Clinical Trials Logo

Filter by:
NCT ID: NCT00204022 Completed - Lupus Nephritis Clinical Trials

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis.

MAINTAIN
Start date: February 2001
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether mycophenolate mofetil is superior to azathioprine to prevent flares of lupus nephritis.

NCT ID: NCT00199212 Completed - Clinical trials for Carcinoma Breast Stage IV

PS-341 in Combination With Herceptin in Advanced Breast Cancer That Overexpresses HER-2

Start date: October 2003
Phase: Phase 1
Study type: Interventional

The main objective of this study is to determine the feasibility of the combination of the proteasome inhibitor bortezomib (PS-341, Velcade) with trastuzumab (Herceptin) and to determine the best dose of bortezomib to combine with two trastuzumab schedules, weekly and 3-weekly.

NCT ID: NCT00199173 Completed - Colorectal Neoplasm Clinical Trials

Comparing Hepatic Intra-arterial Injection of Yttrium-90 Microspheres Versus Fluorouracil (5FU) in Colorectal Cancer Metastatic to the Liver Only

Start date: n/a
Phase: Phase 3
Study type: Interventional

This is a Phase III trial comparing hepatic intra-arterial injection of Yttrium-90 microspheres (selective internal radiation [SIR] spheres) versus infusional intravenous (IV) 5FU in colorectal cancer metastatic to the liver only and refractory to standard IV chemotherapy.

NCT ID: NCT00199160 Completed - Clinical trials for Head and Neck Neoplasms

Efficacy and Activity of BAY 43-9006 in Patients With Recurrent and/or Metastatic Head and Neck Cancer

Start date: April 2005
Phase: Phase 2
Study type: Interventional

This is a Phase II trial evaluating the efficacy and the biological activity of BAY 43-9006 in patients with recurrent and/or metastatic head and neck cancer.

NCT ID: NCT00199134 Completed - Breast Cancer Clinical Trials

FRAGRANCE Part A Safety: Study to Find a Genetic Signature of de Novo Resistance to Letrozole

Start date: November 2004
Phase: Phase 2
Study type: Interventional

Find a genetic signature of de novo resistance to letrozole in adjuvant breast cancer;

NCT ID: NCT00197184 Completed - Hepatitis B Clinical Trials

Long Term Follow-up Study at Years 2, 3, 4 and 5 Where 2 Dosing Schedules of the Combined Hepatitis A and B Vaccine Were Compared

Start date: November 1, 2003
Phase: Phase 3
Study type: Interventional

To evaluate the persistence of anti-hepatitis A virus (HAV) and anti-hepatitis B surface antigen (HBs) antibodies up to 2, 3, 4 and 5 years after administration of the first dose of the study vaccine. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

NCT ID: NCT00197158 Completed - Hepatitis B Clinical Trials

Comparison of Monodose and Multidose Presentations of GSK Biologicals' Hepatitis B Vaccine in Terms of Immune Response

Start date: March 2005
Phase: Phase 4
Study type: Interventional

GSK Biologicals' currently licensed multidose hepatitis B vaccine will be compared to the currently licensed monodose hepatitis B vaccine in a population with well documented hepatitis B immunological response to the vaccine (Belgium).

NCT ID: NCT00196963 Completed - Clinical trials for Infections, Meningococcal

Evaluate 4 Different Formulations of Meningococcal Serogroups A, C, W-135, Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 15-19 Yrs

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity, safety and reactogenicity of one dose of four different formulations of the MenACWY conjugate vaccine when given to healthy subjects aged 15-19 years. The selection of the best formulation will be based on data obtained up to one month after the vaccine dose.

NCT ID: NCT00196950 Completed - Clinical trials for Infections, Meningococcal

Study to Evaluate Meningococcal Serogroups A,C,W-135,Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 18-25 Years

Start date: September 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, reactogenicity, immunogenicity and persistence up to three years after administration of one dose of the MenACWY conjugate vaccine when given to young adults aged 18-25 years.

NCT ID: NCT00196794 Completed - Diarrhea Clinical Trials

A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea

Start date: April 2005
Phase: Phase 3
Study type: Interventional

Approximately 520 patients will be entered into this study taking place throughout Australia and Europe. This study aims to determine if an investigational drug is safe and effective for treating symptoms of C. difficile-associated diarrhea (CDAD) and lowering the risk of repeat episodes of CDAD. The investigational drug will be evaluated in comparison to current standard antibiotic treatment, so all patients will receive active medication. All study related care is provided including doctor visits, physical exams, laboratory tests, and study medication. The total length of participation is approximately 6 weeks.