Chronic Obstructive Pulmonary Disease Clinical Trial
| Verified date | February 2019 |
| Source | KU Leuven |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Proprioceptive weighting changes may explain differences in postural control performance. In
addition, the respiratory movement has a disturbing effect on postural balance. Postural
balance seems to be impaired in individuals with respiratory disorders. Increased risk of
falling is reported in individuals with chronic obstructive pulmonary disease. Besides the
essential role of respiration, the diaphragm may also play an important role in the control
of the trunk and postural balance.
The aim of the study is to clarify whether proprioceptive postural control is impaired in
individuals with diaphragm paresis.
| Status | Withdrawn |
| Enrollment | 0 |
| Est. completion date | January 2015 |
| Est. primary completion date | December 2014 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years to 70 Years |
| Eligibility |
Inclusion Criteria individuals with diaphragm paresis: - Age: 18-70 years old - Unilateral or bilateral diaphragm paresis following paresis of phrenic nerve - Willingness to sign the informed consent Inclusion Criteria healthy controls: - Age: 18-70 years old - Spirometry: FEV1/FVC = 0.7 and FEV1 > 80% - Willingness to sign the informed consent Exclusion Criteria: - History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant - One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder - Respiratory disorder other than diaphragm paresis - Recent diagnosis of cancer - Significant cardiovascular comorbidity |
| Country | Name | City | State |
|---|---|---|---|
| Belgium | Katholieke Universiteit Leuven | Leuven | Vlaams-Brabant |
| Lead Sponsor | Collaborator |
|---|---|
| KU Leuven | Universitaire Ziekenhuizen Leuven |
Belgium,
Janssens L, Brumagne S, Polspoel K, Troosters T, McConnell A. The effect of inspiratory muscles fatigue on postural control in people with and without recurrent low back pain. Spine (Phila Pa 1976). 2010 May 1;35(10):1088-94. doi: 10.1097/BRS.0b013e3181bee5c3. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Proprioceptive postural control | Center of pressure displacement (force plate) in standing in response to local muscle vibration on ankle and back muscles to specifically detect the role of proprioception in postural control. | 1 year |
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