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NCT ID: NCT00198705 Completed - Infectious Disease Clinical Trials

Community Based Interventions to Reduce Neonatal Mortality in Bangladesh

Start date: June 2003
Phase: N/A
Study type: Interventional

This project delivers, promotes and facilitates services related to pregnancy, delivery and newborn care.

NCT ID: NCT00198679 Completed - Clinical trials for Skin Diseases, Infectious

Effect of Chlorhexidine Skin Cleansing on Skin Flora

Start date: March 2004
Phase: Phase 4
Study type: Interventional

Given the potential of skin cleansing with chlorhexidine as a safe, feasible, and cost-effective intervention for reducing neonatal death in developing country settings, this study follows a trial already underway in Nepal to test the impact of a single cleansing of the skin with baby wipes cotaining chlorahexidine.

NCT ID: NCT00198627 Completed - Infectious Disease Clinical Trials

Etiology, Prevention and Treatment of Neonatal Infections in the Community

Start date: December 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to determine what are the major types of bacteria that cause newborn infections in the community in rural Bangladesh and whether providing an obstetric and neonatal care package will reduce neonatal deaths by 40%.

NCT ID: NCT00198601 Completed - Infection Clinical Trials

Determination of Gentamicin Dosing in Neonatal Patients

Start date: August 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine what dosage of gentamicin for use in one-time administration device (Uniject) is appropriate.

NCT ID: NCT00162747 Completed - Skin Diseases Clinical Trials

Topical Therapy for Prevention of Infections in Preterm Infants

Start date: December 2001
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine how to best take care of the skin of preterm infants in order to prevent infections through the skin.

NCT ID: NCT00142389 Completed - Clinical trials for Pneumococcal Infections

Mother's Gift Project

Start date: August 2004
Phase: Phase 1/Phase 2
Study type: Interventional

This prospective randomized evaluation of pneumococcal vaccine immunization of pregnant mothers, followed by pneumococcal conjugate immunization of their children is designed to assess the effects of these strategies on the immunogenicity and safety of both vaccines. We hypothesize that maternal followed by infant immunization will be safe and will provide higher levels of antibody from birth through 12 months of age.

NCT ID: NCT00142285 Completed - Pneumonia Clinical Trials

Zinc Pneumonia Outpatient Trial in Children < 2 Years

Start date: November 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether zinc can be used in combination with standard antibiotics to reduce the duration of illness and the likelihood of treatment failure among children less than two years old who have non-severe, outpatient pneumonia.

NCT ID: NCT00142272 Completed - Cholera Clinical Trials

Single Dose Ciprofloxacin in the Treatment of Childhood Cholera:Randomized Controlled Clinical Trial

Start date: May 2001
Phase: Phase 3
Study type: Interventional

The study will be conducted to compare the efficacy and safety of a single dose of ciprofloxacin oral suspension 20 mg/kg with a 3-day course of erythromycin oral suspension administered in a dose of 12.5 mg/kg every 6 hours (12 doses) in the treatment of children, aged 2-15 years with clinically severe cholera due to V. cholerae O1 or O139. We hypothesize that single dose ciprofloxacin would result in similar outcome in the clinicalcurewith that of erythromycin given in multiple doses.

NCT ID: NCT00139334 Completed - Clinical trials for Infections, Rotavirus

A Study to Test 2 Doses of the HRV Vaccine Given With or Without OPV in Healthy Infants in Bangladesh

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The main objective of this study is to provide immunogenicity data for GSK Biologicals' HRV vaccine when co-administered with OPV or when given alone (HRV vaccine dose given 15 days after the OPV dose).

NCT ID: NCT00128557 Completed - Clinical trials for Vitamin A Deficiency

Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%. The trial will also evaluate whether the survival impact of newborn vitamin A dosing is modified by concurrent weekly, routine maternal vitamin A or beta-carotene supplementation during pregnancy through three months postpartum, gestational age and birth size.