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NCT ID: NCT06165991 Not yet recruiting - Clinical trials for Postoperative Analgesia

Efficacy and Safety of Liposomal Bupivacaine in Thoracic Paravertebral Nerve Block

Start date: June 1, 2024
Phase: Phase 4
Study type: Interventional

I. Research purpose 1.1 Main Objective: To investigate the efficacy and safety of bupivacaine liposome thoracic paravertebral nerve block combined with drainage tube analgesia for postoperative analgesia after thoracoscopic lobectomy 1.2 Secondary objective: To investigate the efficacy and safety of drainage tube analgesia after thoracoscopic lobectomy 1.3 Exploratory Objective: To investigate the noninferiority of bupivacaine liposomes in thoracic paravertebral nerve block with standard bupivacaine

NCT ID: NCT06165900 Recruiting - Breast Cancer Clinical Trials

Stereotactic Radiotherapy Combined With Adebrelimab and TCb (Nab-paclitaxel + Carboplatin) in Neoadjuvant Treatment of TNBC

Start date: September 26, 2023
Phase: Phase 2
Study type: Interventional

This study was an open-label, multicenter, randomized study. It is planned to include 136 patients with stage II-III triple negative breast cancer. Eligible subjects will be randomized to receive either the experimental arm: adebrelimab plus stereotactic radiotherapy followed by adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin) or the control arm: adebrelimab plus nab-paclitaxel + carboplatin.

NCT ID: NCT06165887 Not yet recruiting - Clinical trials for Moderate-to-severe Psoriasis

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance

Start date: February 2024
Phase:
Study type: Observational

Psoriasis is a common chronic and systemic immune-mediated disease, induced by a combination of genetic and environmental effects. The increasingly worrying question is the negative impact on patients' sleep, which has become an important comorbidity of psoriasis. To investigate the causal relationship between psoriasis and sleep status, a prospective cohort study will be conducted by separating moderate-to-severe psoriasis patients and healthy individuals into distinct cohorts in order to observe their sleep status.

NCT ID: NCT06165874 Recruiting - Clinical trials for Non-small Cell Lung Cancer

[68Ga]Ga-NOTA-RW102 PET Imaging in the Diagnosis of PD-L1-expressing Lung Cancer

Start date: March 12, 2023
Phase: N/A
Study type: Interventional

The aim of this study was to establish and optimize the imaging method of [68Ga]Ga-NOTA-RW102, as well as its physiological and pathological distribution characteristics, on the basis of which the diagnostic efficacy of the above imaging agent was evaluated in patients with non-small cell lung cancer

NCT ID: NCT06165822 Not yet recruiting - Clinical trials for Advanced Malignant Neoplasm

A Study to Evaluate Drug-Drug Interaction of TQB3909 Tablets

Start date: December 2023
Phase: Phase 1
Study type: Interventional

This is a single-center, open, single-dose, self-controlled phase I clinical trial to evaluate the effects of Itraconazole Capsules/Rifampicin Capsules on pharmacokinetics of TQB3909 tablets in vivo, and the safety of TQB3909 tablets and combined with Itraconazole Capsules/Rifampicin Capsules after single oral dose.

NCT ID: NCT06165809 Withdrawn - Clinical trials for Advanced Malignant Neoplasm

A Clinical Trial of TQB3015 Tablets in Patients With Advanced Malignant Cancer

Start date: December 2023
Phase: Phase 1
Study type: Interventional

This study is divided into two stages: dose escalation and dose extension, including a single dose and a multiple dose clinical study. This is a single-center, open, non randomized, single arm study to the safety and tolerability of TQB3015 tables in patients with advanced malignant cancer.

NCT ID: NCT06165757 Completed - Pain Clinical Trials

The Effects of Non Harmonic and White Noise on Human Pain Sensitivity: a Study of Healthy Volunteers

Start date: October 10, 2023
Phase: N/A
Study type: Interventional

Study the effects of 60dB and 80dB white noise, 50-70dB and 70-90dB non harmonic tones on the basic pain threshold of subjects, including the threshold and tolerance of electrical stimulation pain,the threshold and tolerance of cold pain stimulation, and the threshold and tolerance of tenderness stimulation.

NCT ID: NCT06165718 Recruiting - Clinical trials for Pulmonary Artery Sarcoma

Study for the Clinical Roadmap and Prognosis of Pulmonary Artery Sarcoma.

Start date: December 31, 2022
Phase:
Study type: Observational

This is an observational study in which patients with pulmonary artery sarcoma were followed up for at least 36 months and survival was investigated.

NCT ID: NCT06165549 Recruiting - Clinical trials for Internet Gaming Disorder

Light Therapy for Internet Gaming Disorder

Start date: December 16, 2023
Phase: N/A
Study type: Interventional

This project aims to investigate (1) the efficacy of light therapy on internet gaming disorder (IGD); (2) the underlying neural mechanisms of such efficacy

NCT ID: NCT06165471 Recruiting - Nursing Education Clinical Trials

The Effectiveness of a Mobile Application for Teaching Clinical Nursing Skill at a Higher Education Institution in Chenzhou, China

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

The general objective of this study is to validate a mobile application as a pedagogical tool compared to in-person nursing educational instruction for teaching clinical nursing skills and evaluate the effectiveness of clinical nursing skills for nursing students. The study design is a basic experimental study design, randomized control trial (RCT) design; the dependent variables measured in this study are skills, self-directed learning ability, online academic emotion, and satisfaction by using pre- and posttests; two groups are participating in this study; experimental and control group. The control group treatment is traditional face-to-face teaching, and the experimental group intervention is online and offline blended learning based on the Chaoxing app. The study process includes four steps: 1. To develop surgical nursing practical online courses using Chaoxing mobile app. 2. Perform the pre-test (basic sociological information, self-directed learning ability surveys ). 3. Nursing clinical practice skills education intervention. 4. Perform a posttest (assess practical skills, self-directed learning ability, online academic emotion, and satisfaction).