Chronic Obstructive Pulmonary Disease Clinical Trial
Official title:
Diaphragm and Sternocleidomastoid Muscle Activation Patterns During Different Loaded Inspiratory Muscle Performance in Patients With Chronic Obstructive Pulmonary Disease
Verified date | March 2018 |
Source | National Taiwan University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lung, characterized by chronic cough, dyspnea, and sputum production. Inspiratory muscle weakness has been shown in patients with COPD, and inspiratory muscle training (IMT) is commonly applied to these patients. However, the optimal prescribed intensity of IMT for patients with COPD remains unclear. In healthy adults the accessory muscles would be recruited to assist ventilation with increasing ventilatory demand, but the activation pattern of accessory muscles has not been studied in patients with COPD during loaded condition such as IMT. Therefore, the purpose of this study is to exam diaphragm and sternocleidomastoid muscle activation using surface electromyography during loaded inspiratory muscle tests with intensity of 30% and 50% of maximal inspiratory pressure.
Status | Completed |
Enrollment | 30 |
Est. completion date | December 20, 2018 |
Est. primary completion date | December 20, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - age > 20 years old - has been diagnosis of chronic obstructive pulmonary disease with stable clinical condition with no infection or acute exacerbation in the previous four weeks - can cooperate with the measurements of this study Exclusion Criteria: - any clinical diagnosis that will influence the measurement, including any history of neuromyopathy - angina, acute myocardial infarction in the previous one month - pregnancy - participated in inspiratory muscle training program in the previous three months - any psychiatric or cognitive disorders, for example: Mini-Mental State Examination (MMSE) < 24, that will disturb the communication and cooperation of the study |
Country | Name | City | State |
---|---|---|---|
Taiwan | School and Graduate Institute of Physical Therapy of National Taiwan University | Taipei | Zhongzheng Dist |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Diaphragm and Sternocleidomastoid muscle activation | Root mean square values during different conditions | through the completion of the loaded inspiratory muscle test condition; it would take about 3 minutes | |
Primary | The mean median frequency of diaphragm and sternocleidomastoid muscle | The power spectrum is divided into two equal areas of the frequency value by median frequency to exam muscle fatigability | In one minute after the completion of the loaded inspiratory muscle test condition |
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