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NCT ID: NCT00959283 Completed - Clinical trials for Myeloid Proliferations Associated With Down Syndrome

Study of Blood Samples From Newborns With Down Syndrome

Start date: February 23, 2009
Phase:
Study type: Observational

This research study is looking at blood samples from newborns with Down syndrome. Studying the genes expressed in samples of blood from patients with Down syndrome may help doctors identify biomarkers related to cancer.

NCT ID: NCT00958841 Completed - Pancreatic Neoplasm Clinical Trials

Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin

Start date: September 2009
Phase: Phase 2
Study type: Interventional

This study will assess the effectiveness and safety of pasireotide long-acting release in patients who have rare tumors of neuroendocrine origin.

NCT ID: NCT00957996 Completed - Fatigue Clinical Trials

Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza

Start date: October 2009
Phase: Phase 3
Study type: Interventional

This is a Phase 3, open-label, randomized study of the antiviral activity, safety, and tolerability of intravenous Peramivir in hospitalized subjects with confirmed or suspected influenza infection.

NCT ID: NCT00957749 Withdrawn - Clinical trials for Molybdenum Cofactor Deficiency Type A

Study of cPMP (Precusor Z) to Treat Molybdenum Cofactor Deficiency (MoCD) Type A

Start date: August 2009
Phase: Phase 1/Phase 2
Study type: Interventional

Molybdenum Cofactor Deficiency Type A (MoCD) is a very rare autosomal recessive disorder that is essentially fatal early in life. Naturally occurring cPMP is present in the body of all healthy normal individuals. It is processed to molybdopterin, which is further processed to molybdenum cofactor. Molybdenum cofactor is essential for the function of important enzymes. There is currently no treatment for MoCD, and affected infants develop severe neurological damage which often results in infant death. This study is the first clinical trial to investigate the potential of replacement of cPMP to infants with MoCD Type A. The safety, tolerability, and pharmacodynamics of daily intravenous administration of cPMP over 3 months will be determined.

NCT ID: NCT00957086 Active, not recruiting - Clinical trials for Carcinoma, Squamous Cell of Head and Neck

Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer

Start date: August 13, 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to improve the loco-regional control rate and overall survival of locally advanced head and neck squamous carcinoma (HNSCC). The investigators hypothesize that the addition of nimotuzumab (a recombinant humanized murine immune antibody that blocks both epidermal growth factor (EGF) and transforming growth factor (TGF)) to the current gold standard of concurrent chemoradiotherapy (CCRT) (7)(8), an adjuvant setting in patients after resection of their locally advanced HNSCC will confer therapeutic advantage.

NCT ID: NCT00954746 Completed - Dupuytren's Disease Clinical Trials

Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859

Start date: July 2009
Phase: N/A
Study type: Observational

The purpose of study AUX-CC-860 is to assess the durability of response of the AA4500 treatment regimen. This study will also evaluate long-term safety and progression of disease in joints.

NCT ID: NCT00954057 Completed - Clinical trials for Thyroid-Related Eye Disease

Pilot Study to Determine Safety and Efficacy of Orbital Injections of LIPO-102 in Patients With Symptomatic Exophthalmos Associated With Thyroid-related Eye Disease (TED)

Start date: September 2009
Phase: Phase 2
Study type: Interventional

This is a pilot study to determine the safety and efficacy of orbital injections of LIPO-102.

NCT ID: NCT00953732 Completed - Actinic Keratosis Clinical Trials

A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies

Start date: August 2009
Phase: Phase 3
Study type: Observational

This study is designed to follow up patients who have achieved complete clearance of AK lesions at the Day 57 visit having completed the PEP005-016 or PEP005-025 studies over a 12 month period to assess both recurrence of Actinic Keratosis (AK) lesions and long term safety in the selected treatment area.

NCT ID: NCT00953173 Completed - Obesity Clinical Trials

HERO Study: Helping Evaluate Reduction in Obesity

Start date: December 2009
Phase: N/A
Study type: Observational

A prospective, international, multi-center study of clinical outcomes and estimated healthcare resource expenditures associated with the treatment of obesity using the LAP-BAND AP® Adjustable Gastric Banding System.

NCT ID: NCT00952783 Completed - Actinic Keratosis Clinical Trials

A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study

Start date: July 2009
Phase: Phase 3
Study type: Observational

This study is designed to follow up patients, who have achieved complete clearance of AK lesions (lesion count of 0) at Day 57 in the PEP005-020 study, over a 12 month period to assess both recurrence of Actinic Keratosis (AK) lesions and long term safety in the selected treatment area.