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NCT ID: NCT01444105 Completed - Open-angle Glaucoma Clinical Trials

Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty

Start date: September 2011
Phase: N/A
Study type: Interventional

Evaluation of intraocular pressure (IOP) lowering effect of two iStent stents versus a SLT procedure in subjects with open-angle glaucoma on one ocular hypotensive medication.

NCT ID: NCT01444040 Completed - Open-angle Glaucoma Clinical Trials

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Start date: September 2011
Phase: Phase 4
Study type: Interventional

Evaluation of the intraocular pressure (IOP) lowering effect of two iStent inject devices versus medical therapy in eyes of subjects with primary open-angle glaucoma, pseudoexfoliative glaucoma, or ocular hypertension naïve to medical and surgical therapy.

NCT ID: NCT01443988 Completed - Open-angle Glaucoma Clinical Trials

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost

Start date: September 2011
Phase: Phase 4
Study type: Interventional

Evaluation of the intraocular pressure (IOP) lowering effect of two iStent devices versus medical therapy in eyes of subjects with primary open-angle glaucoma, pseudoexfoliative glaucoma, or ocular hypertension naïve to medical and surgical therapy.

NCT ID: NCT01265524 Completed - Heart Failure Clinical Trials

Evaluation of CLP in Heart Failure Patients With Chronic Kidney Disease

Start date: April 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effects of CLP on serum potassium and signs and symptoms of fluid overload in heart failure patients with chronic kidney disease.

NCT ID: NCT01252914 Completed - Clinical trials for Subject With Primary Open-angle Glaucoma (POAG)

A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With One Suprachoroidal Stent

Start date: December 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of one iStent supra stent in the reduction of intraocular pressure associated with primary open-angle glaucoma.

NCT ID: NCT01252888 Completed - Clinical trials for Subjects With Primary Open-angle Glaucoma (POAG)

Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two iStents

Start date: December 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess efficacy and safety of two iStents for the reduction of intraocular pressure associated with primary open-angle glaucoma.

NCT ID: NCT01252862 Completed - Clinical trials for Subjects With Primary Open-angle Glaucoma (POAG)

Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents

Start date: December 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the intraocular pressure (IOP) lowering effect of two iStent devices in eyes of subjects with primary open-angle glaucoma

NCT ID: NCT01252849 Completed - Clinical trials for Primary Open Angle Glaucoma (POAG)

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Start date: December 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the iStent medical device that is implanted into the eye and designed to reduce eye pressure in patients with your condition.

NCT ID: NCT01075906 Completed - Clinical trials for Familial Mediterranean Fever

Pharmacokinetics Study of Colchicine in Familial Mediterranean Fever (FMF) Patients

Start date: August 2010
Phase: Phase 1
Study type: Interventional

Colchicine is widely recognized as safe and effective treatment of Familial Mediterranean Fever (FMF) in children and adults. Colchicine is currently used to treat FMF in younger patients by inexact dosing through breaking or crushing adult-dose tablets. An age-appropriate sprinkle formulation will allow for more accurate dosing in pediatric patients. The primary objective of this study is to evaluate and compare the steady-state pharmacokinetics of multiple oral doses of colchicine sprinkle capsules administered to pediatric and adult FMF patients. Secondary objectives include evaluation of the safety and tolerability of this regimen in pediatric and adult FMF patients and measurement of the levels of acute phase reactants (i.e, serum amyloid A [SAA], erythrocyte sedimentation rate [ESR], C-reactive protein [CRP]) at baseline and after dosing.

NCT ID: NCT00913029 Completed - Glaucoma Clinical Trials

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)

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Start date: May 2009
Phase: Phase 4
Study type: Interventional

Prospective, unmasked, randomized evaluation of the iStent in patients with primary open-angle glaucoma. Patients will be randomized to one of two groups: 1) iStent, or 2) medication.