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NCT02394236 Clinical Trial

Aerobic Exercise and Oxygen Uptake Efficiency Slope in Coronary Artery Disease

Coronary Artery Disease Clinical Trial

Official title:
Continuous vs. Interval Exercise Training on Oxygen Uptake Efficiency Slope in Patients With Coronary Artery Disease

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02394236
Other study ID # 66/2011
Secondary ID
Status Completed
Phase Phase 2
First received March 16, 2015
Last updated March 19, 2015
Start date September 2012
Est. completion date November 2014

Study information
Verified date March 2015
Source Hospital TotalCor
Contact n/a
Is FDA regulated No
Health authority Brazil: Ethics Committee
Study type Interventional

Clinical Trial Summary

Thus, the purpose of the present study was to evaluate the effects of continuos exercise training (CET) and interval exercise trainining (IET) on oxygen uptake efficiency slope (OUES) in patients with coronary artery disease.

Description:

The oxygen uptake efficiency slope (OUES) is a submaximal index that incorporates cardiovascular, peripheral and pulmonary factors that determine ventilatory response to exercise. There is scarce information about the effects of the mode and intensity of exercise training on OUES in patients with coronary artery disease.

Recruitment information / eligibility
Status Completed
Enrollment 35
Est. completion date November 2014
Est. primary completion date October 2013
Accepts healthy volunteers No
Gender Both
Age group 49 Years to 75 Years
Eligibility Inclusion Criteria:

- stable coronary artery disease diagnosed by coronary angiography

Exclusion Criteria:

- unstable angina pectoris,

- complex ventricular arrhythmias,

- pulmonary congestion and

- orthopaedic or neurological limitations to exercise

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Other:
• Aerobic exercise training
The continuous exercise training was performed on a treadmill with a 50-minutes duration and intensity at ventilatory anaerobic threshold. The interval exercise training consisted of 7 sets of 3 minutes at respiratory compensation point and 7 sets of 3 minutes of exercise at moderate intensity corresponding to the ventilatory anaerobic threshold totaling 42 minutes

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Hospital TotalCor

Outcome
Type Measure Description Time frame Safety issue
Primary The oxygen uptake efficiency slope The oxygen uptake efficiency slope (OUES) is a submaximal index that incorporates cardiovascular, peripheral and pulmonary factors that determine ventilatory response to exercise. up to 3 months Yes
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