Clinical Trials Logo

Filter by:
NCT ID: NCT05643651 Not yet recruiting - Kawasaki Disease Clinical Trials

Rivaroxaban for Children With Giant Coronary Artery Aneurysms After Kawasaki Disease

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

Based on population pharmacokinetic model-based simulation, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after acute Kawasaki disease was proposed. This exploratory trial aims to evaluate the feasibility, safety and effectiveness of rivaroxaban compared to warfarin for thromboprophylaxis in children with giant coronary artery aneurysms after Kawasaki disease

NCT ID: NCT05643417 Not yet recruiting - Clinical trials for Metastatic Liver Cancer

Camrelizumab Combined With Bevacizumab and HAIC in Patients With Metastatic Liver Cancer Who Failed Standard Therapy

Start date: December 2022
Phase: Phase 1
Study type: Interventional

This is a single center, multi-cohort, phase I basket trial to evaluate the safety and efficacy of camrelizumab in combination with bevacizumab and HAIC for metastatic liver cancer after standard treatment failure

NCT ID: NCT05641610 Not yet recruiting - Hemophilia B Clinical Trials

A Study to Evaluate the Safety and Efficacy of ZS801 in Adult Hemophilia B Patients

Start date: March 2023
Phase: Phase 1/Phase 2
Study type: Interventional

A non-randomized, open-label, dose-escalation, phase I/II study to evaluate the safety, tolerability, kinetics and efficacy of a single intravenous infusion of ZS801 in hemophilia B subjects with endogenous FIX ≤2%.

NCT ID: NCT05641506 Not yet recruiting - Ovarian Cancer Clinical Trials

A Chinese Patent Medicine Yangzhengxiaoji Capsule to Improve the Nausea of Niraparib in the Maintenance Treatment in Ovarian Cancer

Start date: December 2022
Phase: Phase 2
Study type: Interventional

This study is an open-label, single-Arm, phase II clinical trial of a Chinese Patent Medicine Yangzheng Xiaoji Capsule to improve the adverse reaction nausea of Niraparib in the first-line maintenance treatment in advanced epithelial ovarian cancer, fallopian tube cancer, and primary peritoneal cancer.

NCT ID: NCT05640713 Not yet recruiting - Clinical trials for Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited

Assessment of Safety and Efficacy of ThisCART19A in Adult Patients With B Cell Malignancies After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy

Start date: December 1, 2022
Phase: Phase 1
Study type: Interventional

This is a a phase 1, open label study to assess the safety and efficacy of ThisCART19 (Allogeneic CAR-T targeting CD19) in adult patients with B cell malignancies after failure of autologous chimeric antigen receptor T- cell(CAR-T) therapy in china.

NCT ID: NCT05636657 Not yet recruiting - Crohn Disease Clinical Trials

Comparative Study of Intestinal Color Ultrasound and Capsule Endoscopy in Monitoring Crohn's Disease

Start date: November 30, 2022
Phase:
Study type: Observational

The disease activity index under intestinal color ultrasound was evaluated by SUS-CD, and the disease activity index under capsule endoscopy was evaluated by CECDAI. All subjects underwent intestinal color ultrasound and capsule endoscopy at baseline and at the third month of treatment. To compare the correlation between SUS-CD and CECDAI before and after treatment, and to compare the role of intestinal color ultrasound and capsule endoscopy in monitoring Crohn's disease in small intestine.

NCT ID: NCT05636163 Not yet recruiting - Hemophilia A Clinical Trials

Neutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratio in Predicting the Incidence of Nausea and Vomiting

Start date: December 15, 2022
Phase:
Study type: Observational

By comparing the incidence of PONV, the dosage of postoperative antiemetic drugs, the postoperative VAS score and the utilization rate of PCIA of hemophilia A patients in the NLR≥2 and NLR<2 groups, investigators could find out the high value in the diagnosis of hemophilia A, which is helpful to guide the clinical diagnosis and treatment of hemophilia A.

NCT ID: NCT05634590 Not yet recruiting - Clinical trials for Metastatic Colorectal Cancer

The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer

Start date: December 2022
Phase: Phase 2
Study type: Interventional

RAS mutations are found in nearly half of colorectal cancer patients. However, there is no targeted driver gene drugs have been approved for RAS-mutated patients. For RAS mutant metastatic colorectal cancer, the commonly used treatment regimen is bevacizumab combined with chemotherapy.

NCT ID: NCT05634473 Not yet recruiting - Asthma Clinical Trials

A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test

Start date: December 2022
Phase: N/A
Study type: Interventional

A multicenter, open-label study to evaluate the sensitivity and specificity of inhaled methacholine in bronchial provocation test

NCT ID: NCT05633199 Not yet recruiting - Clinical trials for Cytoreductive Surgery

Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancer

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

This novel study was specifically designed for platinum-resistant recurrent ovarian cancers with PFI<6 months and aimed to compare prognosis of patients who received cytoreductive surgery followed by chemotherapy versus chemotherapy alone.