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NCT ID: NCT02989649 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

Start date: December 22, 2016
Phase:
Study type: Observational

The purpose of this study is to observe alogliptin and alogliptin fixed-dose combinations (FDCs) utilization patterns, as well as clinical response to treatment with alogliptin or alogliptin FDCs, in standard clinical practice.

NCT ID: NCT02985918 Terminated - Clinical trials for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

High-Intensity vs Low-Intensity NPPV in Patients With an AECOPD: The HAPPEN Trial

Start date: January 3, 2019
Phase: N/A
Study type: Interventional

To determine whether high-intensity NPPV, compared with low-intensity NPPV, could reduce the need for endotracheal intubation during hospitalization in patients with an AECOPD and hypercapnia.

NCT ID: NCT02985203 Terminated - Clinical trials for Lung Neoplasm Malignant

Oral Navelbine and Cisplatin Followed by Metronomic Oral Navelbine in Non-Small Cell Lung Cancer

Start date: November 2016
Phase: Phase 2
Study type: Interventional

This is an open-label, multi-center clinical trial, aims to evaluate the efficacy and safety of combination of oral Navelbine and Cisplatin followed by metronomic oral Navelbine in Patients with advanced Non-Small Cell Lung Cancer. The study comprises two stages. In the 1st stage (Week 1-12), all patients will receive combination chemotherapy. In the 2nd stage (Week 13-25), patients who complete the combination chemotherapy with acceptable tolerance and have no progressive disease (PD) will be allocated into 2 arms, to evaluate the efficacy and safety of maintenance chemotherapy with metronomic oral Navelbine (Arm A) or other regimen (Arm B).

NCT ID: NCT02982668 Terminated - Dysphagia Clinical Trials

Optimizing Early Enteral Nutrition in Severe Stroke

OPENS
Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this academic lead study is to explore the ideal nutritional support strategy for patient with acute severe stroke.

NCT ID: NCT02976766 Terminated - Optic Neuritis Clinical Trials

Gypenosides Treatment for Optic Neuritis

Start date: February 4, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether gypenosides are neuroprotective in patients with acute optic neuritis.

NCT ID: NCT02974426 Terminated - Radiotherapy Clinical Trials

To Evaluate the Optimal Timing of Postoperative Radiotherapy in Patients With IIIA(N2) Non-Small Cell Lung Cancer

Start date: November 2016
Phase: Phase 3
Study type: Interventional

Rationale: Completely resected non-small cell lung cancer (NSCLC) patients with histologically confirmed N2 disease are a heterogeneous population. After complete resection and postoperative chemotherapy (POCT), 20%-40% of cases have a risk of locoregional recurrence (LRR). Postoperative radiation therapy (PORT) should be an integral component of the multidisciplinary treatment for patients with stage IIIA(N2) disease. Postoperative Radiotherapy (PORT)-first strategy may have an advantage of the early administration of locoregional therapy to the mediastinum, in which the tumor burden is presumed to be higher than that of systematic micrometastases. It is not yet known for subsets with specific prognostic factors that confer higher LRR risks, what is the optimal timing of PORT and how to integrate with POCT (in a sequential fashion or concurrent fashion) when PORT is considered for patients with completely resected stage IIIA(N2) NSCLC. Purpose: This randomized phase III trial is studying the optimal timing of PORT to evaluate whether the PORT-first strategy (PORT administered first with concurrent or subsequent POCT) may be more effective than the PORT-last strategy (PORT administered sequentially following POCT) in treating high risk of LRR patients with completely resected pathologic stage IIIA(N2) NSCLC.

NCT ID: NCT02968784 Terminated - Prostate Cancer Clinical Trials

Focal ExAblate MR-Guided Focused Ultrasound Treatment for Management of Organ-Confined Intermediate Risk Prostate Cancer

Start date: June 2016
Phase: N/A
Study type: Interventional

This study is intended to show that ExAblateâ„¢ MRgFUS is a safe procedure that can significantly postpone or eliminate the need of patients with organ confined intermediate risk prostate cancer to undergo a definitive treatment (i.e., Radical Prostatectomy or Radiation therapy) for their disease.

NCT ID: NCT02955771 Terminated - Clinical trials for Hilar Cholangiocarcinoma

Efficacy and Safety Study of PDT Using Deuteporfin for Unresectable Advanced Perihilar Cholangiocarcinoma

Start date: May 17, 2017
Phase: Phase 2
Study type: Interventional

This is a multi-center, randomized, controlled, open-label, phase IIa clinical study.The study will observe the efficacy and safety of Deuteporfin photodynamic therapy in addition to stenting compared to stenting alone in patients with unresectable advanced Perihilar Cholangiocarcinoma.

NCT ID: NCT02953418 Terminated - Clinical trials for Esophageal Squamous Cell Neoplasia (ESCN)

RFA for Flat Type High-grade and Medium-grade Intraepithelial Squamous Neoplasia

REACH
Start date: April 20, 2017
Phase: N/A
Study type: Interventional

Multicenter, prospective cohort clinical trial in greater China

NCT ID: NCT02952586 Terminated - Clinical trials for Squamous Cell Carcinoma of the Head and Neck

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

Start date: November 28, 2016
Phase: Phase 3
Study type: Interventional

This is a phase 3 randomized, placebo controlled study to evaluate the safety and anti-tumor activity of Avelumab in combination with standard of care chemoradiation (SoC CRT) versus SoC CRT alone in front-line treatment of patients with locally advanced head and neck cancer.