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NCT ID: NCT01308021 Completed - Hay Fever Clinical Trials

Clinical Efficacy and Safety of gpASIT+TM to Treat Seasonal Allergic Rhinoconjunctivitis

Start date: December 2010
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of grass pollen-derived peptides administrated orally to treat seasonal allergic rhinoconjunctivitis.

NCT ID: NCT01307696 Completed - Umbilical Hernia Clinical Trials

Self-Expanding Multi-Layered Partially Resorbable Lightweight Polypropylene Mesh Device (Proceed Ventral Patch® Or Pvp®) For The Treatment of Small and Medium Umbilical Ventral Hernias

Start date: August 2010
Phase: N/A
Study type: Observational

Meshes-devices using dual-sided mesh technology have been developed for the specific indication of small ventral hernias. The design of these meshes allows introduction of a mesh of appropriate size to cover the hernia defect, through a small incision. This technique is very attractive for the surgeon and the patients because the mesh usually can be introduced through a nearly invisible scar in the umbilicus. The avoidance of fixation sutures omits the pain related to these sutures. Short-term results and patient satisfaction are very favorable, encouraging the surgeons to continue with the technique, although long-term results of these meshes in good quality studies are lacking.

NCT ID: NCT01307423 Completed - Psoriatic Arthritis Clinical Trials

Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis (PsA)

PALACE4
Start date: December 9, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis who have not been previously treated with DMARDs. Apremilast is proposed to improve signs and symptoms of psoriatic arthritis (tender and swollen joints, pain, physical function) in treated patients.

NCT ID: NCT01307397 Completed - Malignant Melanoma Clinical Trials

A Study of Vemurafenib in Participants With Metastatic Melanoma

Start date: March 1, 2011
Phase: Phase 3
Study type: Interventional

This multi-center study evaluates the safety and efficacy of vemurafenib in participants with BRAF V600 mutation-positive, surgically incurable, and unresectable Stage IIIC or IV (American Joint Committee on Cancer [AJCC]) metastatic melanoma.

NCT ID: NCT01306214 Completed - Obesity Clinical Trials

Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus

Start date: February 2011
Phase: Phase 3
Study type: Interventional

This trial will evaluate use of BI 10773 as add-on to insulin regimen alone or with metformin in patients with typr 2 diabetes. Both lowering glucose and HbA1c and reducing the use of insulin in this population would provide significant new information for the BI 10773 use and would offer a potential new therapeutic option in this population.

NCT ID: NCT01306149 Completed - Clinical trials for Complication of Peritoneal Dialysis

Natural History of Mineral Metabolism Parameters and Protein-bound Toxins in Incident Peritoneal Dialysis Patients

Start date: July 2002
Phase: N/A
Study type: Observational

The aims of this study are 1. To evaluate the natural history of plasma concentrations and renal and peritoneal clearances of small water-soluble uremic retention molecules (URM), 'middle molecules', and protein bound URM in incident peritoneal dialysis (PD) patients. 2. To evaluate the natural history and determinants of the generation rate of URM originating from bacterial protein fermentation in PD patients. 3. To evaluate the natural history of biochemical parameters of mineral metabolism in incident PD patients.

NCT ID: NCT01305577 Completed - Clinical trials for Moderate or Severe Submental Fullness

Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat

Start date: December 2010
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).

NCT ID: NCT01304836 Completed - Clinical trials for Kidney Transplantation

A Study Looking at Diabetes in Kidney Transplant Recipients Receiving Immunosuppressive Regimen With or Without Steroids

ADVANCE
Start date: January 22, 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to focus on potential differences in the occurrence of new-onset Diabetes Mellitus (a glucose metabolism disorder) when two different regimens of immunosuppressive treatment are compared.

NCT ID: NCT01304394 Completed - Clinical trials for Infant, Premature, Diseases

Safety During Use of Paediatric Triple Chamber Bag Formulas

Start date: February 2008
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to provide daily information on the performance safety of the Ped3CB in practical therapeutic use in pediatric patients.

NCT ID: NCT01303796 Completed - Clinical trials for Acute Myeloid Leukemia

A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia

SEAMLESS
Start date: October 1, 2011
Phase: Phase 3
Study type: Interventional

This Phase 3 study assesses two drug regimens as the initial treatment of patients who are at least 70 years of age and have newly diagnosed acute myeloid leukemia (AML) for whom the doctor does not recommend the use of standard intensive treatment or the patient has decided not to receive standard intensive treatment after being fully informed about its benefits and risks by his/her doctor. The two drug regimens are sapacitabine administered in alternating cycles with decitabine or decitabine alone. The purpose of the study is to learn which drug regimen is more likely to keep AML in check as long as possible.