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NCT ID: NCT05569668 Completed - Esophagus Cancer Clinical Trials

Neoadjuvant Chemotherapy Compared With Surgery for Esophageal Carcinoma

Start date: January 1, 2021
Phase:
Study type: Observational

Most ESCC received NAC in China without supportive evidence from local RCTs. The negative conclusion about NAC originated from Western countries in the 1990s. Whether two-field extensive mediastinal lymphadenectomy and paclitaxel/platinum-based chemotherapy results in better survival should be determined. As the highest ESCC incidence area worldwid, we tried to analyze this top with big data by using a single-center case-control retrospective PMS study. Paclitaxel- and platinum-based NAC combined with two-field of the extensive mediastinal lymphadenectomy might provide better survival benefits than primary esophagectomy for stage II/III SCC.

NCT ID: NCT05569343 Completed - Clinical trials for Pancreatic Neoplasm of Uncertain Behavior Head

Risk Factors for Achieving TO After LDPPHR-t

Start date: May 8, 2020
Phase:
Study type: Observational

This is a single, retrospective, observational study to investigate the risk factors for achieving textbook outcome after laparoscopic duodenum-preserving total pancreatic head resection.

NCT ID: NCT05568992 Completed - Advanced Adenoma Clinical Trials

Prospective, Randomized Controlled Study to Evaluate the Effect of Artificial Intelligence Assisted Optical Diagnosis of Advanced Adenomas

Start date: October 6, 2022
Phase: N/A
Study type: Interventional

This study is a clinical validation of our developed a computer-aided optical dignosis of advanced adenoma using non-magnified NBI image. This study is a randomized clinical trial comparing endoscopists' optical recognition of advanced adenoma for sending to histological examination with our computer-aided system. The hypothesis of the study is that the developed computer-aided system increases the percent of sending actual advanced adenoma Intelligence Assisted Optical Diagnosis of Advanced Adenomas

NCT ID: NCT05567523 Completed - Hip Fractures Clinical Trials

Safety Study of Dexmedetomidine in Elderly Under General Anesthesia

Start date: June 1, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to find out appropriate dose range of dexmedetomidine to provide the elderly patients satisfactory sedation and analgesia with stable hemodynamics during perioperative period of hip replacement under general anesthesia.

NCT ID: NCT05567094 Completed - Clinical trials for Pancreaticoduodenectomy

The Effect of Perioperative DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy

PANDEX
Start date: October 8, 2022
Phase: Phase 4
Study type: Interventional

The primary objective of this clinical trial is evaluate the effect of dexamethasone on postoperative complications after pancreaticoduodenectomy.

NCT ID: NCT05565066 Completed - Clinical trials for Neuroendocrine Tumors

A Real-world Comparison of FNB and FNA in IHC-required Lesions.

Start date: December 1, 2014
Phase:
Study type: Observational

Endoscopic ultrasound (EUS)-guided fine needles with side fenestrations are used to collect aspirates for cytology analysis and biopsy samples for histologic analysis. The investigators conducted a large, multicenter study to compare the accuracy of diagnosis via specimens collected with fine-needle biopsy (FNB) versus fine-needle aspiration (FNA) for patients with lesions requiring immunohistochemistry (IHC) pathological diagnosis.

NCT ID: NCT05564286 Completed - Cervical Cancer Clinical Trials

Triple Antiemetic Regimen for Chemoradiotherapy in Cervical Cancer or Nasopharyngeal Cancer

Start date: July 1, 2021
Phase: Phase 3
Study type: Interventional

The study is to evaluate the antiemetic effect of adding fosaprepitant to biplet regimen of tropisetron and dexamethasone for patients with cervical cancer or nasopharyngeal cancer treated with radiotherapy and concomitant weekly cisplatin chemotherapy in a south Chinese cohort.

NCT ID: NCT05563545 Completed - Clinical trials for Acute Lymphoblastic Leukemia

Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia

Start date: July 21, 2022
Phase: Phase 1
Study type: Interventional

This study is a single arm clinical study to observe the safety ,dose tolerance and pharmacokinetic characteristics of CAR NK-CD19 in patients with recurrent or refractory CD19 positive acute lymphoblastic leukemia, and preliminarily evaluate the effectiveness, the immunogenicity of the product and the correlation between the changes of cytokines after infusion and CRS , ICANS.

NCT ID: NCT05563441 Completed - Colorectal Cancer Clinical Trials

Laparoscopic Colorectal Resection in Elderly

Start date: January 20, 2015
Phase:
Study type: Observational

This is a nested cohort study of OAMBP-01. Patients over 70 years old were enrolled into the data-analysis. The purpose of this study was to examine the feasibility and safety of laparoscopic colorectal resection in elderly patients from a single center, and to explore if there are advantages in laparoscopic surgery.

NCT ID: NCT05563246 Completed - Clinical trials for Lipoprotein Disorder

A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

KRAKEN
Start date: November 24, 2022
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to evaluate the efficacy and safety of LY3473329 in adult participants with elevated Lp(a) at high risk for cardiovascular events.