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NCT ID: NCT02861027 Completed - OSTEOARTHRITIS Clinical Trials

Effect of Functional Electrical Stimulation in Gluteus Medius in Rehabilitation After Total Hip Arthroplasty

EFESGMRTHA
Start date: July 2015
Phase: N/A
Study type: Interventional

Due to the importance of the functions of the gluteus medium, mainly during gait, it becomes essential to strengthening early in the musculature. The association of muscle strengthening with the Functional Electric Stimulation (FES) comes to accelerate stabilization of hip, leading to functional rehabilitation early and improves the quality of life through rehabilitation in social life and activities of daily life. Thus, it becomes a relevant study to assess objectively the implications of FES in muscle strengthening of gluteus medium associated with the Physiotherapy Protocol Total Hip Arthroplasty (PPTHA), through the assessment of motor performance in patients undergoing surgery for Total Hip Arthroplasty (THA), aiming to better rehabilitation strategies for this population. The objective of the research is to assess the effects of functional rehabilitation through PPTHA associated with FES in the gluteus medium compared only with the PPTHA, in patients undergoing surgery for THA. The principal hypothesis is that there is difference between the functional rehabilitation of the patients undergoing PPTHA associated with the FES of gluteus medium, after THA and the patients submitted only to PPTHA.

NCT ID: NCT02860689 Completed - Spinal Cord Injury Clinical Trials

Predictive Factors for Male Sexual Dysfunction After Traumatic Spinal Cord Injury

Start date: March 2015
Phase: N/A
Study type: Observational [Patient Registry]

Objective: To analyze the association between sexual function of men with spinal cord injury with possible predictive factors for dysfunction.

NCT ID: NCT02860637 Completed - Spinal Cord Injury Clinical Trials

Level and Degree of Spinal Cord Injury and Its Impact on Male Sexual Function

Start date: March 2015
Phase: N/A
Study type: Observational

In addition to the motor and sensory functions, sexual function changes after spinal cord injury and is considered one of the most common problems, ranging from a decrease in sexual desire to disturbances of erection, orgasm and ejaculation. Objective: To assess the impact of the complexity of traumatic spinal cord injury in male sexual function.

NCT ID: NCT02857426 Completed - Lymphoma Clinical Trials

A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

CheckMate 647
Start date: October 21, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Nivolumab is effective in the treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

NCT ID: NCT02857127 Completed - Motor Activity Clinical Trials

Physical Activity Promotion in Primary Health Care Settings

Start date: July 2014
Phase: N/A
Study type: Interventional

A quasi experimental study evaluating the effectiveness of a walking program at primary health care settings in a low-income area

NCT ID: NCT02856984 Completed - Clinical trials for Zika Virus Disease (Disorder)

Zika in Infants and Pregnancy (ZIP)

Start date: June 2016
Phase:
Study type: Observational

The overall objective of this multisite, multicountry Zika in Infants and Pregnancy (ZIP) study is to assess the strength of the association between Zika virus infection (ZIKV) during pregnancy and adverse maternal/fetal outcomes and the risk of vertical transmission. The study will prospectively enroll a cohort of pregnant women up to 17 weeks and 6 days gestation and subjects at any gestational age with acute Zika infection, confirmed by serology or PCR (polymerase chain reaction) test. The study will follow these women through their pregnancy to identify for clinical evidence of acute ZIKV, while controlling for potential confounders. Outcomes in the women, the developing fetus, and infants will be assessed. All protocol-specified data will be recorded and entered in a central data management system for the purposes of analysis of composite data from the study.

NCT ID: NCT02856919 Completed - Clinical trials for Chronic Persistent Vascular Facial Erythema

A Multicenter, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Once Daily Mirvaso® Gel in Patients With Chronic Persistent Vascular Facial Erythema.

BR14004
Start date: June 13, 2016
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy of Mirvaso® in the treatment of chronic persistent vascular facial erythema, after 4 weeks of treatment, by the Clinician erythema assessment.

NCT ID: NCT02856113 Completed - Clinical trials for Diabetes Mellitus, Type 2

Phase 3 Alogliptin Pediatric Study

Start date: October 14, 2016
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to evaluate the efficacy of alogliptin 25 milligram (mg) once daily compared to placebo when administered as monotherapy, or when added onto a background of metformin alone, insulin alone, or a combination of metformin and insulin, as measured by the glycosylated hemoglobin (HbA1c) change from Baseline at Week 26 in pediatric participants with type 2 diabetes mellitus (T2DM).

NCT ID: NCT02855944 Completed - Ovarian Cancer Clinical Trials

ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Start date: March 1, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine how patients with ovarian, fallopian tube, and primary peritoneal cancer will best respond to treatment with rucaparib versus chemotherapy.

NCT ID: NCT02854436 Completed - Prostatic Neoplasms Clinical Trials

An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies

Galahad
Start date: August 31, 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy, safety, and pharmacokinetics of niraparib in men with metastatic castration-resistant prostate cancer (mCRPC) and deoxyribonucleic acid (DNA) repair anomalies.