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NCT ID: NCT06419088 Recruiting - Education Clinical Trials

Effect of Preoperative Individualized Education on Anxiety and Recovery.

Start date: March 12, 2024
Phase: N/A
Study type: Interventional

Researchers aim to investigate whether individualized preoperative education for patients is beneficial in reducing perioperative anxiety, promoting postoperative recovery, and enhancing postoperative quality of life. The educational content will cover aspects such as the surgery procedure, anesthesia, postoperative pain and anxiety management, recovery time, and any potential required treatments. All participants will be administered a questionnaire before the surgery to evaluate their specific concerns and fears. The intervention group will receive preoperative education through audio-visual materials followed by targeted preoperative counseling, while the control group will receive routine preoperative education.

NCT ID: NCT06418828 Recruiting - Return to Work Clinical Trials

Patients With Type B Aortic Dissection Returning to Work After Discharge:a Cross-sectional Survey

Start date: January 1, 2024
Phase:
Study type: Observational

This study wants to understand the incidence of returning to work after discharge in patients with type B aortic dissection.

NCT ID: NCT06418698 Recruiting - Stroke Clinical Trials

The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy

CAIS-MT
Start date: March 28, 2024
Phase:
Study type: Observational [Patient Registry]

CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or medium vessel occlusion.

NCT ID: NCT06418581 Recruiting - Burnout Clinical Trials

Investigation on Burnout of Physicians

Start date: April 19, 2024
Phase:
Study type: Observational

This study proposes to analyze the burnout, emotional states, and sleep conditions of internal medicine doctors at the Second Affiliated Hospital of Zhejiang University School of Medicine through a questionnaire survey. The findings aim to provide reference for implementing measures to address burnout among medical staff, improve their physical and mental health, and enhance the quality of healthcare.

NCT ID: NCT06418568 Recruiting - Chloasma Clinical Trials

Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Melasma is a prevalent chronic facial pigmentation condition affecting Asian women of childbearing age, attributed to genetic predisposition, sunlight exposure, and hormonal changes. Treatment methods include phototherapy and medication, notably tranexamic acid, which inhibits melanin production. Ultra-pulsed shockwave therapy is a non-invasive approach that boosts skin cell vitality and collagen synthesis. Currently, there is a lack of comprehensive research on the effectiveness and safety of using ultra-pulsed shockwaves to deliver tranexamic acid for melasma treatment. This study will involve a non-randomized, self-half-face, pre-post controlled prospective clinical trial. This design aims to evaluate the depigmenting effects and safety profile of tranexamic acid delivered via ultra-pulsed shockwaves.

NCT ID: NCT06418555 Recruiting - Clinical trials for Transcatheter Aortic Valve Replacement Surgery

Construction and Application Research of Home Cardiac Rehabilitation Plan for Patients Undergoing Transcatheter Aortic Valve Replacement Based on Mobile Healthcare

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Cardiac rehabilitation is a long-term process, but patients have poor compliance with cardiac rehabilitation. The theory of behavior change rotation aims to comprehensively intervene from three aspects: ability, opportunity, and motivation, promoting individual behavior change by selecting the best intervention function and maximizing the use of available resources. To improve the compliance of TAVR patients with digital home cardiac rehabilitation, this study is based on the needs of TAVR patients and their caregivers for digital home cardiac rehabilitation. Based on the best evidence summary of TAVR patients' home cardiac rehabilitation, a home cardiac rehabilitation plan for TAVR patients is constructed using the theory of behavior change wheels. The Delphi method is used to revise the plan, develop a TAVR patient home cardiac rehabilitation management system, and conduct clinical application research on the plan to explore the intervention effect of TAVR patients' home cardiac rehabilitation based on real-time information intervention.

NCT ID: NCT06418490 Recruiting - Choledochal Cyst Clinical Trials

The Application of Digital Intelligent Diagnostic and Therapeutic Technology in Biliary Dilation Diagnosis

DIIBD
Start date: July 1, 2024
Phase:
Study type: Observational [Patient Registry]

This research discusses the clinical application value of augmented reality navigation technology combined with three-dimensional visualization technology in improving surgical safety and promoting the development of precision surgery. This technology can reduce intraoperative vascular and bile duct injuries, effectively avoid serious postoperative complications, and reduce residual cysts.

NCT ID: NCT06418477 Recruiting - Clinical trials for Monoclonal Gammopathy of Renal Significance

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Start date: May 28, 2024
Phase: Phase 2
Study type: Interventional

This is an open-label, multicenter, Phase 2 study in subjects with newly diagnosed monoclonal immunoglobulin deposition disease treated with daratumumab, bortezomib, cyclophosphamide, and dexamethasone.

NCT ID: NCT06417736 Recruiting - Clinical trials for Endometrial Hyperplasia

Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effect and adverse side effects of membrane-inhibiting formula plus oral progestins as fertility-preserving treatment in patients with early-stage endometrial cancer and endometrial hyperplasia research questions:When taken with oral progestins, does the drug membrane-inhibiting formula shorten the time required for complete endometrial remission? What medical problems do participants have when taking drug membrane-inhibiting formula plus oral progestins? Efficacy, side effects, recurrence, pregnancy, and time to obtain pregnancy in different molecular classifications of POLE-mutated, mismatch repair-deficient(MMRd), p53 wild type(p53wt), and p53-abnormal(p53abn). Participants will: Take drug membrane-inhibiting formula plus oral progestins every day Visit the clinic once every 3 months for checkups, tests, and hysteroscopy Keep a diary of examination results and pathology

NCT ID: NCT06417567 Recruiting - Clinical trials for General Anesthesia Gastrointestinal Cancer Surgery

The Safety and Effectiveness of NEPA in Preventing Postoperative Nausea and Vomiting After General Anesthesia Gastrointestinal Cancer Surgery: A Single-Center Retrospective Study

Start date: May 15, 2024
Phase:
Study type: Observational [Patient Registry]

The rapid progress of multiple antiemetic regimens ensures that patients can receive full dose chemotherapy, however, there are still a large number of unmet clinical needs in patient evaluation and treatment. Due to the fact that patients with liver, gallbladder, and pancreatic diseases undergoing surgery are still in the stage of nausea and vomiting, the actual incidence of delayed nausea and vomiting may be underestimated. The long-term effective control of nausea and vomiting by Nitopitan Palonosetron capsules may improve the quality of life of patients during and after treatment, and ultimately improve clinical outcomes