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Effect of Creatine and L-Arginine on Endothelial Function

Coronary Artery Disease Clinical Trial

Official title:
Effect of Creatine and L-Arginine on Endothelial Function in Patients With Coronary Artery Disease

Clinical Trial Summary

The study is a double blind 2x2 factorial study. Patients with coronary disease will be randomly be assigned to L-arginine (9 g/day), creatine 21 g/d, both, or neither dietary supplement. The function of the endothelium will be tested using ultrasound before and after each treatment. These studies will help us understand why the endothelium is abnormal in patients with coronary artery disease and how L-arginine is acting on endothelial function.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00551434
Study type Interventional
Source Boston University
Contact
Status Completed
Phase N/A
Start date August 2002
Completion date December 2005
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