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NCT ID: NCT03918460 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

ANEUFIX for Endoleak Type II Repair

Start date: May 13, 2020
Phase: N/A
Study type: Interventional

The study is non-randomized, multicenter international safety, performance and clinical benefit outcome assessment of ANEUFIX to treat patients with isolated type II endoleak in the presence of a growing AAA-sac following an EVAR procedure more than 6 months ago.

NCT ID: NCT03913299 Recruiting - Surgery Clinical Trials

Frailty Assessment by Edmonton Frail Scale to Predict Outcome in Patients Undergoing Cardiovascular Surgery

FRAIL-HEART
Start date: April 23, 2019
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to assess frailty of patients admited for cardio-vascular surgery in Cliniques Universitaires Saint Luc in Brussels. And analyse the correlation between frailty, functionnal decline and postoperative mortality.

NCT ID: NCT03911700 Recruiting - Clinical trials for Open Midline Laparotomy

Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

PREVENT
Start date: December 12, 2019
Phase: N/A
Study type: Interventional

This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for incisional hernia after open midline laparotomy surgery.

NCT ID: NCT03910374 Recruiting - Clinical trials for Cranial Sutures; Closure

Role of Leukocyte- and Platelet-Rich Fibrin Membranes in Endoscopic Endonasal Skull Base Reconstruction

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Prospective investigation of the effectivity of L-PRF membranes for skull base reconstruction after endoscopic endonasal skull base surgery (transsphenoidal) versus classical closure techniques.

NCT ID: NCT03905915 Recruiting - Preoperative Clinical Trials

Virtual Reality (VR) to Reduce Preoperative Anxiety.

RVAQUA
Start date: February 26, 2019
Phase: N/A
Study type: Interventional

Most patients awaiting surgery show significant anxiety score which can be influenced by the fear of anesthesia or surgery but also by the context of care. These anxious patients will have more postoperative complications and can also develop chronic pain. The Virtual reality AQUA module induces hypnosis and is specially designed to reduce anxiety. The purpose of the study is to examine the effect of a virtual reality session on preoperative anxiety.

NCT ID: NCT03905707 Recruiting - Clinical trials for Short Bowel Syndrome

Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS

EASE SBS 2
Start date: May 7, 2019
Phase: Phase 3
Study type: Interventional

The primary objective of the trial is to evaluate the long-term safety of glepaglutide treatment in patients with short bowel syndrome (SBS). Glepaglutide is the International Nonproprietary Name and USAN for ZP1848.

NCT ID: NCT03904888 Recruiting - Inguinal Hernia Clinical Trials

Conventional Versus Robot Assisted Laparoscopic Inguinal Hernia Repair

Start date: September 23, 2019
Phase: N/A
Study type: Interventional

Evaluate the early postoperative course of patients undergoing laparoscopic inguinal hernia repair with either a conventional or a robot assisted approach and with or without the injection of the trocar wounds with a local anesthetic.

NCT ID: NCT03903835 Recruiting - Clinical trials for Metastatic Castration-resistant Prostate Cancer (mCRPC)

ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer

ProBio
Start date: February 1, 2019
Phase: Phase 3
Study type: Interventional

ProBio is an international, outcome-adaptive, multi-arm, open-label, multiple assignment randomized biomarker driven platform trial in patients with metastatic prostate cancer. Patients will be randomized to control or experimental treatment arms. Patients in the control arm will receive standard of care following national guidelines. Patients in the experimental arm will be randomized to treatments based on a biomarker signature inferred from diagnostic tissue or liquid biopsy profiling. The predefined biomarker signatures are tumor properties or mutations in genes/pathways with previously demonstrated clinical validity (e.g. prognostic value or association with treatment response). The biomarker signatures are identified using a hybridisation capture gene panel specifically designed for prostate cancer.

NCT ID: NCT03901235 Recruiting - Efficacy and Safety Clinical Trials

MSC Intratissular Injection in Crohn Disease Patients

MSC
Start date: January 15, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The main objective is to assess the efficacy of local injection of MSC on the healing of refractory intestinal and perianal lesions in crohn disease. The second co-primary endpoint is safety.

NCT ID: NCT03900780 Recruiting - Clinical trials for Recurrent Implantation Failure

Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent Implantation Failure (RIF)