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Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents — ADAPT-DES  

Coronary Artery Disease Clinical Trial

Official title:
Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents

Clinical Trial Summary

Prospective, multicenter, registry of at least 11,000 (and up to 15,000) consecutive patients with coronary artery disease undergoing stent-assisted percutaneous coronary intervention (PCI) using DES without major procedural complications.

Clinical Trial Description

To determine:

1. the frequency, timing and correlates (clinical and angiographic) of drug-eluting stent (DES) thrombosis in a patient population with few clinical and angiographic exclusion criteria,

2. the relationship of aspirin and/or clopidogrel hyporesponsiveness, and general platelet reactivity to early and late DES thrombosis in separate phases stratified by whether the patient is taking dual (aspirin plus clopidogrel) or single (aspirin alone) antiplatelet therapy, and

3. combining the findings from the above 2 objectives, to identify a cohort representing a significant proportion of all patients at increased risk to have early and/or late DES stent thrombosis. ;

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00638794
Study type Observational
Source Cardiovascular Research Foundation, New York
Contact
Status Completed
Phase N/A
Start date January 2008
Completion date January 2013
View Details
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