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NCT ID: NCT02853773 Completed - Normal Subjects Clinical Trials

Effects of Consuming Artificial Sweeteners and Sugar on Cerebral and Physiological Responses

SUGART
Start date: February 2016
Phase: N/A
Study type: Interventional

This study aims at investigating the acute influence of artificially sweetened beverages consumption (as compared with sugar-sweetened beverages and water consumption) on brain responses to the viewing of food images, on physiological responses (gut-derived hormones and lipid metabolites) and on the food intake behavior.

NCT ID: NCT02853747 Completed - Hypertension Clinical Trials

Exercise and Arterial Modulation in Youth

ExAMIN YOUTH
Start date: May 2016
Phase:
Study type: Observational

The project is designed as a large scale, cross-sectional study. The aim of the study is to investigate the association of micro- and macrovascular function with physical fitness and body composition in primary school children.

NCT ID: NCT02850744 Terminated - Clinical trials for Glioblastoma Multiforme

Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients

Start date: July 2015
Phase: Phase 2
Study type: Interventional

PQR309 is an oral, dual pan-PI3K (phosphatidylinositol 3-kinase phosphoinositide 3-kinase) and mTOR (mammilian target of rapamycin) inhibitor that penetrates the blood-brain barrier at pharmacodynamically active concentrations. This study plans to evaluate PQR309 in treatment of patients with first progression of glioblastoma.

NCT ID: NCT02849080 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.

PIONEER 7
Start date: September 20, 2016
Phase: Phase 3
Study type: Interventional

This trial is globally conducted. The aim of this trial is to investigate Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation versus Sitagliptin in Subjects with Type 2 Diabetes Mellitus.

NCT ID: NCT02848521 Active, not recruiting - Clinical trials for Autosomal Dominant Polycystic Kidney Disease

A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe

ACQUIRE
Start date: October 2016
Phase:
Study type: Observational

This is a prospective, non-interventional study (NIS) measuring health-related quality of life (HRQoL), treatment satisfaction, and other patient-reported outcomes (PROs) of ADPKD patients in Europe.

NCT ID: NCT02847728 Completed - Lung Cancer Clinical Trials

Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice

Start date: July 28, 2016
Phase:
Study type: Observational

This is an observational, multicenter study in participants treated with nivolumab for the approved indications of melanoma and Lung cancer in Australia, the EU, Switzerland, the United Kingdom (UK), and the United States (US). The targeted countries in the EU for study participation include Austria, Belgium, Czech Republic, France, Germany, Hungary, Italy, Poland, and Spain. Study objectives are to assess the safety experience, survival, adverse event management, and outcomes of adverse events associated with nivolumab in routine oncology care facilities.

NCT ID: NCT02847663 Completed - Cold Clinical Trials

The Effect of Whole Body Cryotherapy on Recovery and Performance: a Randomized Controlled Trial

Cryotherapy
Start date: April 2016
Phase: N/A
Study type: Interventional

This study investigates the effects of whole-body cryotherapy vs. cold-water immersion after a muscle damage protocol.

NCT ID: NCT02846896 Completed - Clinical trials for Primary Biliary Cirrhosis

The Health Burden of Primary Biliary Cirrhosis (PBC) in Switzerland

Start date: December 2015
Phase: N/A
Study type: Observational [Patient Registry]

PBC is a rare, autoimmune, cholestatic liver disease with genetic and environmental pathogenetic factors. Data about epidemiology of PBC in Switzerland are completely lacking. Epidemiology can be a powerful tool in yielding important clues as to burden and etiology of diseases. In addition, the investigators study will be the first one carried out in the country on PBC, and therefore will raise disease awareness and create a network.

NCT ID: NCT02845726 Completed - Morbidity Clinical Trials

Biofilms on Short-term Indwelling Ureteral Stents

Start date: July 2016
Phase: N/A
Study type: Observational

This study is performed to analyze various aspects of biofilms on ureteral stents.

NCT ID: NCT02845063 Terminated - Clinical trials for Cardiovascular Disease

Effect of ACE Genotype on Cardiovascular Rehabilitation

ACE-REHAB
Start date: May 1, 2016
Phase: Phase 2
Study type: Interventional

The study aims to systematically investigate the interaction between training modality, ACE genotype and disease in heart patients whom complete a cardiovascular rehabilitation program. This is carried out with the goal to improve the benefit of cardiovascular rehabilitation for the patient by maximising adjustments in muscle structure and function with the intervention. A population of healthy individuals will be recruited who will carry out the same training program, in order to compare the training effects respective to the general population.