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NCT ID: NCT06252987 Recruiting - Stroke Clinical Trials

The Effects of tDCS Combined With rTMS on Post-stroke Cognitive Impairment

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

If there is a comparison group: Researchers will compare [insert groups] to see if [insert effects] The purpose of the clinical trial is to find a treatment for stroke patients with cognitive impairment, and the main questions it aims to answer are: - [Search for effective treatments of cognitive impairment after stroke] - [Explore brain network features with functional near-infrared spectroscopy] Participants will receive conventional treatment, tDCS treatment, or rTMS treatment, or tDCS-rTMS treatment. And then compare cognitive function and brain function.

NCT ID: NCT06252779 Recruiting - Clinical trials for Chronic Insomnia Disorder

Study on the Therapeutic Effect and Mechanism of Transcranial Plasma Stimulation in the Treatment of Chronic Insomnia

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This study is a single center study, led by Dr. Ma Qinying from the Department of Neurology at the First Hospital of Hebei Medical University. This study is an intervention study on plasma stimulation, involving patients with insomnia disorders to observe the effectiveness of plasma stimulation on insomnia disorders. Collect the Hamilton Anxiety Scale, Hamilton Depression Scale, Pittsburgh Sleep Quality Index Scale, Insomnia Severity Index Scale, and Somatization Symptom Self Rating Scale from patients before and after intervention. Transcranial magnetic stimulation synchronous electroencephalogram (TMS-EEG) and functional magnetic resonance imaging data. The research period is from July 2023 to July 2024, and a total of 40 patients are planned to be included in the study.

NCT ID: NCT06252298 Recruiting - Clinical trials for Relapsed or Refractory Hematologic Malignancies

A Clinical Study of SCTC21C in Participants With CD38+ Hematologic Malignancies

Start date: February 28, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of SCTC21C in patients with CD38+ hematologic malignancies

NCT ID: NCT06252025 Active, not recruiting - Clinical trials for Emotional Regulation

Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

A VR game "Memo-gration" was designed to assist elderly people in reminiscence therapy. The ultimate scene design was crafted in a vintage Chinese aesthetic reminiscent of the previous century.

NCT ID: NCT06251947 Recruiting - Ovarian Cancer Clinical Trials

Efbemalenograstim Alfa Injection for Ovarian or Cervical Cancer Receiving Chemotherapy Regimen

Start date: April 15, 2024
Phase: Phase 2
Study type: Interventional

The aim of this study was to observe the efficacy and safety of Efbemalenograstim Alfa in the prevention of absolute neutrophil count (ANC) reduction after chemotherapy in Ovarian and Cervical cancer patients at risk of platinum-containing chemotherapy with risk factors in febrile neutropenia (FN).

NCT ID: NCT06251882 Completed - Clinical trials for Meralgia Paresthetica

Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Meralgia paresthetica (MP) is one of the most common peripheral entrapment neuropathies of the lower limbs. It is characterized by paresthesia, pain, tingling, numbness, hypersensitivity, or other abnormal skin sensations on the anterolateral aspect of the thigh. The condition results from compression of the lateral femoral cutaneous nerve (LFCN) along its course, often occurring as the nerve exits the pelvis.The injection of 5% dextrose (D5W) under ultrasound guidance is a novel treatment method for peripheral nerve entrapment. However, there is limited evidence about the efficacy of this method for patients with MP. The investigators found D5W was more safe and effective than corticosteroids for patients with MP. Thus, this study aimed to evaluate the 6-month efficacy of ultrasound-guided injection of D5W for MP patients.

NCT ID: NCT06251674 Completed - Clinical trials for Carpal Tunnel Syndrome

Efficacy of Ultrasound-guided Transverse Carpal Ligament Release for Carpal Tunnel Syndrome

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is one of the most common peripheral nerve entrapment neuropathies, and it is characterized by pain, numbness, tingling, and weakness in the regions innervated by the median nerve (MN). CTS is believed to result from compression of the MN as it passes through the narrowed carpal tunnel with regard to gradual ischemia and fibrosis.Ultrasound-guided needle release of transverse carpal ligament(TCL) is an effective method to decompress the carpal.There are two main approaches to perform the release, short-axis or long-axis. However, there is no consensus about the optimal strategy.Thus, this study aimed to compare the efficacy of these two approaches for patients with mild-to-moderate CTS.

NCT ID: NCT06251492 Recruiting - Clinical trials for Prostate Cancer Metastatic

Radiation and Adebrelimab in Prostate Cancer With Imaging-measurable Disease (RAPID)

Start date: January 30, 2024
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy of 2 cycles of combinatory adebrelimab and stereotactic radiotherapy, followed by monotherapy adebrelimab in patients with metastatic castration-resistant prostate cancer. Dr. Yao Zhu from Fudan University Shanghai Cancer Center is the co-leading PI of this study.

NCT ID: NCT06251414 Completed - Clinical trials for Chronic Ankle Instability,CA

Study on the Effect of Exercise Intervention Combined With Physical Therapy on Chronic Ankle Instability Symptoms

CAI
Start date: November 20, 2023
Phase: N/A
Study type: Interventional

Purpose; Through experimental observation of exercise intervention (blood flow restriction training combined with low load ankle muscle strength training and balance training) combined with instrument tool therapy (Instrument Soft Tissue Release Technique, IASTM), the intervention effect on ankle function, strength, and joint range of motion of sports dance athletes with ankle instability was observed. Method; 45 subjects with unstable, restricted or uncomfortable ankle joints were selected as observation subjects and randomly divided into ankle blood flow restriction training combined with IASTM group (n=15), ankle blood flow restriction training alone (n=15), and traditional ankle strength training (n=15). The intervention lasted for 6 weeks, once a week. Cumberland ankle instability assessment, FAAM ankle function assessment score, and ankle range of motion measurement were performed at three time points before intervention, after the first intervention, and after 6 weeks of intervention for three groups. The ankle strength test was only compared and analyzed at two time points before and after intervention.

NCT ID: NCT06251388 Recruiting - Cervical Cancer Clinical Trials

A Study of Concurrent Chemoradiotherapy Followed by Cadonilimab(AK104) for Newly Diagnosed Local Advanced Cervical Cancer

Start date: February 20, 2024
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of concurrent chemoradiotherapy(CCRT)followed by cadonilimab(AK104) in high risk local advanced cervical cancer. Participants received CCRT,efficacy evaluation of CCRT was no disease progression who maintained with AK104(10.0 mg/kg,Q3W)until drug exposure over 1 years or disease progression or intolerable toxicity.