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NCT ID: NCT05624164 Recruiting - Rotator Cuff Tears Clinical Trials

Microfracture at Proximal Humerus Lateral to Footprint Could Enhance the Rotator Cuff Healing

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether there is any effect on rotator cuff healing by making microfracture at the lateral side of the footprint. The main question it aims to answer are: - [whether the lateralized microfracture could decrease the retear rate after arthroscopy rotator cuff repair.] - [whether the lateralized microfracture could improve the functional recovery after arthroscopy rotator cuff repair.] Participants with medium to larger size rotator cuff tears will be randomly assigned to the study group treated with lateralized microfracture immediately after arthroscopy rotator cuff repair or the control group treated with conventional arthroscopy rotator cuff repair without microfracture.

NCT ID: NCT05624099 Recruiting - Clinical trials for Esophageal Neoplasms

Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.

Start date: August 1, 2023
Phase: Phase 2
Study type: Interventional

This is a prospective single-arm exploratory clinical study. The efficacy and safety of camrelizumab combined with chemoradiotherapy and camrelizumab combined with chemotherapy were evaluated in patients with advanced esophageal cancer who had not previously received any systemic antitumor therapy for esophageal cancer.

NCT ID: NCT05623995 Recruiting - In-stent Restenosis Clinical Trials

Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)

Start date: December 15, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect of proprotein convertase subtilisin/kexin type-9 (PCSK9) inhibitors added to regular statin therapy on target lesion failure (TLF) and arteriosclerosis progression in patients with chronic total occlusions (CTOs) undergoing successful percutaneous coronary intervention (PCI).

NCT ID: NCT05623982 Recruiting - Clinical trials for Non-hodgkin's Lymphoma

Phase Ib/II Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Start date: September 26, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

To explore the safety and preliminary efficacy of GNC-038 in patients with relapsed or refractory NHL, and to determine the MTD and RP2D of GNC-038, or the MAD and DLT

NCT ID: NCT05623904 Recruiting - Clinical trials for Carotid Endarterectomy

Carotid Revascularization Versus Best Medical Treatment for Asymptomatic Carotid Stenosis

Start date: October 14, 2022
Phase: N/A
Study type: Interventional

This is a multicenter, open, randomized controlled trial to evaluate the efficacy and safety of carotid artery stenting/carotid endarterectomy versus best medical treatment for asymptomatic carotid artery stenosis in Chinese population.

NCT ID: NCT05623878 Recruiting - Prostatic Cancer Clinical Trials

68Ga-labeled NY108 PET Imaging in Patients

Start date: January 4, 2022
Phase: Early Phase 1
Study type: Interventional

This is a single arm study to evaluate the safety and biodistribution of 68Ga-labeled NY108 (68Ga-NY108) PET Imaging in patients.

NCT ID: NCT05623722 Recruiting - Sepsis Clinical Trials

Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury

Start date: December 29, 2022
Phase: N/A
Study type: Interventional

This study is a prospective, multicenter, parallel-group, open-label, randomized controlled clinical trial. Sepsis is defined as organ dysfunction induced by infections. And sepsis and gastrointestinal injury can be the leading cause for each other. Our previous study showed erector spinae plane block improved the organ dysfunctions in patients with AGI. The aim of the clinical trial is to investigate erector pinae plane block improves the organ dysfunction in septic patients with acute gastrointestinal injury.

NCT ID: NCT05623527 Recruiting - Stroke Clinical Trials

Acute Cerebrovascular Events Secondary to Patients Receiving Cardiac Electronic Implants

SOS-CARE
Start date: November 20, 2022
Phase:
Study type: Observational

Objective: To investigate the incidence, clinical characteristics and prognosis of acute ischemic and hemorrhagic cerebrovascular disease secondary to the implantation of cardiovascular implantable electronic devices, so as to provide a basis for subsequent treatment strategies and risk factor stratification. Methods: This study intends to retrospectively collect the incidence and case characteristics of acute cerebral infarction, cerebral embolism, transient ischemic attack and cerebral hemorrhage in CIED patients admitted to the First Affiliated Hospital of Xi 'an Jiaotong University and other centers from January 2012 to September 2022. Then, the incidence of poor prognosis and related factors of patients within 3 months were followed up by telephone to provide a basis for subsequent treatment strategy and risk factor stratification.

NCT ID: NCT05623384 Recruiting - Sudden Deafness Clinical Trials

Effect of Ultrasound-guided Stellate Ganglion Block Combined With Facial Nerve and Glossopharyngeal Nerve Block on the Treatment of Sudden Deafness

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

Sudden deafness is a sudden, unexplained sensorineural hearing loss of ≥20 dBHL in at least two adjacent frequencies within 72 h. It may be accompanied by tinnitus, a sense of ear congestion, vertigo and other Symptoms.Stellate ganglion block increases the blood flow and blood velocity in the inner ear, keeping the body's vegetative, endocrine and immune functions normal.The branches of the facial and linguopharyngeal nerves are connected to the inner ear, and local injection can nourish the nerves and improve local circulation.

NCT ID: NCT05623280 Recruiting - Breast Cancer Clinical Trials

Artificial Intelligence Analysis of Fluorescence Image to Intraoperatively Detect Metastatic Sentinel Lymph Node.

Start date: November 1, 2021
Phase:
Study type: Observational

The purpose of this study is to analysis the fluorescence image of the breast sentinel lymph node (SLN) using Indocyanine green (ICG). Moreover, to investigate whether an artificial intelligence protocol was suitable for identifying metastatic status of SLN during the surgery, and evaluate the diagnosis consistency of the AI technique and pathological examinations for lymph node with and without metastasis.