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NCT ID: NCT02752737 Active, not recruiting - Atrial Fibrillation Clinical Trials

Cryo Global Registry

Start date: May 2016
Phase:
Study type: Observational [Patient Registry]

Cryo Global Registry a prospective, global, multi-center, observational Post-Market Registry

NCT ID: NCT02752074 Completed - Melanoma Clinical Trials

A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)

Start date: June 21, 2016
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy, safety, and tolerability when combining pembrolizumab with epacadostat or placebo in participants with unresectable or metastatic melanoma

NCT ID: NCT02751970 Active, not recruiting - Dental Caries Clinical Trials

Clinical Trial of the Effect of Different Categories of Adhesive System

Start date: April 2014
Phase: Phase 2
Study type: Interventional

This study aims to evaluate the clinical effectiveness of contemporary resin-based adhesive systems by retention rate of resin restorations placed in non carious cervical lesions with four different adhesive strategies: 3 and 2 steps etch-and-rinse adhesive system, 2 and 1 step self-etch adhesive systems.

NCT ID: NCT02735655 Recruiting - Clinical trials for Gastrointestinal Endoscopy Training

Global State of Digestive Endoscopy Training Survey

Start date: April 2016
Phase: N/A
Study type: Observational

This is a 10 minutes web based survey aims at exploring the current, global state of digestive endoscopy training among physicians to identify what are the unmet needs and how to improve it.

NCT ID: NCT02735044 Completed - Clinical trials for Type 1 Diabetes Mellitus

Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus

EDITION JUNIOR
Start date: April 14, 2016
Phase: Phase 3
Study type: Interventional

Primary Objective: To compare the efficacy of a new formulation of insulin glargine (HOE901-U300) to Lantus in terms of change of HbA1c from baseline to endpoint (month 6) in children and adolescents with type 1 diabetes mellitus. . Secondary Objectives: To compare HOE901-U300 and Lantus in terms of: - Percentage of participants reaching target HbA1c and fasting plasma glucose (FPG). - To assess the safety of HOE901-U300 including analysis of events of hypoglycemia, events of hyperglycemia with ketosis, and development of anti-insulin-antibodies.

NCT ID: NCT02732418 Completed - Contraception Clinical Trials

Lower Dose Depo Provera® Contraceptive Injection

Start date: December 2, 2016
Phase: Phase 1
Study type: Interventional

This is a randomized, partially-blinded, multi-center, parallel-group study to evaluate and compare the PD and PK of MPA after a single SC injection of either 45 mg/0.3 mL, 75 mg/0.5 mL or 105 mg/0.7 mL of Depo-Provera CI, and one cycle of Depo-subQ 104 use when injected in the abdomen, in women of reproductive age with confirmed ovulatory baseline cycle

NCT ID: NCT02727660 Completed - Clinical trials for Chronic Obstructive Pulmonary Disorder

A Study to Assess the Efficacy and Safety of PT009 Compared to PT005 on COPD Exacerbations Over a 52-Week Period in Subjects With Moderate to Very Severe COPD (Sophos)

Start date: April 29, 2016
Phase: Phase 3
Study type: Interventional

This is a Phase III randomized, double-blind, parallel group, multi-center, 52-week COPD exacerbation and lung function study with PT009 320/9.6 μg, PT009 160/9.6 μg and PT005 9.6 μg, all administered BID.

NCT ID: NCT02724254 Completed - Condyloma Clinical Trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients

Start date: January 2016
Phase: Phase 2
Study type: Interventional

This is a double-blind placebo controlled, randomized, phase 2 study to assess the safety, tolerability, pharmacokinetics and efficacy of twice daily topical applications of AP611074 5% Gel for up to 16 weeks in condyloma patients

NCT ID: NCT02723136 Not yet recruiting - Education, Medical Clinical Trials

Implementation of a Smartphone Application in Medical Education: A Randomised Trial

iSTART
Start date: April 2016
Phase: N/A
Study type: Interventional

This study addresses the effectiveness of a smartphone application to improve academic performance among medical students. Participants will be randomised to receive an application developed by a team of physicians and engineers, designed to review key concepts in internal medicine and its subspecialties. The primary outcome will be the number of correct answers in a multiple choice test 4 weeks after randomisation.

NCT ID: NCT02707016 Recruiting - Delirium Clinical Trials

Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children

Start date: December 2015
Phase: N/A
Study type: Interventional

The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of anesthesia.