Blood Pressure Responses to Different Exercise Modes in Coronary Artery Disease

Coronary Artery Disease Clinical Trial

Official title:

The Blood Pressure Responses to Different Exercise Models in Patients With Coronary Artery Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03847012
• Other study ID #: 201807117RIND
• Status: Completed
• Phase: N/A
• Start date: March 11, 2019
• Est. completion date: September 30, 2020

Study information

• Verified date: April 2021
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with coronary artery diseases (CAD) and to compare the effects of blood pressure responses after exercise training.

The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. The subjects performed the treadmill or stationary bicycle exercise randomly.

Description:

Considering cardiopulmonary rehabilitation intensity is often setting by heart rate clinically, and only few study focused on exercise responses patients with CAD, the purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with CAD and to compare the effects of blood pressure responses after exercise training.

This is a crossover trial study. The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. After at least 3 times of familiar with the cardiopulmonary rehabilitation training machine, the subjects performed the treadmill or stationary bicycle and exercise to personalized target heart rate for 10 minutes, take a rest until the heart rate recover to the resting heart rate, and then repeated the exercise in another exercise mode. The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: September 30, 2020
• Est. primary completion date: September 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

• patients with coronary artery diseases who are referred to phase II cardiopulmonary rehabilitation exercise training.

Exclusion Criteria:

• patients with non-coronary artery diseases

• atrial fibrillation

• neurological or musculoskeletal problems

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia

Intervention

Other:
• exercise
The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei city

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	age	questionnaire	baseline
Other	gender	questionnaire	baseline
Other	risk level of exercise	AACVPR Stratification Algorithm for Risk of Event. Include high, moderate and low risk	baseline
Other	co-morbidity	questionnaire	baseline
Other	medication	questionnaire	baseline
Other	level of exercise intensity	percent of heart rate reserve	baseline
Primary	heart rate	heart rate	Change from baseline heart rate at 6 weeks
Primary	blood pressure	blood pressure	Change from baseline blood pressure at 6 weeks
Secondary	perceived exertion scale	how effort the participant feel. Range from 1to 10. Higher values represent harder.	baseline and 6 weeks
Secondary	heart rate variability	heart rate variability	baseline and 6 weeks