A Mechanistic Study of Inhaled Nitric Oxide in COPD

Status Recruiting

Clinical Trial Summary

There is a lack of effective treatments for chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension. Previous studies have found that inhaled nitric oxide (iNO) can reduce pulmonary artery pressure and improve exercise capacity in COPD with pulmonary hypertension patients. However, the specific mechanism is unclear. The study aims to evaluate pulmonary ventilation/perfusion, pulmonary artery pressure, oxygenation, symptoms and quality of life in COPD with pulmonary hypertension patients after short-term treatment with iNO. Observing a series of pathophysiological changes caused by the treatment of pulmonary hypertension with iNO in COPD, the investigators hope to provide new theoretical basis and research ideas.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05785195
Study type	Interventional
Source	China-Japan Friendship Hospital
Contact	Ruoxi He
Phone	+8618874167666
Email	heruoxi1985@yeah.net
Status	Recruiting
Phase	N/A
Start date	March 14, 2023
Completion date	March 31, 2024

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