Stress CMR in Pediatric Patients With Suspected Coronary Artery Disease

Status Completed

Clinical Trial Summary

stress cMRI with Dobutamine stress agent (stress cMRI), represent the combination of two orders of exams routinely performed (cMRI and stress diagnostic series of exams) without additional risk for the patient, but with the advantage of non-invasiveness and lack of radiation, and less laborious for the participants

Clinical Trial Description

Surgical revascularization or angioplasty are therapeutic options for coronary lesions even in infants and children. Pharmacological stress induced cMRI could provide crucial information such as coronary arteries origin and proximal pathway, wall motion abnormalities, myocardial perfusion and viability, enabling accurate monitoring of symptomatic and non-pediatric patients. Investigators would build a prospective series of stress cMRI exams in pediatric symptomatic and non-patients, with suspected or previously diagnosed coronary artery disease. Investigators would put the results in comparison with ECG, Exercise test, stress Cardiac Ultrasound and Angiography. At the end of the study, if supported by results, the aim is to replace the current diagnostic procedure (ECG, Exercise test, stress Cardiac Ultrasound and Angiography) which need long hospitalization, expose the patient to radiation dose, is uncomfortable for the patient, and is characterized by a non-negligible risk due to invasive procedure, with a single exam (stress cMRI) which is dose-free, minimal risk related, without hospitalization, and less expensive for National Care System. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04022395
Study type	Interventional
Source	Istituto Giannina Gaslini
Contact
Status	Completed
Phase	N/A
Start date	October 18, 2018
Completion date	March 30, 2021

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06032572` - Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE)	N/A
Completed	`NCT05672862` - International Post-PCI FFR Extended Registry
Completed	`NCT04492423` - VerifyNow® PRUTest® Cardiovascular Population Expected Values On-Drug Study
Completed	`NCT01205776` - EXCEL Clinical Trial	N/A
Recruiting	`NCT01218776` - International Survey of Acute Coronary Syndromes in Transitional Countries
Completed	`NCT00046410` - Comparison of the Risk of Stroke With On- Versus Off-Pump Coronary Artery Bypass Grafting	N/A
Recruiting	`NCT04390672` - Multivessel TALENT	N/A
Completed	`NCT02784873` - High Intensity Interval Training in UK Cardiac Rehabilitation Programmes	N/A
Not yet recruiting	`NCT02895009` - Hemostatic Compression Patterns After Transradial Coronary Intervention	N/A
Completed	`NCT02948517` - Time Restricted Feeding for Weight Loss and Cardio-protection	N/A
Recruiting	`NCT02859480` - Dose-dependent Effect of Rosuvastatin on Long-term Clinical Outcomes After PCI	Phase 4
Completed	`NCT02382731` - Interventions to Support Long-Term Adherence aNd Decrease Cardiovascular Events Post-Myocardial Infarction	N/A
Completed	`NCT02510547` - Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the "CrossBoss First" Trial	Phase 4
Withdrawn	`NCT02418143` - A Study to Obtain Additional Information on the Use of CorMatrix® CanGaroo ECM® Envelope
Recruiting	`NCT01681381` - Evaluate Safety And Effectiveness Of The Tivoli® DES and The Firebird2® DES For Treatment Coronary Revascularization	N/A
Completed	`NCT02248415` - Administration of Warm Blood Cardioplegia With or Without Roller Pump	N/A
Recruiting	`NCT01207167` - Mediators of Atherosclerosis in South Asians Living in America
Completed	`NCT02088138` - Functional Electrical Stimulation in Cardiac Patients	N/A
Completed	`NCT02173067` - Anesthesia With Epinephrine in Diabetes Patients is Safe and Effective	N/A
Completed	`NCT02133807` - Specific Lp(a) Apheresis for Regression of Coronary and Carotid Atherosclerosis	Phase 3