Women Health Cohort for Breast, Bone and Coronary Artery Disease

Coronary Artery Disease Clinical Trial

— BBC  

Official title:

Women Health Cohort for Breast, Bone and Coronary Artery Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03235622
• Other study ID #: B-1707-406-102
• Status: Completed
• Phase: N/A
• First received: July 24, 2017
• Last updated: July 29, 2017
• Start date: March 2011
• Est. completion date: July 2017

Study information

• Verified date: July 2017
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

A single center cohort which enrolled women who performed mammography, bone densitometry (DEXA), and coronary CT angiography in Seoul National University Bundang Hospital from March 2011 to February 2013.

Description:

To evaluate whether bone mineral density and breast arterial calcification can predict coronary artery disease in women older than 40 years

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2100
• Est. completion date: July 2017
• Est. primary completion date: February 2013
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 40 Years and older

Eligibility

Inclusion Criteria:

• Women (= 40 years) who performed mammography, bone DEXA, and coronary CT angiography at health promotion center of Seoul National University Bundang Hospital.

Exclusion Criteria:

• Women who have history of breast surgery or intervention

• Women who have history of myocardial infarction or revascularization

• Too poor image quality of coronary CT angiography for interpretation

• Renal dysfunction with serum creatinine = 1.4mg/dL

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia

Intervention

Diagnostic Test:
• Coronary CT angiography
Presence of coronary plaques Characteristic of coronary plaques

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Presence of coronary plaque	Any coronary plaque in coronary CT angiography	5 years
Secondary	Characteristics of coronary plaque	Plaque characteristics (fibrosis, calcification, lipid, thrombosis) in coronary CT angiography	5 years
Secondary	Major adverse cardiovascular events	Cardiac death, nonfatal myocardial infarction, ischemic stroke, coronary revascularization	5 years