervention, and to explore the effect of "Liu-Zi-Jue" on the swallowing function of patients with post-stroke dysphagia. In order to provide a safe and effective TCM treatment plan for patients with dysphagia after stroke, reduce the disability rate after stroke and improve the quality of life of patients.

NCT ID: NCT05602831 Recruiting - Clinical trials for Locally Advanced Cervical Cancer

Assessment of Prognosis Using Peripheral Blood Circulating Tumor DNA in Patients With Cervical Cancer

Start date: August 10, 2022
Phase:
Study type: Observational

This observational study is conducted to assess the value of using peripheral blood ctDNA to detect dynamic changes in HPV and genetic variants in predicting the prognosis of patients with locally advanced cervical cancer, as compared with traditional imaging and tumor markers.

NCT ID: NCT05602792 Recruiting - Breast Cancer Clinical Trials

A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors

Start date: April 21, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase I/IIa Study of the Safety and Tolerability of T3011 Administered via Intratumoral Injection in Patients with Advanced Solid Tumors

NCT ID: NCT05602714 Recruiting - Clinical trials for Cervical Disc Degeneration

Real World Data Collection and Analysis on the Anterior Cervical Spine Surgery

ACCSS
Start date: January 1, 2012
Phase:
Study type: Observational

This observational study aims to evaluate the efficacy and safety of anterior cervical spine surgery in patients with cervical degenerative disc disease

NCT ID: NCT05602480 Recruiting - Clinical trials for Pneumococcal Infections

Phase I Clinical Trial of a Candidate PCV13 in Healthy People

Start date: November 1, 2022
Phase: Phase 1
Study type: Interventional

Streptococcus pneumoniae is a major cause of morbidity and mortality in children worldwide, resulting in up to 1 million pediatric deaths every year. Since the licensure of PCV7, PCV10, PCV13 and PCV15, the reported overall decline in invasive pneumococcal disease in hospitalized children younger than 5 years is approximately 60% around the world. This is a single center, blinded, randomized, positive-controlled phase I clinical trial to evaluate the safety and explore the immunogenicity of a candidate PCV13 in healthy people aged 2 months (minimum 6 weeks) and above.

NCT ID: NCT05602415 Recruiting - Soft Tissue Sarcoma Clinical Trials

Anlotinib and Radiotherapy in Resectable Soft Tissue Sarcoma

Start date: November 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of dose reduced postoperative radiotherapy combined with Anlotinib for patients of soft tissue sarcoma

NCT ID: NCT05602311 Recruiting - Clinical trials for Postoperative Cognitive Dysfunction

Effects of General Anesthesia on Brain FC and Cognition in Children With Potential Neurological Damage

Start date: August 15, 2022
Phase:
Study type: Observational [Patient Registry]

Postoperative Cognitive Dysfunction(POCD)is a common postoperative complications, existing clinical research focused on the adult patients, ignoring that the developing human brain with underlying neurological impairments may be at higher risk for cognitive impairment, so we need a prospective study, observe this kind of "special groups" in the brain structure and function of before and after general anesthesia, To determine the susceptibility to neurotoxicity of general anesthesia drugs.

NCT ID: NCT05602051 Recruiting - Clinical trials for Hematologic Neoplasms

Mindfulness-based Virtual Reality Intervention

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Through virtual reality technology and mindfulness therapy, we can intervene the patients with Hematologic Neoplasms during chemotherapy, hoping to improve their symptoms and self-efficacy.

NCT ID: NCT05601895 Recruiting - Acute Leukemia Clinical Trials

The Gut Microbiome in FLT3- AL Undergoing Allo-HSCT With Or Without Sorafenib Maintenance

Start date: October 1, 2022
Phase:
Study type: Observational

This prospective trial investigates the effect of sorafenib maintenance therapy in FLT3 negative acute leukemia patients after allo-HSCT in terms of gut microbiome.