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NCT ID: NCT02205255 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

BACE Trial Substudy 2 - FarmEc Substudy

FarmEc
Start date: August 1, 2014
Phase: Phase 3
Study type: Interventional

A second sub-analysis of the BACE trial will include a detailed cost-effectiveness study.

NCT ID: NCT02205242 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

BACE Trial Substudy 1 - PROactive Substudy

PROactive
Start date: September 2014
Phase: Phase 3
Study type: Interventional

A first sub-analysis of the BACE trial will address physical activity levels in a subgroup of the intervention study with portable validated activity monitors.

NCT ID: NCT02205138 Completed - Clinical trials for Degenerative Disc Disease

Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion

Start date: October 2014
Phase: Phase 2
Study type: Interventional

Among existing surgical techniques, spinal fusion is considered as the gold standard to treat a broad spectrum of degenerative spine disorders, including spondylolisthesis and scoliosis, with regard to pain reduction and functional improvement. However, pseudarthrosis and failure to relieve low back pain are unfortunately still frequent, irrespective of the type of procedures and grafts used by the surgeon. The present Phase 2a study aims at demonstrating the safety and efficacy of ALLOB®, a proprietary population of allogeneic osteoblastic cells, in lumbar spinal fusion.

NCT ID: NCT02203331 Completed - Endometriosis Clinical Trials

Bay98-7196, Dose Finding / POC Study

Start date: October 16, 2014
Phase: Phase 2
Study type: Interventional

Purpose of the study is to test efficacy and safety of BAY98-7196 intravaginal ring as a new treatment option for patients with endometriosis-associated pelvic pain

NCT ID: NCT02203214 Completed - Clinical trials for Anterior Cruciate Ligament Rupture

Induced ACL Healing With the Ligamys Technique: a Prospective, Multicenter Observational Case Series

Ligamys
Start date: August 2013
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety and effectiveness of the Ligamys technique for the treatment of acute ruptures of the anterior cruciate ligament in a multicenter routine clinical setting. To conduct a long-term follow-up of the case series as a post-market product surveillance endeavor.

NCT ID: NCT02202850 Completed - Clinical trials for Ankylosing Spondylitis

Defining Remission With Etanercept in AS in Real Life Clinical Practice

REACH AS
Start date: August 12, 2014
Phase:
Study type: Observational

Determine which remission criterion at Month 6 predicts remission at Month 12 the best.

NCT ID: NCT02202837 Completed - Clinical trials for Rheumatoid Arthritis

Study With Etanercept Focusing on Remission and Predictability of Remission in Real Life Clinical Practice

REACH RA
Start date: August 12, 2014
Phase:
Study type: Observational

Defining Which Remission Criterion at Month 6 Predicts Remission at Month 12 in a Real Life Clinical Practice, in a Cohort of Rheumatoid Arthritis Patients Treated with Etanercept

NCT ID: NCT02201940 Completed - Clinical trials for Hepatitis C Virus Infection

Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection

ASTRAL-1
Start date: July 2014
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of sofosbuvir/velpatasvir (SOF/VEL) fixed dose combination (FDC) for 12 weeks in adults with chronic genotype 1, 2, 4, 5, or 6 hepatitis C virus (HCV) infection.

NCT ID: NCT02201511 Completed - Healthy Clinical Trials

A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The study is designed to understand the blood concetration of PF-06412562 and its metabolite, PF-06663872, following a single oral dose of a modified release formulation. The study will include two doses of the PF-06412562 modified release formulation to understand the proportionality. Effect of food on absorption of PF-06412562 from the modified release formulation will also be investigated in this study.

NCT ID: NCT02201251 Completed - Epilepsy Clinical Trials

A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy

Start date: October 6, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety of topiramate monotherapy compared with levetiracetam another standard antiepileptic drug (AED), as monotherapy for new-onset or recent-onset epilepsy (seizure disorder) on pediatric growth and maturation, bone mineralization, and kidney stone formation in children aged 2 to 15 years.