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NCT ID: NCT00142974 Terminated - Clinical trials for Diabetic Gastropathy

Assessment of the Effect of Tegaserod (2 mg Tid and 6 mg Tid) on Dyspeptic Symptoms in Diabetic Patients With Symptoms of Diabetic Gastropathy

Start date: May 2004
Phase: Phase 2
Study type: Interventional

This study is being done to evaluate the safety, tolerability and satisfactory relief of tegaserod against dyspeptic symptoms in diabetic patients with symptoms of diabetic gastropathy.

NCT ID: NCT00141973 Completed - Sepsis Clinical Trials

Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids

Start date: November 2004
Phase: N/A
Study type: Observational

A systemic treatment with corticosteroids has been advocated for various bacterial infectious diseases. Since the production of CRP is down-regulated by corticosteroids, a smaller increase or a more rapid decrease of this acute phase protein will: 1. suggest attenuated systemic inflammation, but 2. does not necessarily reflect adequate therapy of the infection. For several reasons (good diagnostic tool for sepsis, induction not decreased by immunosuppressive therapy), procalcitonin could be a better marker for activity of sepsis in patients under corticosteroids. As this issue has not yet been examined the investigators will prospectively study the time-course of PTC and CRP in a well-defined septic patient group, that in adjunction to antibiotic therapy also received systemic corticosteroid treatment and compare it to a similar group without corticosteroid treatment.

NCT ID: NCT00141427 Completed - Seizures Clinical Trials

Pregabalin In Partial Seizures: An Open-Label, International, Multicenter Add-On Therapy Trial.

Start date: November 2004
Phase: Phase 4
Study type: Interventional

To assess the clinical improvement (change in seizure frequency), safety and tolerability of patients with partial seizures following adjunctive therapy of pregabalin BID in addition to existing standard AEDs.

NCT ID: NCT00141245 Completed - Clinical trials for Seizure Disorder, Partial

To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

Start date: October 1998
Phase: Phase 3
Study type: Interventional

To evaluate long-term safety and efficacy of pregabalin in patients with partial seizures.

NCT ID: NCT00141193 Completed - Colorectal Adenoma Clinical Trials

Prevention of Colorectal Sporadic Adenomatous Polyps (PRESAP)

PRESAP
Start date: February 2001
Phase: Phase 3
Study type: Interventional

This study is a prospective, randomized, double-blind, placebo-controlled, multi-center trial to compare the efficacy and safety of celecoxib 400mg QD versus placebo in reducing the occurrence of new colorectal adenomas post-polypectomy at Month 13 (Year 1) and Month 37 (Year 3) of study drug administration.

NCT ID: NCT00140660 Terminated - Clinical trials for Diffuse Large Cell Lymphoma

ACVBP Versus ACVBP Plus Rituximab in Low Risk Localized Diffuse Large B-cell Lymphoma

Start date: December 2003
Phase: Phase 3
Study type: Interventional

This study is a multicentric randomized trial evaluating the efficacy of the combination R-ACVBP in patients 18 to 65 years with low risk localized diffuse large B-cell lymphoma.

NCT ID: NCT00140543 Completed - Clinical trials for Diabetes Mellitus, Type 1

European Trial of Immunosuppression in SPK Tx

Start date: February 2002
Phase: Phase 3
Study type: Interventional

1. To determine and compare the efficacy of Tacrolimus/Rapa versus Tacrolimus/MMF-based immunosuppression (in conjunction with initial short-term steroids and polyclonal antibody administration) in Type 1-diabetic patients undergoing simultaneous pancreas/kidney allograft transplantation. 2. To evaluate the safety of Tacrolimus/Rapa versus Tacrolimus/MMF in terms of drug-related complications and overimmunosuppression-associated complications, particularly under monitoring of the pharmacokinetic profile of all drugs administered.

NCT ID: NCT00139984 Completed - Hypertension Clinical Trials

Ambulatory Blood Pressure Monitoring for Antihypertensive Treatment Guidance

Start date: October 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether in patients with arterial hypertension, treatment guidance using 24-hour blood pressure measurement results in better blood pressure control compared to treatment guidance using office blood pressure measurement.

NCT ID: NCT00139581 Completed - Atopic Dermatitis Clinical Trials

Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects

Start date: September 2004
Phase: Phase 4
Study type: Interventional

This study is not being conducted in the United States. To investigate the relative efficacy of pimecrolimus cream 1% applied twice daily (b.i.d.) versus once daily (o.d.) in preventing the progression to disease "relapse".

NCT ID: NCT00139568 Completed - Constipation Clinical Trials

An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation

Start date: February 2005
Phase: Phase 3
Study type: Interventional

Tegaserod is an aminoguanidine indole compound and a member of a new class of 5-hydroxytryptamine (5-HT) agonists. Activation of 5-HT4 receptors triggers the release of neurotransmitters from the enteric nerves which in turn stimulate contractility and peristalsis. This study will investigate the efficacy and safety of tegaserod against chronic constipation in a Chinese population of adult men and women