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NCT ID: NCT06190301 Recruiting - Clinical trials for Primary Ocular Adnexal MALT Lymphoma

RCT on Intralesional Rituximab Injection Versus ISRT in Ocular Adnexal MALT Lymphoma

Start date: January 11, 2024
Phase: N/A
Study type: Interventional

This project proposes to establish a prospective, multicenter, randomized, controlled clinical study to compare the safety and efficacy of Intralesional Rituximab Injection versus Involved Site Radiation Therapy for the treatment of primary ocular adnexal MALT lymphoma. The aim is to provide high-level clinical evidence for the treatment of ocular adnexal MALT lymphoma and to offer patients treatment options that have fewer complications and comparable therapeutic effects.

NCT ID: NCT06190145 Recruiting - Clinical trials for Immune Thrombocytopenia

Teriflunomide for Steroid-resistant/Relapse Immune Thrombocytopenia

Start date: December 5, 2023
Phase: Phase 2
Study type: Interventional

Single-arm, open-label, single-center study to evaluate the efficacy and safety of teriflunomide for the treatment of adults with steroid-resistant/relapse immune thrombocytopenia (ITP).

NCT ID: NCT06190119 Recruiting - Glaucoma Clinical Trials

Comparison of Aqueous Humor Adipokines in Glaucoma Patients and Healthy Controls

Start date: October 8, 2023
Phase:
Study type: Observational

The purpose of this study is to observe whether there are differences in adipokines in the aqueous humor between patients with primary open-angle glaucoma (POAG) and healthy controls

NCT ID: NCT06190067 Recruiting - Clinical trials for Refractory Classic Hodgkin Lymphoma

Azacitidine Plus PD-1 Therapy for R/R Hodgkin Lymphoma

Start date: October 30, 2023
Phase: Phase 2
Study type: Interventional

The goal of this phase 2 trial is to test the safety and efficacy of azacitidine when given together with PD-1 therapy in treating patients with relapsed/refractory classic Hodgkin lymphoma.

NCT ID: NCT06189950 Recruiting - Clinical trials for Intracranial Aneurysm

Registration Trial of the Intracranial Visualized Stent for the Wide-necked Intracranial Aneurysms:REBRIDGE

Start date: October 30, 2023
Phase: N/A
Study type: Interventional

This trial was designed as a prospective, multicentre, open, non-inferiority, randomised controlled clinical trial, with the control devices being MicroVention's LVIS Intraluminal Support Device and LVIS Jr. Intraluminal Support Device. Approximately 200 subjects with intracranial aneurysms would be enrolled for stent-assisted coiling embolisation according to the inclusion and exclusion criteria specified in this trial protocol. Subjects were evaluated by mRS preoperatively, at the time of device implantation, at the time of discharge from the hospital, at 1 month (±7 days) postoperatively, at 6 months (±30 days) postoperatively, and at 12 months (±60 days) postoperatively; subjects would underwent DSA imaging at surgery and at 6 months (±30 days) postoperatively, and MRA or DSA imaging at 12 months (±60 days) postoperatively. Unplanned follow-up of the subjects would performed when necessary, and data would be recorded to evaluate the safety and efficacy of intracranial artery stent for stent-assisted coiling embolisation for the treatment of intracranial aneurysms.

NCT ID: NCT06189391 Recruiting - Clinical trials for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN201

Start date: March 4, 2021
Phase: Phase 1
Study type: Interventional

This study aims to provide a basis for further clinical development of CN201.

NCT ID: NCT06189365 Recruiting - Clinical trials for Non-Valvular Atrial Fibrillation

Amplatzer Amulet China Post Market Study (PMS)

Start date: January 30, 2024
Phase:
Study type: Observational

The purpose of this study is to prospectively evaluate the safety and effectiveness of the Amplatzer Amulet LAA occluder in a Chinese patient population indicated for use of this device.

NCT ID: NCT06189183 Recruiting - Thymus Neoplasms Clinical Trials

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

Start date: November 11, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficiency and toxicity of adjuvant hypofractionation radiotherapy for thymic epithelial tumours after complete resection.

NCT ID: NCT06188650 Recruiting - Clinical trials for Non-Small Cell Lung Cancer

The Efficacy and Safety of Drug Loaded Microsphere Bronchial Artery Chemoembolization (DEB-BACE) Combined With Anlotinib and Adebelimumab in the Third Line Treatment of Advanced NSCLC: a Prospective, Single Arm, Single Center, Exploratory Clinical Study

Start date: December 9, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about Drug loaded microspheres for bronchial artery chemoembolization (DEB-BACE) combined with anlotinib and adebelimumab in patients with advanced NSCLC after second-line treatment. The main question it aims to answer is: The efficacy and safety of Drug Loading Beads Bronchial Arterial Chemoembolization (DEB-BACE) combined with Anlotinib and Adebelimumab in the third line treatment of advanced NSCLC. Participants will receive DEB-BACE treatment, rest for 1 week and then undergo 1 cycle of treatment with combination of Anlotinib and Adebelimumab. With a maximum of 4 DEB-BACE treatments depending on the therapeutic effect, followed by continued treatment with Anlotinib and Adebelimumab.

NCT ID: NCT06188624 Recruiting - Advanced Cancer Clinical Trials

Clinical Trial of TQB2922 for Injection in Patients With Advanced Cancers

Start date: February 1, 2024
Phase: Phase 1
Study type: Interventional

This is a Phase I study to evaluate the safety, tolerability, and efficacy of TQB2922 for injection in subjects with advanced cancers