Clinical Trials Logo

Filter by:
NCT ID: NCT06265493 Completed - Geriatrics Clinical Trials

Postoperative Infectious Complications Calculator for Elderly Patients

Start date: June 1, 2021
Phase:
Study type: Observational

The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients. Our scoring system can aid in the early detection of potential risks for postoperative infections. Higher-score patients were more likely to experience postoperative infections.

NCT ID: NCT06265428 Recruiting - Clinical trials for HER2-positive Breast Cancer

A Study to Compare DB-1303/BNT323 Versus T-DM1 in Breast Cancer

Start date: January 29, 2024
Phase: Phase 3
Study type: Interventional

This study is designed to compare efficacy and safety of DB-1303/BNT323 versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer patients previously treated with trastuzumab and taxane.

NCT ID: NCT06265350 Recruiting - Clinical trials for Hepatocellular Carcinoma

Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

This study intends to evaluate the efficacy and safety of cryoablation combined with Cardonilizumab and Bevacizumab in hepatocellular carcinoma with pulmonary metastases.

NCT ID: NCT06265311 Recruiting - Ultrasonography Clinical Trials

IDUS in CBD Stone Recurrence High Risk Patients

Start date: November 2, 2021
Phase: N/A
Study type: Interventional

This study is designed to observed CBD stones cases with high recurrence risks applying IDUS or not during ERCP. Patients with CBD stone high recurrence risks were enrolled in this study, and prospectively randomized into IUDS group and control group during lithotomy. Operation time, radiation time, hospitalization cost, retain of nasobiliary tube, deployment of stent were recorded. Symptoms and conditions after ERCP were also followed up including blood amylase, routine blood test, abdominal pain, post-ERCP pancreatitis, resection of gallbladder, recurrence of CBD stone and onset of cholangitis.

NCT ID: NCT06265155 Recruiting - Clinical trials for Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion

Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion

Start date: February 1, 2024
Phase:
Study type: Observational

Acute ischemic stroke has a high incidence, ischemic stroke caused by large vessel occlusion is serious and has a poor prognosis, and its triggers in the short term before onset are not clear. The aim of this study was to evaluate the short-term risk of acute ischemic stroke caused by multiple triggers. In this trial, through a case-crossover study design, patients were asked about the exposure to each trigger in the previous year and the exposure during the preictal risk period (the exposure observed during the risk period) for each potential trigger of acute ischemic stroke caused by large vessel occlusion. To evaluate the relative risk of ischemic stroke resulting from exposure to triggers, comparing exposure during the dangerous period with the usual frequency of exposure. Relative risks and corresponding 95% CIs were estimated for past-year exposure and past-year mean exposure (assessed as chronic risk factors) and time to last exposure (assessed as triggers). Scientifically evaluate exposure to a range of potential triggers, including infection, mood, smoking, alcohol consumption, diarrhea and vomiting, extreme temperature changes, and several factors that increase blood pressure and their risk of developing acute ischemic stroke.

NCT ID: NCT06265051 Recruiting - Clinical trials for Acute Ischemic Stroke

Tirofiban After Successful MT Recanalization in AIS

ATTRACTION
Start date: April 9, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Acute ischemic stroke with large vessel occlusion is a frequently occurring life-threatening condition. Although endovascular treatment can effectively open occluded vessels, the successful reperfusion rate exceeds 80%, but the rate of good prognosis is less than 50%. The current clinical focus is on how to improve futile recanalization. Tirofiban is widely used in the treatment of stroke, as it can effectively prevent vascular reocclusion and improve microcirculation perfusion. It has the potential to improve futile recanalization, but there is a lack of high-level evidence-based medical support. This multicenter, prospective, double-blind, randomized controlled trial was conducted to assess the effectiveness and safety of sequential tirofiban therapy following successful mechanical thrombectomy within 24 hours of onset.

NCT ID: NCT06264804 Recruiting - Refractive Surgery Clinical Trials

Risk Factors for Progressive Suction Loss in Corneal Refractive Surgery

Start date: February 16, 2024
Phase:
Study type: Observational

The goal of this Prospective observational studiesis to Characteristics of progressive suction loss.

NCT ID: NCT06263959 Recruiting - Chronic Hepatitis B Clinical Trials

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Start date: December 29, 2023
Phase: Phase 2
Study type: Interventional

A randomized, double-blind, placebo-controlled Phase IIa clinical study to evaluate the safety and efficacy of GST-HG131 tablets in patients with chronic hepatitis B

NCT ID: NCT06263465 Recruiting - Bacterial Vaginosis Clinical Trials

Precision Vaginal Microbiome Transplantation in Women With Bacterial Vaginosis

Start date: March 18, 2024
Phase: N/A
Study type: Interventional

The aim of this study was to explore the efficacy and safety of a new vaginal microbiome transplantation technique, using Lactobacillus cispatus from healthy donors as a treatment of bacterial vaginosis.

NCT ID: NCT06263348 Recruiting - Type2diabetes Clinical Trials

A Post-Marketing Safety Study of Dorzagliatin in Patients With Type 2 Diabetes

Start date: December 20, 2023
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to evaluate the long-term safety of Dorzagliatin in a larger population of type 2 diabetes mellitus patients by collecting the post-marketing clinical safety data of Dorzagliatin.