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NCT ID: NCT05512598 Completed - Clinical trials for Generalized Pustular Psoriasis

HB0034 in Patients With Generalized Pustular Psoriasis (GPP)

Start date: November 6, 2022
Phase: Phase 1
Study type: Interventional

This is a study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of HB0034 in adult patients with generalized pustular psoriasis (GPP ).

NCT ID: NCT05512494 Completed - Seasonal Influenza Clinical Trials

Lot-to-lot Consistency of Quadrivalent Influenza Vaccine (Split Virion), Inactivated

Start date: November 27, 2022
Phase: Phase 4
Study type: Interventional

This study is a randomized, double-blind phase Ⅳ clinical trial of quadrivalent influenza vaccine (Split Virion), inactivated manufactured by Sinovac Biotech Co., Ltd.The purpose of this study is to evaluate the lot-to-lot consistency, immunogenicity and safety of quadrivalent influenza vaccine (Split Virion), inactivated in health subjects aged 9-59 years old.

NCT ID: NCT05512442 Completed - Tooth Loss Clinical Trials

Comparison of the Centric Relation Recorded by Two Methods Using Cone Beam Computed Tomography

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate and compare the variation in mandibular relation recorded by the gothic arch methods and the K7 method using cone beam computed tomography (CBCT)

NCT ID: NCT05511870 Completed - Clinical trials for Healthy Chinese Subjects

A Study of Etripamil in Healthy Subjects

Start date: March 7, 2023
Phase: Phase 1
Study type: Interventional

The objectives of the study are as below: Primary: ·To evaluate the pharmacokinetics (PK) of Etripamil in healthy adult Chinese subjects Secondary: - To evaluate the pharmacodynamics (PD) of Etripamil in healthy adult Chinese subjects - To evaluate the safety and tolerability of Etripamil in healthy adult Chinese subjects Exploratory: ·To evaluate the PK exposure-PD response relationship of etripamil in healthy adult Chinese subjects

NCT ID: NCT05511649 Completed - Clinical trials for Acute Myocardial Infarction

New-Onset Atrial Fibrillation Complicating Acute Myocardial Infarction in China

NOAFCAMI-China
Start date: March 1, 2023
Phase:
Study type: Observational

To investigate the prognostic impacts of the atrial fibrillation burden (AFb) in acute myocardial infarction (AMI) patients who developed paroxysmal new-onset atrial fibrillation (NOAF) during the index AMI hospitalization.

NCT ID: NCT05511506 Completed - Cataract Clinical Trials

Cytokines in Femtosecond Laser-assisted Cataract Surgery

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The investigators performed the current study to compare: 1) the pain scores by Visual Analogue Scale; 2) the cytokines concentrations in aqueous humor by human cytokine antibody array; 3) the prostaglandin E2 (PGE2) concentrations by enzyme linked immunosorbent assay (ELISA); 4) the pupil behaviors by Image J between first-eye and second-eye in bilateral cataract patients undergoing sequential femtosecond laser-assisted cataract surgery (FLACS). To our knowledge, this is the first intraindividual study investigating contralateral effect in FLACS. The findings from the current study may broaden our understanding on the mechanism of sympathetic reaction, help to improve clinical performances, and provide strong clinical guidance for cataract surgeons.

NCT ID: NCT05510414 Completed - Burnout Clinical Trials

Evaluation of a Psychological Capital Intervention to Alleviate Burnout and Regulate Immunity Among Oncology Nurses

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Burnout appears to be highly prevalent among oncology nurses, which was a problem not only for the nurses themselves but for the patients for whom they provide care. How to mitigate and prevent burnout and improve nursing performance outcomes is an urgent problem for nursing manager. In a sample of 99 oncology nurses, immunological characteristics were compared to burnout scores. In a randomized trial, 90 oncology nurses suffering burnout were randomized to receive psychological capital intervention or routine psychological care. Participants were assessed before and after treatment using measures of burnout, psychological capital and immunological characteristics.

NCT ID: NCT05510037 Completed - Breast Cancer Clinical Trials

Incidence and Prognostic Significance of HER-2 Status Discordance Between Primary Breast Cancer and Paired Recurrent/Metastatic Lesions

Start date: January 1, 2021
Phase:
Study type: Observational

About a half of HER2-negative breast cancer show HER2-low expression that can be targeted by new antibody-drug conjugates. The main aim of this study is to describe the evolution of HER2 expression from primary BC to relapse by including HER2-low category in both primary and recurrent BC samples. Patients with matched primary and relapse BC samples were included. 1299 patients were included.

NCT ID: NCT05509634 Completed - Clinical trials for Prevention of Nausea and Vomiting Caused by Highly Emetogenic Chemotherapy

Clinical Study of HR20013 for Injection in Patients With Malignant Solid Tumors

Start date: September 21, 2022
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of HR20013 for injection for prevention of chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy.

NCT ID: NCT05509361 Completed - Plaque Psoriasis Clinical Trials

Open Label Study to Evaluate the Safety and Efficacy of AK101 Injection Subcutaneously in Subjects With Psoriasis

Start date: April 8, 2022
Phase: Phase 3
Study type: Interventional

This is an open-label Phase III clinical study to evaluate the long-term safety and efficacy of AK101 injection in subjects with moderate-to-severe plaque psoriasis.